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Wisconsin scientists grow critical nerve cells

... stage of motor neuron development to another. But once past a certain point, Li found that the cells kept veering off toward different cellular destinies. After hundreds of unsuccessful variations of growth factors and morphogens, Li was struck by an idea: Why not apply a chemical known to be necessary f...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...nd that E. histolytica infection occurred at least once in 80 percent of 300 children. Over a period of four years, about a third of the children suffered from amebic colitis, an ulceration of the stomach lining. Petri says the genome data will help researchers find more about what makes some people inna...

Timing is everything: First step in protein building revealed

...least hoped -- to see a shift in the colorof light once the RNA was mixed in. Instead, they saw two shifts in thecolor given off. First, there was a slight shift, indicating a smallchange in the distance between eIF1 and its relative, and then a muchlarger shift, indicating a much bigger separation.To pro...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...r now have greater capabilities thancomputers that once occupied an entire room. Similar advances are beingmade in the emerging field of synthetic biology at the University ofHouston, now allowing researchers to inexpensively program the chemicalsynthesis of entire genes on a single microchip.Xiaolian Gao...

Imaging Lymph Nodes with Nanoparticles

...erversassessing data differently.And what is more, once the data have been collected and assessed it ispossible to reconstruct a virtual picture of the patient's lymph nodes,thus potentially allowing accurate surgical removal of the nodes....

U-M scientist to talk about tissue engineering at AAAS

...ngineered cells to the right place, then dissolves once the cells begin to generate to fill in the wound. "In certain kinds of defects, the body cannot heal itself and the body needs a jumpstart," Krebsbach said. To heal a large wound, like that created when a cancerous tumor is removed from the jaw, tha...

Study finds more than one-third of human genome regulated by RNA

...coding regions. In other words,a class of molecule once relegated to the sidelines may be one of theprincipal players in regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously apprec...

The secret lives of whales

...t surviving whale population on earth. It was also once the largest—many times larger than other estimates. This information is critical to current discussions of the International Whaling Commission (IWC) because some argue that the recent surge in minke populations is unprecedented and is hampering the...

NYU researchers simulate molecular biological clock

...coding regions. In other words,a class of molecule once relegated to the sidelines may be one of theprincipal players in regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously apprec...

Researchers reveal the infectious impact of salmon farms on wild salmon

...field study also discovered a new cause for alarm: once the young salmon pass the farm and pick up the sea lice, the migrating school becomes a moving cloud of contagions. Sea lice larvae mature and reproduce on the seaward salmon with each louse producing 300-800 eggs. This second round of lice larvae ca...

New Clues Add 40,000 Years to Age of Human Species

... The Kibish hominids—dubbed Omo I and Omo II—were once entombed in sediments on opposite sides of the Omo River in southern Ethiopia. By applying modern radiometric dating techniques and a careful study of sediments and fossils, the researchers linked the Omo hominids, true Homo sapiens, to a single per...

BRCA1 causes ovarian cancer through indirect, biochemical route

...f ovarian cancer drop precipitously. In addition, once the chemical messenger that's affected has been identified, it will be much easier to diagnose a predisposition to ovarian cancer or pinpoint just who is at risk, simply by measuring the chemical's levels. "The consequence of this finding," Dubeau s...

Poplar trees redirect resources in response to simulated attack

...be available to help the plant spring back to life once the attack has passed. Using the techniques developed at Brookhaven, we now have a way to find out." To simulate an insect attack, the scientists painted a solution of jasmonic acid, a chemical messenger that plants produce in response to various ty...

Essential mangrove forest threatened by cryptic ecological degradation

The recent killer tsunami has highlighted once more the importance of coastline protection. In na...Sri Lankan tradition of freshwater management that once sustained robust irrigation-based civilizations. The researchers show that, increasingly, the magnit...

Scientists develop new color-coded test for protein folding

...sed from 4 to 10, the blue solution turned reddish once again--a strong indication that some cytochrome c molecules had refolded into their original three-dimensional shape. In fact, the experiment showed that, when attached to gold film, cytochrome c can fold, unfold and refold countless times depending ...

DNA Recombination and Repair—A New Twist to RecA Function

...assembly spreads rapidly in the 5'-to-3' direction once the first RecA molecule is loaded onto DNA. At the...e would expect a RecA molecule to dissociate about once every 1.5 seconds, or 40 RecA molecules to dissociate per minute. But this is not what the authors f...

Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed

...r," Waddington said. The West Antarctic Ice Sheet once rested on the bottom of the bay all the way to its "grounding line" at the continental margin in the Ross Sea. However, that ice has retreated substantially in the last 20 millennia, at the same time Siple Dome was thinning. Part of the puzzle has be...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

... because "the fibrils are virtually indestructible once formed," he said. "How all these monomers interact to form these amyloid fibrils is just not known at this point," said Akhremitchev. "And that is why it is such a great challenge. That's what we want to learn." ...

Tiny scaffolding allows stem cells to become working fat cells

... offers important medical potential. While experts once thought a persons number of fat cells was set at birth, they now know individuals can either lose existing fat cells or grow new ones. And aside from the implications for dieting and obesity, a person's population of fat cells has other vital roles. ...

In the migratory marathon, parasitized monarchs drop out early

...g distances, so they can't propagate the infection once arrived at destination. A little-studied outcome of animal migration is whether these long journeys can limit the spread of parasites by weeding out diseased animals. Monarch butterflies in eastern North America fly up to thousands of kilometers fr...

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(Date:4/15/2014)... researchers have previously shown that a genetic pre-disposition to ... a new study, Frank Booth, a professor in the ... link between the genetic pre-disposition for high levels of ... occurs. , For his study, Booth selectively bred rats ... laziness. Booth then put the rats in cages with ...
(Date:4/15/2014)... Western Reserve University dental researchers have found a ... cells from the mouth to study how the ... , By isolating some specialized immune cells (white ... they fight diseases in the mouthor reject foreign ... to learn more about treating and preventing such ...
(Date:4/15/2014)... There are many viral diseases in the world for ... dengue fever, which is spread by mosquitoes in the ... is more familiar in Finland and is easily spread ... small children and the elderly. , Researchers at Aalto ... succeeded in preliminary tests to prevent the spread of ...
Breaking Biology News(10 mins):Genetic pre-disposition toward exercise and mental development may be linked 2New method isolates immune cells for researchers to study how they ward off oral diseases 2Nanocrystalline cellulose modified into an efficient viral inhibitor 2
(Date:4/16/2014)... Celldex Therapeutics, Inc. (NASDAQ: CLDX) announced today that ... CDX-1401 in solid tumors, including long-term patient follow-up, ... (Vol 6 Issue 232). The data demonstrate ... of clinical benefit in patients with very advanced ... to better outcomes on subsequent therapy with checkpoint ...
(Date:4/16/2014)... According to a new study, endoscopists, recommendations for ... to two small polyps are consistent with guideline recommendations ... an appropriate target for quality indicators. This is the ... guidelines for timing of repeat colonoscopy after one to ... average-risk patients. The study appears in the April issue ...
(Date:4/15/2014)... diabetes and pre-diabetes in the United States have nearly ... Hopkins Bloomberg School of Public Health, with obesity apparently ... that the burden of the disease has not hit ... blacks, Hispanics and the elderly. , According to new ... the Annals of Internal Medicine , diabetes increased ...
(Date:4/15/2014)... decades-old medical mystery and in the process have found ... which kill about 1.5 million people a year. The researchers ... an antifungal drug that has been in use for more ... toxic to human cells as it is to the microbes ... findings appears in Nature Chemical Biology . , "Invasive ...
(Date:4/15/2014)... Diego School of Medicine have identified a mechanism that ... liver disease and why the virus is able to ... The hard-to-kill pathogen, which infects an estimated 200 million ... the mitochondria dismantling the cell,s innate ability to ... dynamics. , The study, published in today,s issue of ...
Breaking Medicine News(10 mins):Health News:Celldex's Phase 1 study of CDX-1401 published in Science Translational Medicine 2Health News:Celldex's Phase 1 study of CDX-1401 published in Science Translational Medicine 3Health News:Celldex's Phase 1 study of CDX-1401 published in Science Translational Medicine 4Health News:Surveillance colonoscopy recommendations for average-risk patients with 1 to 2 small polyps consistent with guidelines 2Health News:Surveillance colonoscopy recommendations for average-risk patients with 1 to 2 small polyps consistent with guidelines 3Health News:Pre-diabetes and diabetes nearly double over the past 2 decades 2Health News:Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works 2Health News:Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works 3Health News:Breaking bad mitochondria 2
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