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Tag: "onset" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...productive system in common with the human's. The onset of puberty becomes official when gonadotropin-releasing hormone (GnRH) is secreted and sets off a chain reaction of chemical messages. Inside the hypothalamus, nerve cells release GnRH in a 'round-the-clock,' pulsatile fashion. With each secretion, t...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...heprincipal type of DNA damage responsible for the onset of skin-tumordevelopment. The researchers' finding...e DNA(mutations) that ultimately can result in the onset of skin cancer.Thus far it was not clear how the two major types of UV-induced DNAlesions ?cyclobuta...

Growth in the sea comes down to a struggle for iron

...t global climate, perhaps even contributing to the onset of ice ages. Martin died in 1993 just as tests of his ideas were getting underway, but scientists have embarked on a series of experiments in three major areas of the world's oceans. "The three areas are the Southern Ocean around Antarctica, the equ...

Scientists detect probable genetic cause of some Parkinson's disease cases

...ts have longsuspected genetics plays a role in the onset of the disease. In thesestudies, the investigators... of thedisease increases with age, with an average onset at about 60 years....

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

... Dr. McIntoshpointed out some "tantalizing facts": onset of Kawasaki disease isoften preceded by a respiratory syndrome; both the disease andrespiratory coronavirus infections are seasonal, peaking in the winterand spring; recent studies have described a powerful immune response inthe respiratory tract and...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...e period of drug treatment that isrequired for the onset of telomere crisis and reduce the potential riskof acquired drug resistance, " writes Dr. Seimiya.Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, and TakashiTsuruo: "Tankyrase 1 as a target for telomere-directed molecular cancertherapeutics"....

GATA: a graphic alignment tool for comparative sequence analysis

...e period of drug treatment that isrequired for the onset of telomere crisis and reduce the potential riskof acquired drug resistance, " writes Dr. Seimiya.Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, and TakashiTsuruo: "Tankyrase 1 as a target for telomere-directed molecular cancertherapeutics"....

Learning to fight an adversary that won't stay down

... drugs so as to avoid overuse and the accompanying onset of resistance. "There are a relatively small number of antibiotics that have come out that are new, and some of them are very potent and act against most resistant strains," he says. "But the clinicians rightly try to keep these things in reserve fo...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...es one strategy to halt Parkinson's disease at its onset and another strategy to treat the devastating side effects that occur when treating the disease in its later stages. By inserting corrective genes into the brain, scientists studying small monkeys called marmosets prevented brain damage by producing...

Discovery Could Lead To Novel Approaches In HIV Treatment

...und that,already in the first months following the onset of infection, thymicfunction is decreased. Such a decrease results in a loweredT-lymphocyte production by the thymus.These findings pave the way to the development of novel immunotherapiesof HIV-infected individuals. Such immunotherapies could be als...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...is revealed that the Foxl1 deficiency affected the onset of tumor formation, accelerating them to arise in 1/3rd of the normal time. The authors examined the integrity of the APC gene in these tumor cells and found that more than ninety per cent of the tumors had lost the normal copy of the APC gene and no...

Gene therapy for Parkinson's disease moves forward in animals

...es one strategy to halt Parkinson's disease at its onset and another strategy to treat the devastating side effects that occur when treating the disease in its later stages. By inserting corrective genes into the brain, scientists studying small monkeys called marmosets prevented brain damage by producing...

Chemists identify key gene in development of type 1 diabetes

...the destruction of the pancreas and the subsequent onset of type 1 diabetes. The disease is much less common than type 2 diabetes, formerly known as adult onset or non-insulin-dependent diabetes, which is often associated with obesity. "We've shown that the MI...

Vascular structure and function improve with diet and exercise

... a measure of end organ damage often following the onset of LVDF abnormalities. The brachial (arm) and carotid (neck) arteries were tested for intima-media thickness and arterial distensibility. Both reflect the health of the blood vessels. The thicker and less distensible (elastic) the arteries are, the ...

Towards precise classification of cancers based on robust gene functional expression profiles

...the destruction of the pancreas and the subsequent onset of type 1 diabetes. The disease is much less common than type 2 diabetes, formerly known as adult onset or non-insulin-dependent diabetes, which is often associated with obesity. "We've shown that the MI...

WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas

...malaria cases but does have dengue cases. With the onset of the rainy season, particularly in Indonesia and Sri Lanka, a rise in the cases can be expected at this time of the year. Indonesia suffered a major dengue outbreak last year. This year too, many cases have been reported in Jakarta, since December...

Marburg haemorrhagic fever in Angola update

...idence that people can spread the virus before the onset of symptoms. Shortly after symptom onset, patients become rapidly and visibly very ill WHO is optimistic that the outbreak can be controlled if present activities continue with sufficient vigour. All the essential containment measures are being appl...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...l sclerosis (ALS), substantially delaying both the onset and the progression rate of the fatal motor neuron... neurons and neighboring glial cells, and both the onset and the rate of progression of the disease in the treated mice were substantially reduced. In additi...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

... and motor function." Children transplanted after onset of symptoms do stabilize but exhibit minimal neurologic improvement, said Maria Luisa Escolar, MD, of UNC-CH, whose team assessed the neurological, cognitive and physical development of each child with Krabbe Disease before and after transplant. Esc...

Genetic defects give the immune system the green light to attack the pancreas

...sulin-producing beta cells.?This first step in the onset of type 1 diabetes is called insulitis. Later in life, within weeks or even years, full-blown type 1 diabetes emerges. An estimated 1 million people in the United States have type 1 diabetes. Their pancreatic beta cells can no longer make insulin. W...

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