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Tag: "optimal" at biology news

Priming embryonic stem cells to fulfill their promise

...oteins as a way toidentify which combinations were optimal in producing differentiatedcells from stem cells,"... of these proteins, any one of which could formthe optimal "niche" for a desired type of differentiated cell.In their experiments, the UCSD researchers took ad...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...ES cells. More research isneeded to understand the optimal conditions for preparing human cellsfor therapeutic application.""We considered that one partial solution to the problem was to usehuman serum in the growth medium," Varki said. When the team grew thecells in heat-inactivated human serum specially se...

Same mutation aided evolution in many fish species, Stanford study finds

... tricks up its sleeve to push organisms towards an optimal form for their environment. Other Stanford researchers who participated in the study include graduate students Pamela Colosimo, PhD, first author on the study, and Kim Hosemann; technician Sarita Balabhadra; undergraduate Guadalupe Villarreal Jr.; t...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

...sence of growth hormone and IGF-1 are required for optimal performance on tests of learning and memory throughout life," they said. "Growth hormone/IGF-1 replacement in older animals reverses the age-related decline in cognitive function." The group also found that "cartilage degeneration that normally acco...

Implanted Devices Detect High-Risk Heart Failure Patients

...ke University Medical Center. Besides maintaining optimal electrical stimulation to the heart, these CRT-D (cardiac resynchronization therapy with defibrillation) devices are giving cardiologists a new view of subtle changes in a key measurement of heart health -- heart rate variability. Patients with littl...

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

...g experience. Thus it appears that there may be an optimal range for IL-1BETA, with either too much or too little inhibiting memory storage. Bilbo says, "The take-home message is that immune responses in a healthy brain are tightly regulated and controlled; any alteration in these responses is likely to caus...

Asthma gene clusters identified

...nsist of anti-inflammatory drugs, which may not be optimal for acute attacks," Dr. Hershey said. Previous studies using microarray technology have been conducted using RNA from adults with asthma, but this approach has not been successfully used in human studies involving children with asthma. In pediatrics...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...Some of the recommendations we have may not be the optimal doses.?/p> UF researchers have developed a pat... dosing decision is made. “We feel that’s not the optimal way go,?he said. “It doesn’t give you the full story ?it doesn’t tell you, for example, how quickly ...

Brain Scans Reveal How Gene May Boost Schizophrenia Risk

...es" prefrontal neurons (brain cells) to achieve an optimal signal-to-noise ratio, much like a fine-tuning dial on a radio. For the clearest signal, the "dial" must be turned in opposite directions, depending on which version of the COMT gene one inherits: up with val, down with met. In people with val and sc...

Turning viruses into allies against cancer

...s should help scientists evaluate the efficacy and optimal delivery system of their radio-virotherapy vector. "We expect this work will take another two years before this technology will be available for testing in patient studies," said Blechacz. ...

Too much water may be as dangerous as too little during long-distance athletic events

...l recommendations for fluid replacement may not be optimal for individual athletes of different body types and with varying degrees of training and heat acclimatization. ...

Bush, Cheney and Rumsfeld are now species of slime-mold beetles -- but strictly in homage

...l recommendations for fluid replacement may not be optimal for individual athletes of different body types and with varying degrees of training and heat acclimatization. ...

New design : complete

...l recommendations for fluid replacement may not be optimal for individual athletes of different body types and with varying degrees of training and heat acclimatization. ...

Alcohol consumption disrupts breastfeeding hormones

... to drink alcohol as an aid to milk production and optimal lactation. Recent surveys indicate that 25% of women report being encouraged by their health professionals to drink alcohol while breastfeeding. But as Mennella points out, "There was no valid scientific evidence to support this claim." To address t...

Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines

...d of research, there have been few ways to predict optimal drug design. The molecular targets of many drug candidates are unknown and are often difficult to tease out from among the thousands of gene products found in a typical organism. This “blindness?in the welter of potential cellular targets means that ...

Newest HIV drugs should be used with FUZEON(R)

...t chance of achieving undetectable viral load ?the optimal treatment goal for all people living with HIV. "Undetectable viral load should be the ultimate treatment goal for all triple-class experienced patients. FUZEON combined with the latest drugs now makes this much more achievable," explained Dr Mike Yo...

Deep thinking: Scientists sequence a cold-loving marine microbe

...ea to a variety of bacteria that live at different optimal temperatures," remarks Barbara Methé, a molecular biologist at TIGR and lead author of the PNAS paper. "This organism must adapt to extreme cold--in fact, it cannot live above room temperature. How does it cope in such freezing conditions?" Among co...

When it comes to cell entry, being average has its advantages

...r about 1,000 times thinner than a human hair ?are optimal for cellular entry. In a research article to be po...es to get in ?those in medication, say ?knowing an optimal particle size for entry is also helpful. "With nanotubes, we may be able to manufacture ones of a c...

Motor transport in bio-nano systems

...and filament arrangements, and have determined the optimal conditions for the transport of nanocargo in these...th the models the researchers can predict how this optimal motor concentration depends on the single motor properties. The theoretical results are in agreemen...

Most common lung cancers may begin in newly discovered cells

... Bender Kim and her colleagues do not yet know the optimal microenvironment for stem cells of the lung, including the roles of the neighboring cells that support the stem cells and specialized lung cells. Still, she says their studies are as rigorous as the generally accepted reports of stem cells found in t...

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