An artificial cornea is in sight, thanks to biomimetic hydrogels
...ls grow over the top of the inlayed lens. Inlays offer an advantage over LASIK surgery, which works but isn't reversible, Myung says. He envisions implantable contact lenses that can be replaced if the prescription changes. Hydrogel lenses may even make their way deeper into the eye as replacements for...Report calls for improved monoclonal antibodies against solid tumors
...rgeting strategy.?They conclude the framework they offer “should facilitate critical choices among antibody constructs in clinical practice, clinical research, and preclinical research.?...Few clues about African ancestry to be found in mitochondrial DNA
...ace maternal ancestries, and several companies now offer to analyse individuals' mitochondrial DNA sequences to obtain information about their origins. The current study suggests that only one in nine African Americans may be able to find clues about where their ancestors came from, in their mitochondrial ...High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping
...d the Broad Institute of Harvard and MIT, may also offer aid in the testing and development of tailored treatments, according to researcher Levi A. Garraway, M.D., Ph.D., an assistant professor in the Dana-Farber Department of Medical Oncology. "It may help clinical testing of new targeted therapies, becau...Squid-inspired design could mean better handling of underwater vehicles
...ortex thrusters designed by CU-Boulder researchers offer speed with versatility and may enable researchers to explore previously inaccessible places. Currently, many designers are trying to devise better docking systems for underwater vehicles, but Mohseni said he and his collaborators wanted to improve t...Hope for major advance in fighting world killer disease
...now being piloted in four hospitals in India, will offer a means of identifying the two most deadly forms of the disease quickly, cheaply and with little training necessary for practitioners. The implications for improving children's health could be enormous. Diarrhoea is a major killer in developing co...Worms produce surprise insight into human fever
...ce fever but also activate HSF-1 signaling, could offer the best of both worlds, says Aballay. He also points out that new drugs designed to activate HSF-1 are already in clinical trials for treating neurodegenerative diseases. “Our work opens the possibility of using co-inducers of HSF-1 to boost immu...Human stem cells delay start of Lou Gehrig's disease in rats
...ly died of ALS, Koliatsos believes his experiments offer "proof of principle" for stem cell grafts and that a more complete transplant of cells - already being planned -- along the full length of the spine to affect upper body nerves and muscles as well might lead to longer survival in the same rats. ...Flu shot effective against drifted influenza, nasal spray vaccine less so
...e nasal spray, sold by MedImmune as FluMist, might offer better protection against drifted viruses that had...em this year, to see whether the shot or the spray offer long-term protection. ...MIT designs portable 'lab on a chip'
...ches to designing labs on a chip, neither of which offer portability. The first is to mechanically force fluid through microchannels, but this requires bulky external plumbing and scales poorly with miniaturization. The second approach is capillary electro-osmosis, where flow is driven by an electric fi...Uniform tungsten trimers stand and deliver
...and Washington State University, the discovery may offer a platform for fundamental reactivity studies of metal oxides used as catalysts in converting hydrocarbons into fuels and value-added chemicals. "There is a striking difference between commercial catalysts and the new model system," said Mike White,...Pair of microRNA molecules controls major oncogene in most common leukemia
...f gene expression in cancer development, and could offer new targets for drug treatment, the investigators say. In this case, high levels of two miRNAs known as miR-29 and miR-181 seem to suppress expression of the TCL1 oncogene that drives the most aggressive forms of the leukemia, said the study’s le...Biofuel cells without the bio cells
...powerful enough to be commercially viable but they offer the promise of breaking down sewage and other biological waste while generating electricity directly from the same process. An example, Squier said, is a self-powering sewage treatment plant. Using pure protein opens up the possibility of shrinking...Cardiologist's 'living chip' changes science of disease monitoring
...ork with High Tech Rochester and other entities to offer their advice in the areas of business-plan writing, marketing surveys, legal counsel and anything else an entrepreneur needs to develop a successful business. By using these Rochester experts, the researcher doesn't have to spend time learning those ...Therapeutic role found for carbon monoxide
... treat and reverse existing disease. "Our results offer the exciting possibility that in extremely low concentrations and for brief intermittent exposures of one hour per day, CO gas might be effectively used as a therapy to treat PAH in a clinical setting," says Otterbein, an investigator in the Transpla...Study: Living coral reefs provide better protection from tsunami waves
...example. The model demonstrates that healthy reefs offer the coast at least twice as much protection as dea...direct human damage, Oppenheimer said the findings offer yet another reason to protect these fragile offshore ecosystems. "This study shows yet another wa...Three-dimensional, miniature endoscope opens new diagnostic possibilities
...miniature endoscopes." "This new technology will offer physicians and surgeons the capability to bring many more procedures into outpatient settings, reduce anesthesia requirements and minimize tissue damage," Tearney adds. "The device's size and flexibility should allow safer navigation through such del...Pilot study successful in taming allergic reactions to food
...n that it brings us a step closer to being able to offer a meaningful therapy for these people.? Egg alle...niversity of Arkansas. The goal, Burks said, is to offer food allergy sufferers protection from accidental ingestion of items that provoke reactions and, eve...Parkinson's mutation stunts neurons
...ment. The researchers wrote that their findings offer "a useful animal model for early LRRK2-associated disease." They concluded that their techniques of introducing the mutated gene could lead to a primate model for the form of PD. "These cellular and animal models may promote the discovery of effectiv......re thought to have separate ancestors, the studies offer a new understanding of the development of the mammalian heart ?the earliest organ to develop, and the one most susceptible to congenital defects. They also bring researchers a step closer to being able to regenerate tissues to repair congenital heart...