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UAB scientists discover the origin of a mysterious physical force

...ate cell membranes to enter cells. These drugs are often proteins designed to prevent or strengthen the action of other substances. In these cases, accurately identifying the protein folding is essential, since the form these proteins take on when they fold influences how effectively they are able to act. ...

New, automated tool successfully classifies and relates proteins in unprecedented way

...ssigned manually by database curators, and this is often notconsistent between different curators," said Murphy.Murphy and his colleagues are currently amassing more protein imagedata using CD Tagging so that they can refine their approach further.They are also working on ways to "train" a general system t...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...tablished and stable, but clearing out the plaques often led to rapidrecovery of normal structure over a few days," says senior author DavidH. Holtzman, M.D., the Charlotte and Paul Hagemann Professor and headof the Department of Neurology. "This provides confirmation of thepotential benefits of plaque-cle...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...water. The disease can cause liver damage but more often causes dysentery, a severe diarrhea that is often associated with blood in the feces. Unchecked, the diarrhea associated with the disease can be fatal...

Key molecule in plant photo-protection identified

...tablished and stable, but clearing out the plaques often led to rapidrecovery of normal structure over a few days," says senior author DavidH. Holtzman, M.D., the Charlotte and Paul Hagemann Professor and headof the Department of Neurology. "This provides confirmation of thepotential benefits of plaque-cle...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...n 20 years after diagnosis. Since the disease most often strikes older adults, the patients whose disease follows this course usually die with the disease, not because of it. CLL may also follow a more aggressive course. In these cases, patients do require chemotherapy and have a lifespan of only about six...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...rum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free. The authors of the Lancet study have reported different proteomic patterns in three separate data sets. Researchers at...

New species from old data

...rum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free. The authors of the Lancet study have reported different proteomic patterns in three separate data sets. Researchers at...

Cracking the olfactory code in bees

...rum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free. The authors of the Lancet study have reported different proteomic patterns in three separate data sets. Researchers at...

Signaling protein builds bigger, better bones in mice

...rum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free. The authors of the Lancet study have reported different proteomic patterns in three separate data sets. Researchers at...

Computers to be used to find blueprint for new influenza drug

...ery important task," said Professor Williams. “We often think of flu as just a nasty illness which puts us in bed for a few days. But some outbreaks can cause death on a large scale ?the world-wide outbreak in 1918 killed more people than the First World War itself. We may now be facing another flu outbre...

Ecological destruction fuels emerging diseases

...has found more than 5,000 different types of these often microscopic hangers-on and created one of the worl...hat will require a detailed understanding of their often complex multi-host life cycles. "It's very difficult to link these things up," he says. "It's very ...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...“In my own research onneurological diseases, we’ve often wished we could rapidly synthesizemany variations of large naturally occurring genes. The costs ofcurrent technology have prevented us from doing this, but Dr. Gao’sresearch will break down that barrier.?This technology offers tremendous potential be...

Study Links Ebola Outbreaks To Animal Carcasses

... they occurred. "The signs of potential outbreaks often occur in remote areas, where roads are barely usable and communications limited," added Karesh. "Conservation organizations such as WCS are therefore critical to the early detection of the conditions that can lead to deadly health emergencies." ...

U-M scientist to talk about tissue engineering at AAAS

...en a cancerous tumor is removed from the jaw, that often means taking a bone graft from someplace like the hip. That approach has problems both for the wound at the donor site and for the site where it is implanted. In addition to discussing the sometimes-messy real world applications of tissue engineerin...

U of M researcher examines newly emerging deadly disease

...al toxins that activate large numbers of T cells), often leading to death due to hypertension and shock. Purpura fulminans has been identified in five cases in the Minneapolis-St. Paul, Minn., metropolitan area during 2000-2004, as described in the April 1, 2005 issue of Clinical Infectious Diseases. This ...

Mitochondrial DNA mutations play significant role in prostate cancer

...sm outside ofeach cell's nucleus. The mitochondria often are called the "powerhouse"of the cell because they produce about 90 percent of the body's energy.John A. Petros, MD, associate professor of urology and pathology atEmory University School of Medicine and the Winship Cancer Institute,and Douglas C. W...

Gene therapy converts dead bone graft to new, living tissue

...e cancers, or tumors that occur adjacent to bones, often must be treated by removing the diseased section of bone and replacing it with the only alternative available ?a donated section of comparable bone from a cadaver. The new splint of bone is then literally screwed into place, giving the patient most o...

Mouse brain tumors mimic those in human genetic disorder

...ore may be promising drugtargets; and brain images often used to determine the need fortreatment may not actually be diagnostically informative. "Thesemice develop brain tumors with many of the same features as those seenin children with NF1, and studying those tumors has helped usunderstand the cellular ...

Gene variations explain drug dose required to control seizures

...(IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to fi...ctivity in the brain, was found significantly more often in patients on the highest doses of both carbamazepine and phenytoin. SCN1A has been implicated in m...

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(Date:7/11/2014)... the normal circumstances, astrocytes participate in normal ... and exhibit therapeutic and repairing effects on ... have found that nerve cells differentiated from ... reduced viability, which produces influences on subsequent ... General Hospital, Hebei United University, China demonstrated ...
Breaking Biology News(10 mins):A new genome editing method brings the possibility of gene therapies closer to reality 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
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