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Tag: "one" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...e in boys. As such, this research begins to answer one of the most vexing questions about human developme...kisspeptin being administered to male monkeys, LH, one of the hormones stimulated by GnRH secretion, was no longer dormant, with levels 25-times higher tha...

Chemists create 'Superbowl' molecule; May lead to better health

In a development that could one day score a touchdown for better health, chemists ...blished in the Dec. 29 print issue of the journal, one of the peer-reviewed publications of the American Chemical Society, the world's largest scientific s...

DNA Molecules Used To Assemble Nanoparticles

...e clusters of two different functional dendrimers, one designed for imaging and the other for targeting c...bell shaped two-dendrimer complexes with folate on one end and fluorescence on the other end. Folate receptors are over-expressed on the surface of cancer...

Wisconsin scientists grow critical nerve cells

...e rolling of an eyeball. The new development could one day help victims of spinal-cord injuries, or pave ...otor neurons, Zhang believes, may be that they are one of the earliest neural structures to emerge in a developing embryo. With the ticking clock of develo...

Association of herpesvirus with lung disorder questioned

...erformed two types of tests in the tissue samples, one to detect an antigen associated with HHV-8, the other to detect HHV-8 DNA. Both tests failed to detect either the antigen or the DNA in any of the 22 samples from the two groups with some form of pulmonary hypertension, whereas the antigen was detect...

Man and mouse share genome structures

...omen's Hospital and Harvard Medical School. "Every one of our cells has the same genome, yet is completely different. Muscle cells are different from neurons. They are different because different genes are on." Many scientists believe changes in the regulatory scaffolding surrounding the genome may be a...

Jump-starting T Cells In Skin Cancer

... vaccinated with a tumor antigen called MAGE-3. In one patient whose tumor regressed after vaccination, the authors found significantly more T cells specific for non-vaccine tumor proteins than were detected before vaccination. Vaccine-specific T cells, on the other hand, became detectable but did not ex...

Molecular biology fills gaps in knowledge of bat evolution

...rch helps fill gaps in the evolutionary history of one of the most diverse group of mammals on earth and the only mammals capable of powered flight. The fossil record alone left bat evolutionary history about 61 percent incomplete, according to Springer. Bats play a major ecological role as plant pollina...

A new mechanism of regulating RNA degradation

...arnered significant attention in recent years, and one that has the potential to produce a new set of too...ommon fruit fly Drosophila are understood. "But no one knew what Staufen1 did in human cells," said Maquat, even though its presence in mammalian cells has...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...arnered significant attention in recent years, and one that has the potential to produce a new set of too...ommon fruit fly Drosophila are understood. "But no one knew what Staufen1 did in human cells," said Maquat, even though its presence in mammalian cells has...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...blood samples taken from pairs of sisters in which one sister had been diagnosed with breast cancer and the other had not. They found that DNA repair capacity was lower in breast cancer patients than in the control subjects. Deficient DNA repair capacity was associated with a twofold increase in the ris...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...Sweden, and several hospitals in Finlandas well as one hospital in Reykjavik provided the project with DNAsamples and diagnostic information from SLE patients....

Researchers discover way to make cells in the eye sensitive to light

...rial College London and Charing CrossHospital, and one of the papers authors, comments: "It is quiteremar... Rob Lucas, from the University of Manchester, and one of the paper'sauthors, adds: "The discovery that melanopsin is capable of makingcells photosensitive...

Protein discovery could unlock the secret to better TB treatment

...e bacteria causing TB in patients are resistant to one or more drugs and one per cent show multidrug resistance. Left untreated, a person with infectious TB of the lungs infects...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

...U-Boulder biologists led by Professor Norman Pace, one ofthe world's leading experts on molecular evoluti...resting inthe context of microbiology because it's one of the few times we'vebeen able to study microbes to get information on an entire ecosystem.That's n...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

... Japan has discovered that having a double dose of one protein is sufficient to change the normal balance...equence overlaps the region that usually shuts off one copy of IGF2. As a result, these mice lack H19 and have double IGF2. To isolate the effect of the e...

Columbia research lifts major hurdle to gene therapy for cancer

...ty MedicalCenter have discovered a way to overcome one of the major hurdles ingene therapy for cancer: its tendency to kill normal cells in theprocess of eradicating cancer cells.In a new study published in the Jan. 25 issue of the Proceedings of theNational Academy of Sciences (PNAS), the researchers de...

Dysentery uses 'sword and shield' to cause infection

... Christoph Tang, from Imperial College London, and one of the researchers, comments: "This is the first description of bacteria able to use this 'sword and shield' approach, showing how dysentery is able to infect the body so effectively. We have shown why the bacteria can avoid being destroyed by the bo...

Novel technology detects human DNA mutations

...omplex asit requires sifting through the more than one billion base pairs of DNA to find a particular bas... both are mutant or normal) or heterozygous (i.e., one is mutant, one is normal) ?the most critical step in correlating the SNP with a disease or drug sens...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...icovaginal lavage (CVL) fluid collected before and one hour after administration of a single intravaginal dose of PRO 2000 gel or a matched placebo gel. CVL specimens were tested for their ability to prevent HIV and HSV infection of susceptible human cells in culture. Levels of inflammatory cytokines wer...

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