Production of key Alzheimer's protein monitored for first time in humans
... According to the authors, the new testing process opens a valuable window into the genesis of Alzheimer's disease that, in addition to helping scientists better understand the origins of the condition, will likely help them improve its diagnosis and treatment. The scientists' results will be published o...New pathways for autoimmune treatment identified
... College of Georgia researchers say. This finding opens new pathways for treating or preventing APS1, or autoimmune polyglandular syndrome type 1, and potentially other autoimmune diseases as well, researchers report in the June issue of Nature Medicine. "The body should maintain a balance between killi...First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown
...ical signaling between mitochondria and myofibrils opens a new possibility to search for drugs capable of increasing cardiac contractility," Veksler said. *Presentations: The paper, "Direct mechanical communication between mitochondria and nucleus in cardiac cells," was chosen to be part of the "Physiolog...Hepatitis C therapy: Inhibiting newly discovered microDNA molecule
...mal RNA that interacts with its target 5' NCR, and opens an interesting possibility that other viral 5' NCRs are similarly targeted by different miRNAs. ...Protein found to control tumor growth in certain breast cancers
...cate mechanisms of this previously unknown pathway opens up the potential for future development of novel therapeutics, and will hopefully stimulate researchers to take a fresh look at the Nod1 protein." In the study, researchers looked at a number of biological processes where Nod1-dependent apoptotic...Study may help slay 'Yellow Monster'
...eat deal and not just in the realm of science. "It opens up doors and windows everywhere else," she said, noting that the work has raised her awareness about mine safety, tribal issues and reclamation efforts. "When we first heard of the yellow monster, it was scary and not much was understood until the r...Molecular force field helps cancer cells defend against attack
...te, and, when over-expressed or hyperactivated, it opens a molecular gate that allows tumor cells to detach and metastasize," Frisch said. "The Cance lab's new observations on the VEGFR3-FAK interaction are both of interest for understanding the functions of these two pivotal molecules in cell behavior, as...Scientists identify molecular structure of key viral protein
...n of the viral and cellular membranes. The protein opens the inside of the virus to the inside of the cell, delivering the viruses genetic information into the cytoplasm of the cell to infect it." In the process the protein moves from its first folded state, the metastable state (pre-fusion), to its secon...Hap1 protein links circulating insulin to brain circuits that regulate feeding behavior in mice
...esearch in La Jolla, further stated, Òthe new work opens up additional targets for obesity research. For example, a drug that decreases Hap1 in the hypothalamus would decrease the electrical drive that underlies eating behavior, resulting in weight loss and potentially longer lifespan.Ó ......ng snap that thrusts them into an egg. The finding opens a new research pathway that the researchers said could help scientists both recognize new forms of male infertility and design new contraceptives to thwart sperm entry into the egg. What's more, they said, the exquisitely delicate analytical techniq...It's in the genes: Study opens door to new treatment of the blues
...se it gives us an animal model of the disorder and opens up new areas of study." In the experiment, the researchers subjected mice to daily bouts of social threats and subordination by aggressive rodents and continuous sensory contact with the aggressors for 10 days. Afterward, the defeated mice avoided a......search Division, Smithville, Texas. "The discovery opens up a new field of inquiry into the role of DNA shape in genomic instability and cancer." Imagine untwisting the DNA ladder and then winding it up the other way. The result is a twisted mess with segments jutting out left and right, and the all impor...Neuroscientists discover new cell type that may help brain maintain memories of smells
...elp the brain maintain memories of smells and also opens a new approach to understanding the basis of memory impairments in Alzheimer's disease. Their paper appears in the March 16 issue of the journal Neuron. It was surprising to the researchers that no one had studied these cells before given the refer...Wisconsin scientists find a way to make human collagen in the lab
...agen in the lab. The work is important because it opens a door to producing a material that can have broad use in medicine and replace the animal products that are now used but that can also harbor pathogens or spark undesirable immune responses. What's more, the new work may also lay the foundation for a...Sea coral's trick helps scientists tag proteins
... Russian Academy of Sciences in Moscow. "This tool opens new possibilities for studying protein and organelle dynamics in living cells, cell migration during embryogenesis, inflammation, and other pathological and normal processes," he said. Unlike other green-to-red fluorescent markers, Dendra can be act...Front-line immune cells mature in four stages, study shows
...on of Hematology-Oncology. "Still, we believe it opens new doors to manipulating the human immune system to our benefit, and we're working on that right now," says Caligiuri, who is also professor of internal medicine, of molecular virology, immunology and medical genetics and of veterinary biosciences. ...Stanford study of owls finds link in brain between sight and sound
...als and different parts of the brain. "This paper opens the floodgates for studying a wide range of species," Knudsen said. "The fundamental mechanisms are probably going to be the same in all vertebrates, as even frogs and fish have gaze control." All animals have to be able to attend to certain stimuli ...Protecting endangered species helps reduce poverty
... Parties to the Convention on Biological Diversity opens today in Curitiba, Brazil, WWF urges the CBD and member governments to integrate species conservation work into efforts to alleviate poverty. "Now's the time to recognize the strong connections between sustainable economic development, a healthy en...Researchers use dirt to stay one step ahead of antibiotic resistance
... by other soilbacteria. Understanding this process opens up a new avenue for findingnew therapies to prevent and treat antibiotic resistance in a clinicalsetting. ...Environmental metagenomics diagnosing extreme environments, tapping opportunities for clean energy
...the environment in question, an informative window opens onto that important and underutilized portion of the biosphere. "Termites eat wood, but they can't extract energy from the complex lignocellulose polymers within it," Rubin says. "These polymers are broken down into simple sugars by fermenting micro...