UCSD biologists find new evidence for one-way evolution
...l Proceedings of the National Academy of Sciences, offers new support for the idea that the loss of complex traits, like eyes, wings or in this case a reproductive mechanism, is often irreversible. In other words, once lost, the traits never revert to their original state. "This is the strongest evidence ...Ticks, flukes, and genomics: Emerging pathogens revealed
... the first time, our comparative genomics database offers a resource for tackling these questions." Recognized since at least the 1930s, ehrlichiosis sickens not only humans, but also dogs, cattle, sheep, and other animals. In Japan, human ehrlichiosis is commonly called sennetsu fever. In the U.S., most h...Mouse to man: The story of chromosomes
...ing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals, said a Baylor College of Medicine researcher who participated in this effort reported in today's issue of the journal Nature. The work represents the first time that a mouse chromo...On a fly's wing, scientists tally evolution's winners and losses
...ing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals, said a Baylor College of Medicine researcher who participated in this effort reported in today's issue of the journal Nature. The work represents the first time that a mouse chromo...Oh, rats! Designer animals reveal possible heart disease genes
... associated with the condition. "This information offers an unprecedented amount of data for cardiovascular researchers to now mine," remarks Lee, senior author of the study. Lead author Renae Malek, also a molecular biologist at TIGR, notes that the data point to promising genes for salt-sensitive hyperte...Minor mutations in avian flu virus increase chances of human infection
...gle experiment," Berg said. "The glycan microarray offers a detailed picture of viral receptor specificity that can be used to map the evolution of new human pathogenic strains, such as the H5N1 avian influenza, and could prove invaluable in the early identification of emerging viruses that could cause new ...Single microRNA causes cancer in transgenic mouse
... sufficient to cause cancer in mice. The discovery offers new insight into the development of some forms of leukemia and lymphoma and at the same time underscores the powerful role that these tiny snippets of non-coding RNA play in cell signaling pathways active in carcinogenesis. "To the best of our know...UC Riverside psychologist explores human perception, finds 'wow factor'
...e comprehend." The ambient sound in any room also offers more information than people might expect, Rosenblum said. One experiment asked subjects to listen to recorded sounds and try to recognize where on campus the recordings were made. "We picked different places -- a men's bathroom, the old gym, a walk...U of S researchers develop new vaccine candidate against hepatitis C
...in in a highly significant manner," he said. "This offers a very promising approach to prevent liver disease caused by the virus and to ultimately eliminate it from the body." About 20 per cent of people who contract HCV overcome the virus on their own. For those who develop chronic hepatitis, the immune ...Therapeutic prospects beyond Vioxx
...he mechanism involved. Clarification of this issue offers the prospect of conserving the clinical benefit of these drugs for patients with arthritis, while managing the risk. Almost 10 years ago, FitzGerald noticed that both Celebrex and Vioxx depressed in healthy individuals a protective fat called prost...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...a primary cause of skin and soft tissue infections offers implications for prevention and treatment. In the past, Dr. Blumberg says, "skin and soft tissue infections occurring in the community were generally MSSA, and that is how antibiotic therapy was targeted." Currently, many doctors may assume that co...New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice
...rkers have a higher rate of breast cancer. It also offers a promising new explanation for the epidemic rise in breast cancer incidence in industrialized countries like the United States. The National Cancer Institute and the National Institute of Environmental Health Sciences, agencies of the federal Natio...More evidence mammals, fruit flies share make-up on function of biological clocks
...t New York University and the University of London offers additional evidence that mammals and fruit flies share a common genetic makeup that determines the function of their internal biological clocks. The research team consisted of post-doctoral researcher Ben Collins, Esteban Mazzoni, a graduate student...A step forward in the fight against bacterial infections
...ogical process that underlies this natural ability offers perspectives for the development of new therapeutics. A cascade of reactions protects us against infections Most of the time, our body can overcome bacterial infections. Only a limited number of bacteria can make us sick, but sometimes they can ...Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection
...sponse that tracks to migrating glioma islands and offers long-term protection ?all of which would make this a very attractive therapeutic option." In the animal study, bone marrow-derived neural stem-like cells (BM-NSC) genetically engineered to produce IL-23 were injected into intracranial gliomas and ot...U of MN uses robotic surgery techniques in cardiac cell therapy research
..., and requires less time under anesthesia. It also offers surgeons a magnified view of the heart and allows them to target the cell infusion more precisely. Harald Ott, M.D., co-leader of this study, now a surgery resident at Massachusetts General Hospital in Boston, pointed out, "Currently these types of...Scientists elucidate the kinome of key model organism
...ctyostelium. Led by Dr. Janet Smith, this study offers important insights into the evolution of kinases, which are enzymes involved in cell communication pathways. Approximately 2.5% of human genes code for protein kinases, and mutations in many of these genes are at the root of a range of human disease...Speeding discovery of the 'human cancer genome'
...the researchers said. Their new mouse model now offers an "excellent setting" for preclinical tests of the potential of cIAP1 and Yap as targets for new cancer therapies, they added. Taken together, the papers demonstrate a general principle with real importance for cancer patients, Chin said. "Rob...Ultrasound may help regrow teeth
... have created a miniaturized system-on-a-chip that offers a non-invasive and novel way to stimulate jaw growth and dental tissue healing. "It's very exciting because we have shown the results and actually have something you can touch and feel that will impact the health of people in Canada and throughout t......timulates immune response. Chen said the finding offers the first strong evidence in favor of the 15-year-old "combinatorial control" theory of gene expression. According to the theory, the specific expression of a gene depends on the combination of "transcription factors" acting on it. Transcription fa...