Scientists clone mice from adult skin stem cells
...ear transfer procedure, Li took unfertilized mouse oocytes and replaced the nucleus of each oocyte with a nucleus from these adult skin stem cells. A main hurdle in nuclear transfer with adult cells has been its efficiency ?out of a hundred attempts, only a handful may succeed ?with reported success rate...Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment
...emonstrated the disruptive action of SMase in frog oocytes (egg cells) engineered to place CFTR in their membrane. These oocytes are an experimental tool that allows the researchers to assess the flow of ions across the membrane ...Heavy smoking cuts women's chance of pregnancy -- even with donated oocytes
...pact of smoking in women who have received donated oocytes ?the situation that allows the most objective asse...hat we see this result in a situation in which the oocytes were donated by other women demonstrates that cigarette smoking negatively affects the receptiveness...Fertility hope as study shows eggs survive in older ovaries
...at female mammals are born with a finite number of oocytes (eggs). Two years ago, international researchers... In the mammalian ovary, reproductive cells called oocytes (eggs) develop within ovarian follicles. In humans, the eggs are believed to die off from late in fo...With few factors, adult cells take on character of embryonic stem cells
...r nuclear contents into egg cell precursors called oocytes or by fusion with embryonic stem cells, earlier studies showed. Those findings provided evidence that unfertilized eggs and embryonic stem cells contain factors that can confer pluripotency to differentiated cells, Yamanaka said. "We hypothesized...New egg freezing technique offers hope to hundreds of women
... more than 90% survival rate for the freeze-thawed oocytes and a high pregnancy rate of nearly 42% after the oocytes had been fertilised and implanted in the women. This pregnancy rate is practically the same as the r...FSU biologists uncover mechanisms that shape cells for better or worse
...ers the development of cell polarity in Drosophila oocytes (unfertilized fruit fly eggs) also are known playe...ery in the biological model provided by Drosophila oocytes has broad implications in humans, where, for example, neurons in the brain are designed, or polarize...With few factors, adult cells take on character of embryonic stem cells
...r nuclear contents into egg cell precursors called oocytes or by fusion with embryonic stem cells, earlier studies showed. Those findings provided evidence that unfertilized eggs and embryonic stem cells contain factors that can confer pluripotency to differentiated cells, Yamanaka said. "We hypothesized...Component in soy products causes reproductive problems in laboratory mice
... develop abnormally. The researchers explain that oocytes that remain in clusters are less likely to become ...group were single We think genistein inhibits the oocytes or egg cells from separating apart," said Wendy Jefferson, Ph.D. of NIEHS and lead researcher on the...Israeli scientists successfully transplant frozen-thawed ovaries in sheep
...hole frozen and thawed ovaries in sheep, retrieved oocytes from these ovaries and triggered them in the labor...howed that the ovaries in the two sheep from which oocytes were recovered were still functioning normally three years later. Lead author Dr Amir Arav, senior...Researchers devise new technique for creating human stem cells
... nuclei of adult cells, called somatic cells, into oocytes in which scientists have removed the nuclei. The researchers said that -- while the technique might one day be used along with SCNT, which involves the use of unfertilized human eggs -- technical hurdles must be cleared before the new technique sees...Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005
...occurs in humans. However, there are few human MII oocytes available for research because almost all that are... treatment are used to treat the patient. Immature oocytes are not used routinely for treatment at present, and so any that are retrieved can be donated for re...Scientists succeed in cloning human embryos from eggs matured in the lab
...occurs in humans. However, there are few human MII oocytes available for research because almost all that are... treatment are used to treat the patient. Immature oocytes are not used routinely for treatment at present, and so any that are retrieved can be donated for re...Human Eggs Can Develop From Ovarian Surface Cells In Vitro
...ent research of adult human ovaries has shown that oocytes and granulosa cells (the layer of small cells that...se mature eggs. However, definitive proof that new oocytes may develop in adult human females will be if they can be found to differentiate in vitro from OSE c...SuperLigands - a database of ligand structures derived from the Protein Data Bank
...led "somatic cell nuclear transfer" or SCNT. Next, oocytes with the patient's genetic material were allowed t...ea and colleagues replaced the nuclei from donated oocytes with nuclei from skin cells from male and female patients, ranging in age from 2 to 56, who had spin...Scientists generate patient-specific stem cells, Science study says
...led "somatic cell nuclear transfer" or SCNT. Next, oocytes with the patient's genetic material were allowed t...ea and colleagues replaced the nuclei from donated oocytes with nuclei from skin cells from male and female patients, ranging in age from 2 to 56, who had spin...Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment
...scous glassy state. Research so far has used mouse oocytes but U-M expects to make the technology available in the clinic soon. "With traditional slow-freeze techniques, just over half the eggs survive the thawing process. Using vitrification, we are getting 98 percent survival. For a woman with cancer, the...