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Tag: "oral" at biology news

Live Recombinant Adenovirus Vaccine Technique Explored

...g School of Public Health. “The military developed oral vaccines for adenovirus years ago that safely prov...ers developed their vaccine prototype using canine oral papillomavirus (COPV), which behaves similarly to HPV. Research by other scientists showed that a va...

Molecular machine may lead to new drugs to combat human diseases

...umonia, and thrush, an infection of tissues in the oral cavity. This makes introns a potential target for therapeutics against these diseases by using a strategy called targeted trans-splicing in which introns are manipulated to cut out malfunctioning genes. Introns' unique capability of cutting and past...

BRCA1 causes ovarian cancer through indirect, biochemical route

...gh their life without interruption by pregnancy or oral contraceptive use are at highest risk for developing sporadic ovarian cancer," Dubeau explains. "So we had some clues that the cells that control the menstrual cycle-the ovarian granulosa cells-have an influence on ovarian cancer." But how? Was that...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

...ent it,?said Richard Lamont, Ph.D., a professor of oral biology at UF’s College of Dentistry and study inv...nderstand how P. gingivalis interacts with healthy oral tissues to cause such devastation. In this study, they used cutting-edge molecular research techniqu...

FDA Approves New Drug to Treat Type I and Type II Diabetes

...ype 2 diabetes already have several other types of oral therapies available. The safety and efficacy of Symlin were studied in approximately 5000 patients. Overall Symlin therapy was associated, in patients with both types of diabetes, with improvements in the control of blood glucose and with weight los...

Chemists identify key gene in development of type 1 diabetes

...mpound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achieve lasting protection, perhaps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effective gene therapy against the disease may take many years ...

Bone Density Recovers After Teens Stop Injected Contraceptive

...A had used other forms of contraception, including oral contraceptives. Oral contraceptives also contain h...me contain only progestin. It is not known whether oral contraceptive use affects bone mineral density and NICHD is currently supporting a study to address ...

Towards precise classification of cancers based on robust gene functional expression profiles

...mpound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achieve lasting protection, perhaps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effective gene therapy against the disease may take many years ...

Gene therapy promising for growing tooth-supporting bone

...sive environment for those pursuing careers in the oral sciences, with a focus in the area of restoration of oral-craniofacial tissues. Co-authors on the paper include Courtney A. Dunn, adjunct clinical lecturer in orthodontics; Qiming Jin, research associate in periodontics, prevention and geriatrics; M...

Medical molecules designed to respond to visible light that can penetrate tissue

...l, all of Virginia Tech. Brewer will also give an oral presentation on designing photochemical molecular devices and applications in photodynamic therapy and in solar energy conversion. Because of the detail offered by Mongelli's poster, Brewer says she will focus on the exciting potential of creating mo...

Discovery may lead to better Candidiasis drug

...ly occurring antifungal agent in saliva, kills the oral pathogen Candida albicans, the fungus responsible for most HIV-related oral infections. Researchers led by Mira Edgerton, D.D.S., Ph.D., discovered that histatin binds to a sp...

Canada approves marijuana-based pain spray

...ormulation allows for more flexible dosing than an oral tablet, well suited to the variable nature of neuropathic pain experienced by people with MS. “Because Sativex is designed for self-administration, this allows for flexible dosing and puts the patient in control of their pain,?said Dr. Gordon. “This...

Biomarkers isolated from saliva successfully predict oral and breast cancer

... genetic "biomarkers" isolated in saliva predicted oral squamous cell carcinoma in about nine out of 10 ca...ted saliva and blood from 32 patients with primary oral squamous cell carcinoma and 40 breast cancer patients, and matched each with saliva and blood from o...

A little stress gives beneficial oomph! to immune system

... study's lead author and an associate professor of oral biology and molecular virology, immunology and med...itha Viswanathan, a graduate research associate in oral biology at Ohio State, reported their findings online in the Proceedings of the National Academy of ...

Friendly bacteria in humans may protect against HIV

...ns of lactobacillus, commonly found colonizing the oral and vaginal cavities of humans. They do not cause ...at target mannose, Tao and his colleagues isolated oral and vaginal lactobacilli from healthy humans and tested the ability of different strains to bind to ...

Compounds in plastic packaging act as environmental estrogens altering breast genes

... After the morning poster session, he will give an oral presentation on "Estrogens as Carcinogens in the Human Breast." "Development of breast cancer entails multiple events, in which estrogen appears to play an important role," explained Russo. "Our laboratory has pioneered an in vitro system of cell tr...

South African Tribunal Asks For Damages Estimates in GSK AIDS Drug Case

...ate April or the first week of May 2005 to present oral arguments on these issues. "In our case, we will submit to the Tribunal evidence of the monetary damages suffered as a result of GSK's illegal actions in charging excessive AIDS drug prices in South Africa," said Michael Weinstein, AHF’s president. ...

OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies

... the 1960s and is still marketed in the U.S. as an oral formulation to treat intestinal parasites. The largest-ever Phase III clinical trial for visceral leishmaniasis was completed in November 2004 by OneWorld Health in collaboration with the Special Programme for Research and Training in Tropical Diseas...

The biggest family tree ever

... to written historical records that can be lost or oral histories that can fall into disuse, the information stored in people's genes persists. Cusanovich had his own DNA analyzed, which helped him trace his family to a time "when the crusaders were rolling through the Middle East." Many people conduct g...

Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes

...lycemic control (as evidenced by normal results of oral glucose tolerance testing in 4 of 5 recipients with sustained insulin independence) using significantly fewer islets," the authors write. "These findings may have implications for the ongoing transition of islet transplantation from clinical investig...

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