Protein helps regulate the genes of embryonic stem cells
...ssue of the journal Current Biology. The research offers an important contribution to a new wave of thinking in genetics: that not all human disease states are due to alterations in DNA sequence. Dr. Terry Magnuson - Sarah Graham Kenan professor, chairman of genetics and director of the Carolina Center for...Roots Engage in Underground Chemical Warfare
...atural production of these antimicrobial chemicals offers one explanation for why so few bacteria types actually cause disease in plants. Of the more than 50,000 plant diseases occurring in the United States, fungal pathogens are the leading cause. "Current understanding of plant defenses does not readily ...NIAID begins clinical trial of West Nile virus vaccine
...xploitation of both cellular and antibody immunity offers a potentially potent defense against West Nile virus," says Barney Graham, M.D., Ph.D., chief of the VRC's Clinical Trials Core Laboratory. Adds Dr. Graham, "In our experience in clinical trials, DNA vaccines generally cause few side effects, making ...One gene links newborn neurons with those that die in diseases such as Alzheimer's
... relates to a fascinating, learned behavior, so it offers the opportunity to show how integration at different levels of biology can be made to pay," Nottebohm says. "It allows us to think about the brain in ways that no single level of analysis would allow." ...Defensins Ward Off HIV In Two Ways
...pha-defensin-1 acts on both the virus and the cell offers insights into the function of alpha-defensin-1 in innate immunity against HIV. In addition, this study provides a basis to develop defensin-like drugs for prevention of HIV and for therapeutic use in patients who are already infected. ...NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
... "It appears that p21 activation through sulindac offers protection against both a lack of tumor suppressor genes as well as poor diet," says the lead author, WanCai Yang, M.D., an assistant professor of medicine. While the drug is a NSAID (non-steroidal anti-inflammatory drug) and a COX-2 inhibitor, Yang ...Product improves peptide identification for proteomics research
...rts. The Agilent 1100 Series LC/MSD Trap XCT Ultra offers significantly improved scan cycle times, enabling collection of mass spectra at rates up to three times faster than its predecessors. "The combination of the new LC/MSD Trap XCT Ultra with Agilent's breakthrough HPLC-Chip/MS technology will set a ne...The lopsided brain: Attention bias is shared by humans and birds
...n in the two hemispheres; the new finding in birds offers some insight into how and why this might be. In the new work, researchers tested two bird species, the domestic chick and the pigeon, for their performance on a task in which they were allowed to freely peck at grains of food that were spread evenly...Stem cell research - new cell lines
... cure for it. "Human embryonic stem cell research offers a permanent answer to the problem. It gives the hope that we can produce a pure population of those cells in large numbers and transplant them into the patient." The researchers are currently in the discovery phase, where they are trying to characte...Comprehensive biodefense text published
...efense: Infectious Disease and Counterbioterrorism offers a detailed look at the ongoing efforts to detect and identify these disease-causing agents, including proteomic and genomic analysis as a gateway to better diagnostics, therapeutics, vaccinations, genotyping, and forensics. ...TrueBlue Archive Will Store Raw Life Sciences Data for Proteomics and Drug Testing
...efense: Infectious Disease and Counterbioterrorism offers a detailed look at the ongoing efforts to detect and identify these disease-causing agents, including proteomic and genomic analysis as a gateway to better diagnostics, therapeutics, vaccinations, genotyping, and forensics. ...Whole-body MRI Takes Less Than 20 Min To Scan A Patient's Entire Body For Cancer Spread To Bone
...es an automatic moving table and fast software. It offers a better sensitivity and higher specificity in detecting bone metastasis than other methods,?said Joan C. Vilanova, MD, lead researcher for the study. In addition to all its benefits, say the researchers, whole-body MRI is not just limited to findin...Penn Researchers Use Robotic Surgery
... therapy, and chemotherapy. In many cases, surgery offers the greatest chance of cure. Conventional cancer surgery can consist of an almost ear-to-ear incision across the throat or splitting the jaw in half. This can result in speech and swallowing deficits for patients. "The research we've done to date sug...Two new retroviruses—transmitted from animals—identified
... therapy, and chemotherapy. In many cases, surgery offers the greatest chance of cure. Conventional cancer surgery can consist of an almost ear-to-ear incision across the throat or splitting the jaw in half. This can result in speech and swallowing deficits for patients. "The research we've done to date sug...Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
...s her own mutants. Creating the mutants on her own offers two advantages. First, instead of making mutants with chemicals and radiation, her group uses transposons--small DNA segments that can replicate on their own and insert their copies into new positions anywhere in the genome. Mutations induced by tran...DOE JGI launches IMG public online microbial genome data clearinghouse
...me sequence with DOE JGI sequences, the IMG system offers a powerful data management platform that supports ...abolic reconstructions. "The first release of IMG offers a comprehensive genome data exploration system of the DOE JGI-sequenced genomes to our collaborators......asonic Transmission Tomography" (HUTT) system that offers 3D images of soft tissue that are superior to thos..., held March 20-23. According to Marmarelis, HUTT offers nearly order-of-magnitude improvement in resolution of structures in soft tissue (i.e., 0.4 mm, comp...Scientists use manufacturing methods to reconstruct mastodon
... museum director Amy Harris. "The expanded exhibit offers us an opportunity to feature his research in interesting and engaging ways." In addition to being an impressive addition to the museum's exhibit space, the Buesching mastodon is important for what it can contribute to scientific understanding, Fishe...New vaccine means bye-bye to bacteria in the lung
...inst Pseudomonas aeruginosa is therapeutic in mice offers promise for patients with cystic fibrosis or other disorders that prevent them from effectively fighting off respiratory tract infections. ...Study of energy and health in Africa focuses spotlight on charcoal and forest management
...life in one of the world's most impoverished areas offers us opportunity to significantly reduce premature deaths, especially among women and children," said Ezzati. ...