New insight into machinery of immune cells' 'tentacles'
...inery of formation of such "actin filaments" could offer targets for drugs to induce the immune system to work more effectively to fight infection; or to damp its stimulation in autoimmune disease. Led by Duke University Medical Center pharmacologist Ann Marie Pendergast, the researchers published their f...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...inhibitors to bind to the active site, or it could offer a new way of inhibiting protease activity from afar by itself, Perryman suggested. Now that he can prevent the simulated flaps from opening by using an artificial force, Perryman and co-author Jung-Hsin Lin of National Taiwan University hope to di...Computer simulation hints at new HIV drug target
...inhibitors to bind to the active site, or it could offer a new way of inhibiting protease activity from afar by itself, Perryman suggested. Now that he can prevent the simulated flaps from opening by using an artificial force, Perryman and co-author Jung-Hsin Lin of National Taiwan University hope to di...Therapeutic prospects beyond Vioxx
... problems, in multiple animal models. The findings offer the prospect of a new generation of anti-inflammatory drugs that bypass this issue, as reported in the April 13 advanced online edition and May print issue of The Journal of Clinical Investigation. "Although these results are in mice, not people, th...How can we protect patients with weakened immune systems from influenza?
...ns and supplies of vaccine are limited. We want to offer protection to these special populations of immunocompromised patients, but not to vaccinate them needlessly." Patients on chemotherapy, on immunosuppressive drugs, or with diseases that weaken the immune system may be especially vulnerable to influe...Potential heart benefit found in stem cells
... treatment with bone-marrow derived stem cells may offer an effective alternative to improving cardiac function," said Helmut Glogar, M.D., of the Medical University of Vienna, and lead author of the study. ...FSU biologist says new dinosaur is oldest cousin of Tyrannosaurus rex
...ago. The new, nearly complete skeletons from China offer a snapshot of the earliest tyrannosauroid just after they morphed into a different branch of the family tree –?95 million years before cousin T. rex ruled the roost. Researchers say the identification of the oldest basal (primitive) tyrannosauroid y...Georgia Tech accelerates drug discovery with new IBM supercomputing cluster
...uters. The system performance and scalability will offer students and faculty the ability to quickly and accurately analyze complex DNA and proteins to determine the biological and chemical processes of human cancer genes and proteins, to aid in the development of more targeted drugs to treat such diseases...Anti-HIV drug has potential to prevent transmission in women
...e sexual transmission of HIV. Although condoms can offer protection from HIV, in many societies women's leg... "A safe and effective topical microbicide would offer women an HIV prevention method that they could control," Mayer says. In addition, researchers eval...New brain hormone puts brakes on reproduction
... is mirrored in humans and other mammals, it would offer physicians another means of tweaking the reproductive system to fix problems ranging from infertility to precocious puberty, and also provide animal breeders with a new way to manipulate the productivity of livestock. The findings by Kriegsfeld and ...Movement of chromosome in nucleus visualized
...llinois' Chicago and Urbana-Champaign campuses now offer the first imaging evidence from live cells of ongo...tors. de Lanerolle and his colleagues were able to offer the Belmont laboratory a number of ways to test whether the chromosome movement was actin/myosin-dep...UF researchers develop ways to keep the bloom on the rose
...e satisfaction and enjoyment. "It's not enough to offer consumers a beautiful flower," Nell said. "It needs to come with an extended warranty to remain lovely for a reasonable period of time. Our research is providing scientific basis for that kind of guarantee." ...Thin tough skin, slow-growing gills protect larval Antarctic fish
.... The delicately thin skin of the larval fish may offer additional protection, because their skin hasn't yet been exposed to environmental damages, Cheng said. The skin and undeveloped gills, Cziko said, may combine to allow time for antifreeze levels to rise. The production of AFPs did not show much inc...Earth Rx: A microbial biotechnology prescription for global environmental health
...y and environmental biotechnology. "Together, they offer much promise for helping society deal with some of its greatest challenges in environmental quality, sustainability, security, and human health," Rittmann stated in an excerpt from the paper. For the majority of Earth's 6 billion year history, micro...Botox could help target resistant tumors for treatment
...ensitizes the tumor to treatment. Botox appears to offer the advantage of selectivity, absence of toxicity and persistence for a longer time than other agents that act on tumor vasculature. Further research may help us determine whether this approach would be useful to treating cancer in humans." The Gall...How 'hot' emotional brain interferes with 'cool' processing
...evant to a task. Moreover, they said, the findings offer a new approach to understanding how people with depression and post-traumatic stress disorder cope with traumatic events and memories. It is known that people with such problems are far more affected by emotional distraction. Development of new dru...UCI researchers discover key factor for survival of human embryonic stem cells
Human embryonic stem cells (hES) offer great hope for the treatment of some devastating d...the body. According to Donovan, the studies also offer further proof that new stem cell lines need to develop beyond those already in existence. Federally ...Heart-healthy compound in chocolate identified
...avanol-rich foods, such as wine, tea and cocoa can offer cardiovascular health benefits, we have been able to demonstrate a direct relationship between the intake of certain flavanols present in cocoa, their absorption into the circulation and their effects on cardiovascular function in humans," said UC Da...Unique equine cataract surgery offered on routine basis
...roblem. We are pleased that the University can now offer such progressive treatment to tackle equine cataracts on a larger scale than currently available." The surgery has successfully been carried out on several horses at the University, including TC, a nine-year old Gelding warmblood, who had develope......"learn" a craving for cocaine. Their finding could offer an important target for drugs to treat addiction by short-circuiting that adaptive process. In an article in the February 16, 2006, issue of Neuron, Antonello Bonci and colleagues established that a short protein, or peptide, called orexin A acts on...