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Tag: "onset" at biology news

Study reveals dramatic difference between breast cancers in US and Africa

...dence of breast cancer than Caucasians but earlier onset and worse prognosis. African American women under the age of 35 have a 50 percent greater risk of developing breast cancer than Caucasians. This risk levels off by around age 50 and African Americans over 50 have less risk than Caucasians. Most of t...

Red delicious, Northern Spy apples have most antioxidants, chemists find

...on cells and tissues, appear to play a role in the onset of heart disease and prostate, colon and other cancers. Polyphenols ?phytochemicals that act like astringents ?are major sources of antioxidants in apples, but which polyphenols are most active in the fruit has perplexed scientists. Tsao and his col...

Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma

...ed that specific genetic changes may accompany the onset and progression of the disease. Dr. Andrew Holloway of the Peter MacCallum Cancer Centre said his team will work in conjunction with colleagues at The University of Western Australia, using Agilent's CGH microarray to provide a more thorough underst...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

... and motor function." Children transplanted after onset of symptoms do stabilize but exhibit minimal neurologic improvement, said Maria Luisa Escolar, MD, of UNC-CH, whose team assessed the neurological, cognitive and physical development of each child with Krabbe Disease before and after transplant. Esc...

Important discovery about second most fatal cancer

...thological and molecular features: # Early age at onset # More common in females # More common in right side of colon # Little evidence of tumour immunity # Frequent mutation of an oncogene called BRAF (also mutated in cancer of thyroid, ovary, and melanoma) # Frequent DNA methylation (chemical change whi...

Human Eggs Can Develop From Ovarian Surface Cells In Vitro

.... This may result in a 10- to 12-year delay of the onset of natural menopause. Also, these ovarian stem cells could be used to generate several cell types used in stem cell research, and fertilized eggs produced in this way could produce cells capable of giving rise to embryonic stem cells for use in resea...

U. Iowa researchers improve Huntington's disease symptoms in mice

...se progression is delayed or possibly even disease onset is prevented." It may even be the case that a partial reduction of toxic protein levels allows the brain cells' machinery to "catch up" with the disease-causing protein and clear out the damage caused by the mutant protein. The genetically engineer...

Active Vaccine Prevents Mice From Developing Prion Disease

...t can significantly delay and possibly prevent the onset of a brain disease in mice that is similar to mad cow disease. The new findings, published online this week in the journal Neuroscience, could provide a platform for the development of a vaccine to prevent a group of fatal brain diseases caused by un...

Deep sea algae connect ancient climate, carbon dioxide and vegetation

... dioxide levels, such as corn and sugarcane. "The onset and stabilization of ice sheets at the same time as a decline in carbon dioxide illustrates the importance of atmospheric carbon dioxide as an agent of both climate and biological change," Pagani said. Collaborators were Brett Tipple from Yale, Jame...

Invasive parasite destroying fish species

... dioxide levels, such as corn and sugarcane. "The onset and stabilization of ice sheets at the same time as a decline in carbon dioxide illustrates the importance of atmospheric carbon dioxide as an agent of both climate and biological change," Pagani said. Collaborators were Brett Tipple from Yale, Jame...

Stem cells grown in lab mirror normal developmental steps

... dioxide levels, such as corn and sugarcane. "The onset and stabilization of ice sheets at the same time as a decline in carbon dioxide illustrates the importance of atmospheric carbon dioxide as an agent of both climate and biological change," Pagani said. Collaborators were Brett Tipple from Yale, Jame...

A protein in the eye may prevent immune response and protect eyes from disease

...e the ability to prevent the usual immune response onset when confronted with foreign invaders such as bacteria. Without this special reaction, the eye's delicate tissue would be destroyed by inflammation and the gastrointestinal tract could not tolerate the ingestion of food. The F4/80 molecule (also know...

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

...the brain to mount another response in case of the onset of another possible stressor. The endogenous cannabinoids may serve to link the stress response with other neuroendocrine functions controlled by the hypothalamus, such as feeding. Di says that the "actions of the endocannabinoids on the synaptic ci...

Secrets to antibody's success against West Nile Virus surprise scientists

...tudies of dengue virus and may be important to the onset of dengue hemorrhagic fever. This theory suggests that dengue and other viruses may have developed tricks that let them reproduce inside macrophages, the immune cells that normally consume and destroy any object that they find covered in antibodie...

UIC developing drug for SARS

...t replication of the virus peaks 10 days after the onset of fever," said Michael Johnson, director of the Center for Pharmaceutical Biotechnology in the UIC College of Pharmacy and the study's principal investigator. "By administering protease inhibitors early, when feverish symptoms have started, the drug...

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models

...luble protein clumps in the brain, can precede the onset of dementia by many years. These plaques are formed when enzymes cleave the amyloid precursor protein (APP) releasing the toxic beta amyloid fragments that clump together to form the sticky plaques. One of the enzymes doing the cleaving is called bet...

Use of high hydrostatic pressure to inactivate Hepatitis A virus in oysters studied

...muscle aches, and abdominal pain, coupled with the onset of jaundice, a yellowing of the whites of the eyes, and dark urine. The disease generally runs its course in two months, but can linger as long as six. While survival rates for Hepatitis A are above 99 percent, the disease can be very dangerous for i...

Huntington's cure in flies lays groundwork for broader treatment approaches

... that at least 20 genes have a role to play in the onset of seizures, and dozens more may be involved. Though many might argue for directing research dollars to the continued search for epilepsy genes, Yin believes funding agencies should now consider investing in the search for these "superhighways" of ge...

Stem cells bring fast direct improvement, without differentiation, in acute renal failure

...aracrine actions are elicited early and late after onset of ARF The study said it "provides the first clear evidence that therapy with MSC affords significant renoprotection in rats with ischemic/reperfusion (I/R) ARF. Animals infused with MSC either immediately or 24 hours after reperfusion had significa...

Suppressing growth hormone in early adulthood may prevent cancer

...mpounds beginning in early adulthood may delay the onset or progression of several types of cancer, researc...entative measures to lower plasma IGF-1 before the onset of disease, especially in high-risk people. In a previous study, rats with high levels of growth ho...

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