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Tag: "oncogenic" at biology news

New binding target for oncogenic viral protein

...40) accomplishes this task by producing the highly oncogenic large T antigen. This protein corrupts the cellula... Fbw7 is mutated in cancers, deregulation of these oncogenic Fbw7 targets is thought to contribute to cancer. SV40 T antigen contains a motif that mimics the des...

Engineered skin offers clues to melanoma development

...the journal Nature Genetics, offering clues to the oncogenic potency of several genes implicated in the develop...anoma was observed as early as one month after the oncogenic combination was introduced. The tumors demonstrated aggressive local invasion but did not metastasiz...

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

...the journal Nature Genetics, offering clues to the oncogenic potency of several genes implicated in the develop...anoma was observed as early as one month after the oncogenic combination was introduced. The tumors demonstrated aggressive local invasion but did not metastasiz...

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

...the journal Nature Genetics, offering clues to the oncogenic potency of several genes implicated in the develop...anoma was observed as early as one month after the oncogenic combination was introduced. The tumors demonstrated aggressive local invasion but did not metastasiz...

Researcher uncovers details of how cancer spreads

...rchers used a protein called v-Src derived from an oncogenic virus, which has the ability to transform a normal cell into one with many features resembling those found in cancer cells. While this virus has not been found in humans, it does lead to tumor growth in chickens and created cancerous cells in the cul...

New human retrovirus originated in mice

... likely to clear it. Clearly XMRV is not a classic oncogenic virus." Nevertheless, said Ganem, an indirect link to cancer cannot be ruled out, since "in cancer research these days, there is a lot of interest in the stroma as the soil in which cancer arises." He added that the chronic inflammation from infecti...

Gene first linked to rare disease may trigger skin cancer, other tumors

...some forms of leukemia. That modification bars the oncogenic protein's entry into the cell nucleus, the central command center and storehouse for DNA, where it would otherwise drive the uncontrolled increase in cell numbers characteristic of tumor growth. The researchers first showed that mice lacking CYLD we...

Higher risk for cervical cancer seen among women infected with multiple HPV types

... 58, which the new study discovered to be far more oncogenic than others when found in co-infections with other HPV types. The study's findings suggest HPV 58 should be one of the targets of the next generation of cervical cancer vaccines. Indeed, the scientists discovered that the higher risk associated wit...

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