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Tag: "oncology" at biology news

Mayo Clinic collaboration discovers protein amplifies DNA injury signals

...t mutations," says Junjie Chen, Ph.D., Mayo Clinic oncology researcher and leader of the Mayo Clinic team. "This is just one mechanism involved in communicating injury to the repair processes, but it's an important start to understanding how we might one day design new treatments that help this repair system ...

U-M scientists identify major psoriasis susceptibility gene

...Ph.D., a professor of dermatology and of radiation oncology in the U-M Medical School and the Ann Arbor VA Healthcare System. "It's as if you are pushing a shopping cart down the aisle at the grocery store and putting genes in your cart," Elder adds. "There are several different brands of each gene on the sh...

Hopkins researchers discover genetic switch that turns off an oxygen-poor cell's combustion engine

... M.D., Ph.D., professor of medicine, cell biology, oncology and pathology, and vice dean for research at the Johns Hopkins University School of Medicine. Dang says the switch may be a target for cancer drugs because a cancer cell's survival depends on it to convert glucose to lactic acid through glycolysis ...

Weighting cancer drugs to make them hit tumors harder

...department of biomedical engineering and radiation oncology at Duke measured the tumor permeability, penetration and accumulation of various macromolecular weights in mouse tumors. The drug carrier they studied was dextran, essentially a chainlike string of sugar molecules. By measuring a range of dextran mo...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...e. According to Lynn Hartmann, M.D., professor of oncology at the Mayo Clinic College of Medicine in Rochester, Minn., about one million women a year have a breast biopsy with benign findings (sometimes called benign breast disease). One form of benign breast disease, atypical hyperplasia, or atypia, is char...

New device could cut chemotherapy deaths

...Avon, Somerset and Wiltshire Cancer Centre and the oncology team at the Royal United Hospital for the design and development of these drug delivery vehicles. This team includes Dr Ed Gilby, one of the most experienced consultant oncologists, surgeons Mr Nicholas Johnson and Mr Kenneth Jaaback, clinical trials...

Amgen introduces comprehensive financial assistance programs for cancer patients

...en. "Our goal is to create the most comprehensive oncology access program in the industry, and we are startin...hed patient assistance program that provides Amgen oncology medicines at no cost to qualifying uninsured patients. Available to patients with household adjuste...

Major cancer study aims to identify protein markers for early-stage disease

...f laboratory medicine, and co-leader of the breast oncology program at the UCSF Comprehensive Cancer Center, and Bradford W. Gibson, PhD, a professor and director of chemistry at the Buck Institute for Age Research and UCSF adjunct professor of pharmaceutical chemistry. The team also includes key co-investi...

Pure carbon nanotubes pass first in vivo test

...co-author Dr. Steven Curley, professor of surgical oncology and chief of gastrointestinal tumor surgery at M. D. Anderson. "We are particularly pleased that the fluorescent effect remains intact in our application, because this makes it easier to see where the nanotubes end up, and it opens the door to some e...

Getting to the heart of the heart

...School and also chairs the department of pediatric oncology at Dana-Farber Cancer Institute. He and Wu are also members of the Harvard Stem Cell Institute. "Previously, it had been thought that each cell type in the heart had a different origin. Now, it's pretty clear that some have common origins," Orkin a...

Mars mission Risk 29: Scientists research ways to reduce radiation-induced brain damage

.... Britten, Ph.D., associate professor of radiation oncology and biophysics at Eastern Virginia Medical School (EVMS) in Norfolk, Va. "That eventually could help patients dealing with conditions that cause dementia." The idea of a manned mission to Mars has captured the imagination for decades, and gained fo...

Report calls for improved monoclonal antibodies against solid tumors

...eading experts in monoclonal antibody research for oncology offers a conceptual framework for future research in the design of antibody therapies against solid tumors. Writing in the January 15, 2007 issue of CANCER ( http://www.interscience.wiley.com/cancer-newsroom ), a peer-reviewed journal of the American...

U-M researchers use nanoparticles to target brain cancer

...tulla, Ph.D., professor of radiology and radiation oncology at the U-M Medical School and professor of environmental health sciences at the School of Public Health. Treating brain tumors is traditionally difficult because of the blood-brain barrier, which prevents harmful substances from traveling through...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

...t therapeutically," says Bill Sugden, professor of oncology who has studied EBV for more than 30 years. "Our goal is to develop a successful anti-viral, anti-tumor therapy for all EBV-positive tumors." In the current study, Sugden and his colleague of 20 years, Wolfgang Hammerschmidt, now based at the German...

'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance

...k done in his lab that he, along with professor of oncology Richard Burgess, started a company called ConjuGon - "because you conjugate and it's gone!" -- to develop the technology and ultimately bring it to human trials, which are currently planned for 2007 or 2008. A patent for his discovery has just been ...

Preliminary study finds holographic imaging system promising for cancer treatment planning

...of medical physics for the department of radiation oncology at Rush. "The preliminary data demonstrates that Perspecta has a significant advantage over current 2D radiation planning systems. We are looking forward to an expanded study with a larger number of patients to determine the true potential of this sy...

Cloned mice created from fully differentiated cells, a milestone in cloning research

...author Dr. Cheng, associate professor of radiation oncology at the University of Pittsburgh School of Medicine and director of stem cell biology and co-leader of the cancer stem cell program at the University of Pittsburgh Cancer Institute. Previous attempts by scientists to produce animal clones directly fr...

Unique tomatoes tops in disease-fighting antioxidants

... Clinton, an associate professor of hematology and oncology and human nutrition; Nuray Unlu, a former postdoctoral researcher in food science; and Torsten Bohn, a former postdoctoral fellow in food science at Ohio State. ...

Lab research may one day lead to cancer treatment using patient's own immune cells

...al Center. Julian A. Kim, M.D., chief of surgical oncology at UH Ireland Cancer Center, has received a $660,000 grant from the National Institutes of Health for a five-year study that hopes to lead to new treatments using a set of immune cells, called T cells, to fight skin cancer (melanoma) and breast cance...

Sunshine pill for prostate cancer in 2009

...uld be significant,' says Nick James, professor of oncology at the University of Birmingham. In the phase II trials, Asentar significantly improved survival rates, 9 months over patients taking chemotherapy drugs (taxotere) alone. 'On average, patients in the advanced stage of the disease survive about 18 mo...

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