Mutation in blood stem cells provides clues to cancer development
A mutation in blood stem cells occurs in patients with a blood disorder called polycythemia vera (PV), scientists at the Moores Cancer Center at the University of California, San Diego (UCSD) and the Institute for Stem Cell Biology and Regenerative Medicine and Comprehensive Cancer Cente...A case of mistaken molecular identity
...e cause of the misguided attack. Molecular mimicry occurs when a molecule that is part of an infectious agent resembles a molecule native to the body. Eventually, the immune system begins to mistake the native molecule for the invader. Levin's investigations revealed that an intra-cellular T. cruzi protei...Weighting cancer drugs to make them hit tumors harder
...ree-dimensional penetration and accumulation as it occurs -- information that is critical to achieving optimal results," said Matthew Dreher, a graduate student in biomedical engineering and lead author of the study. "We quantified tumor blood vessel permeability and we examined precisely where in the tumor...Even fish don't swim well when they're young!
...age. In marine fish more than 99% of the mortality occurs in the larval stage so anything that might explain what holds them back is useful". Müller will present her research on Monday 3rd April, at the Society for Experimental Biology's Annual Main Meeting in Canterbury [session A5]. The 'burst-and-coast'...Taking evolution's temperature: Researchers pinpoint the energy it takes to make a species
...als or plants actually evolve into a new species - occurs when life forms with a common ancestor undergo substantial genetic change. Using a mathematical model based on the body size and temperature-dependence of individual metabolism, the researchers made specific predictions on rates of speciation at the...Scientists uncover rules for gene amplification
...event will result in a double minute. If the break occurs between the oncogene and the telomere, then the amplification would yield a homogenously-staining region." adds Vidhya Narayanan a Ph.D. student in Kirill Lobachev's lab and first author of the study. The findings can help researchers understand the...New human retrovirus originated in mice
...us at best. "First, the genetic variant we studied occurs in familial clusters that constitute only a very small sliver of prostate cancers," he said. "And secondly, there are many reasons to believe that the virus might not relate to prostate cancer." For example, he pointed out, analysis of prostate tis...Scientists find Antarctic ozone hole to recover later than expected
...tarctic ozone hole is a massive loss of ozone that occurs each spring in the Southern Hemisphere. The ozone hole is caused by chlorine and bromine gases in the stratosphere, an upper layer of the atmosphere, that destroy ozone in an annually recurring process that takes place in the unique meteorological co...Attacking cancer's sweet tooth is effective strategy against tumors
...that cancer cells change over to glycolysis, which occurs in the cytoplasm, because the mitochondria, where oxygen-dependent ATP synthesis occurs, are defective. But the mitochondria of cancer cells appear to be mostly intact, which led many researchers to minimize the importance of the glycolytic switch. ...First human trial of antibacterial contact lens
...coming this significant problem." Acute red eye occurs in 20 per cent per year of the estimated 100 milli...is, a serous eye disease that can cause blindness, occurs in one in 500 contact lens wearers per year if they sleep in lenses. There is currently no antibacte...NASA study solves ocean plant mystery
...based measurements of fluorescence. Fluorescence occurs when plants absorb sunlight and some of that energ... Approximately half of the photosynthesis on Earth occurs in the oceans, and the remainder on land. Ocean and land plants share the same basic requirements fo...Scientist-astronaut sends T-cells into space
..., he'll be simulating the activation that normally occurs in response to infection," Hughes-Fulford explains. "He'll be setting up the whole cascade that would normally turn on the T-cells. Except we know that some of the genes will not turn on because they're in a weightless environment." At the end of t...It's not fair! We are programmed to resist weight loss
...t these studies show that a plateau in body weight occurs even in the face of a continued negative energy balance." In the first study, 30 obese men and women took part in a 12-week, laboratory-based exercise program in which they exercised five times a week. The second study looked at weight loss in 20...Atmospheric ozone recovering in mid-latitudes, report shows
... cycle, and another is a two-year oscillation that occurs in the tropics, but affects ozone in other latitudes because of atmospheric transport. Despite the natural fluctuations, Yang, Cunnold and their co-authors are very confident in the conclusions they reached from the data they analyzed. "We know from......um honey'. Leptospermum is a species of tree which occurs in New Zealand and Australia. Honey from these trees has a particularly strong anti-bacterial effect, even in a 10% dilution. 'It is not yet known exactly why this is,' Dr. Arne Simon says. 'Probably it is a mix of phenol-type substances which come f...Revolution in the fight against cancer & viruses
... describe how they have manipulated a process that occurs naturally throughout the human body, into a potential therapeutic tool. "The process, called RNA interference, blocks the production of proteins that create cancer and viruses," said research leader and Director of the Monash Institute of Medical Re...Creating a window on 'oceans in motion'
...bout 80 km (50 mi) wide, and the edge of the shelf occurs at an average depth of about 200 m (660 ft), where it falls steeply into the deep sea. Salmon and many other marine animals travel extensively along shelves. A pilot array has been successfully demonstrated by the British Columbia-based Project POS...Production of key Alzheimer's protein monitored for first time in humans
...r's prior to the onset of clinical symptoms, which occurs after Alzheimer's has inflicted widespread and largely irreversible damage to the brain. "We hope to study whether we can develop ways to identify potential Alzheimer's patients on the basis of a metabolic imbalance between Abeta synthesis and clea...Many cleaners, air fresheners may pose health risks when used indoors
...l ethers; and an examination of the chemistry that occurs when such products are used indoors ?in particular, products that contain a reactive group of chemicals called terpenes. Ethylene-based glycol ethers are common, water-soluble solvents used in a variety of cleaning agents, latex paints and other pro...Viagra improves high altitude exercise performance up to 45% for some
...onstriction of vessels in the lungs that sometimes occurs at altitude. In turn, that would allow greater blood flow through the heart, better transfer of oxygen from the lungs to the blood and improved oxygen delivery to working muscles. The participants, all trained cyclists, performed a total of 10 cycli...