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Tag: "opioid" at biology news

Key Trigger Of Opioid Withdrawal Symptoms Found

...y that triggers some of the withdrawal symptoms of opioid drugs like morphine and heroin. They believe that...s may prove to be useful targets for management of opioid dependence," they wrote. The researchers also wrote that, since GABA is a neurotransmitter that inhi...

FDA Clears the Way for Generic Versions of Transdermal Patches to Treat Chronic Pain

... skin, this patch technology delivers fentanyl, an opioid pain medication that is slowly absorbed into the b...of chronic pain in patients who require continuous opioid analgesia for pain that cannot be managed by acetaminophen-opioid combinations, non-steroidal analge...

Scientists Propose Sweeping Changes to Naming of Bird Neurosystems to Acknowledge Their True Brainpower

... skin, this patch technology delivers fentanyl, an opioid pain medication that is slowly absorbed into the b...of chronic pain in patients who require continuous opioid analgesia for pain that cannot be managed by acetaminophen-opioid combinations, non-steroidal analge...

Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief

... two kinds of stress-induced analgesia mechanisms, opioid and nonopioid (or "opioid independent"). Hohmann and colleagues discovered that the opioid-independent form was produced by release of the brain's own marijuana-like compounds. "We showed that cannabinoid receptors were involved in this remarkable p...

Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'

...hine, methadone and anesthetics also act on the mu opioid receptor system to reduce pain. Because the endo...ging of the participants' endogenous pain-reducing opioid systems sheds new light on why the placebo effect occurs. The imaging method used in the study invo...

Nicotine triggers the same brain reward circuitry as opiates

...rain's opiate receptors, but activates the natural opioid reward pathway in the brain. The researchers, led...activation. Also, mutant mouse strains lacking the opioid receptor did not show an increase in CREB activity when they received nicotine. The researchers als...

Opiate cocktail may spare cells from morphine's dark side

...mall doses of two versions of methadone, a related opioid drug, significantly reduced both tolerance and dep...pecialized protein on the surface of cells, the mu opioid peptide receptor, or "MOP" receptor. MOP receptors are also activated by other opioid drugs and by e...

Prescription pain patch abuse blamed for increase in deaths

...le dying from an overdose of the drug fentanyl, an opioid 100 times more potent than morphine, rises. Addicts are misusing a clear patch that transfers a controlled dose of fentanyl through the skin into the bloodstream over the course of a few days, UF experts say. The adhesive patch is typically prescrib...

Hepatitis C complicated by morphine withdrawal

...e withdrawal, which is a common recurring event in opioid users. Chuan-Qing Wang and colleagues examined ...sessed the effects of using naloxone, to block the opioid receptors, in conjunction with drug removal, i.e. precipitated morphine withdrawal (PW). To measure...

Brain differences could explain why males and females experience pain relief differently

...ter degree in males than in females. Morphine ?an opioid drug or narcotic - reduced the response of this ci...dicine and the American Pain Society indicate that opioid drugs or "narcotics", such as morphine, are essential in the management of chronic pain. However, t...

Pleasure and pain: Study shows brain's 'pleasure chemical' is involved in response to pain too

...udy individual variation in the effects and use of opioid painkiller drugs among people with chronic pain. ...

New brain-chemistry differences found in depressed women

...within the brain -- specifically in the endogenous opioid system that is a central part of the brain's natur...hese differences in the response of the endogenous opioid system. Some women, but not others, with major depression, showed exaggerated responses in this syst...

Long-term narcotics use for back pain may be ineffective and lead to abuse

...ine, who also found that behaviors consistent with opioid abuse was reported in 24 percent of cases. "Pati...ic back pain commonly request pain medication, and opioid medications are used despite the concerns clinicians have with patients developing an addiction to t...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...increase by about one thousand times the number of opioid receptors expressed on the surfaces of nerve cells that carry pain messages back and forth between an osteoarthritic jaw joint and the spinal cord. Thus, nerve cells involved in pain transmission, with so many more receptors on their surfaces, became...

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