Research updates 65-year-old genetic discovery
...niversity of Utah. "No chimpanzees were harmed to obtain the samples," Stone notes. The DNA is provided by veterinarians and comes from either blood samples or cheek swabs. She uses these samples to help zoos, sanctuaries and primate centers identify subspecies of chimpanzees. "My goal is to better unders...Some like it hot: Worms at deep-sea vents favor a fiery 45-55°C
...l survive brief forays into similarly hot areas to obtain food, but do not choose to remain in superheated environs as Alvinellids do. "We speculate that these worms have evolved to prefer and tolerate these temperatures because it allows them to graze on bacterial lawns that no other organism can access,"...Novel method reveals how menthol discovery could point towards new or improved pain therapies
... channel protein that would have been difficult to obtain using other mutagenesis methods." Because the methodology can be used to screen for activation or inhibition, Bandell added, it could prove to be useful as a general method to analyze the mechanism by which drugs can activate or inhibit ion channe...High-resolution light microscope reveals the fundamental mechanisms of nerve communication
...tion (STED) microscopy.The STED microscope used to obtain data for both publications is able to attain a resolution of 50-70 nm; the original fluorescent spot, roughly 200 nm in diameter, is reduced in surface area within the imaging plane by roughly an order of magnitude using the STED technique. This res...Potential heart benefit found in stem cells
...e team collected menstrual blood from six women to obtain a sample of endometrial cells (E-DOM). The researchers found that approximately half of the E-DOM cells contracted simultaneously, suggesting an electrical communication between the cells. Further analyses of the cells revealed appropriate cardiac g...Lizard 'third eye' sheds light on evolution of color vision
...third eye. Yau hopes to pursue these structures to obtain more clues about how our photoreceptor cells, the rods and cones, came about. As he says, he's most curious about how the same function can be achieved in different ways in different animals. ...Molecule by molecule, new assay shows real-time gene activity
...oduction. "Dr. Xie's experiments are the first to obtain quantitative, real-time information on protein expression in living cells at the single-molecule level," says Jeremy M. Berg, director of the National Institute of General Medical Sciences, which funded the work in part. "His imaging methods open up ...Why nerve cells work faster than the theory allows
...acteristics behave like both sides of a seesaw. To obtain a high variability of the threshold value, the model requires a low speed of initiation of the action potential. A rapid onset is only obtained, when the variability of the threshold value is low. In order to recreate the observed behavior of the n...International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy
...nvestigators around the world can work together to obtain an answer to an important HIV treatment question." Further information concerning the study findings can be found in a Questions and Answers document below. An earlier NIAID news release describing the initiation of the SMART trial can be viewed at ...Mayo Clinic collaboration discovers protein amplifies DNA injury signals
...grants from the National Institutes of Health. To obtain the latest news releases from Mayo Clinic, go to www.mayoclinic.org/news . MayoClinic.com ( www.mayoclinic.com ) is available as a resource for your health stories. ...GlycoFi announces the first production of antibodies with human glycosylation in yeast
...f glyco-engineered yeast cell lines and expects to obtain a large array of specific glycoprotein variants that were hitherto unobtainable at a commercial scale. The company believes that as the scale-up and recombinant production of proteins in yeast is a well established technology, more easily achieved th...High-tech tags on marine animals yield valuable data for biologists and oceanographers
...esearchers can use these Antarctic seal species to obtain oceanographic data for a region of the ocean and times of the year for which there are no good sources of data, Costa said. This is particularly important because of the major role played by the Southern Ocean in the global climate system. "Much of...Fruit fly's beating heart helps identify human heart disease genes
...measure the thickness of the retina in the eye, to obtain detailed images of the beating heart of an adult, unanesthetized fly. "After inserting into the fly the gene that we know is implicated in dilated cardiomyopathy in humans, we imaged the adult fly with this novel system and what we saw looked exactl...Intelligently designed molecular evolution
...parts of a molecular compound, and combine them to obtain a final product that could do whatever you needed it to do." Since plasticity residues also play other important biological roles, in addition to the evolution of promiscuous proteins, Keasling and Yoshikuni said their technology, with some modifica...Picking particles faster than one at a time
...structures which may be difficult or impossible to obtain otherwise. Instead of trying to coax molecules to arrange themselves in a repeating crystalline structure, as is necessary for x-ray crystallography, cryo-EM uses individual molecules frozen in random orientations. Capturing two-dimensional images ...Scientists crack code for motor neuron wiring
...cles. "Once we had these reagents, we were able to obtain the high resolution maps of Hox expression that were necessary to address more complex aspects of Hox function in motor neuron diversification," said Jessell. To give an idea of the extent of complexity, Jessell explained, "there are few motor colum...New technique helps researchers determine amino-acid charge
... the University of Illinois at Urbana-Champaign to obtain a detailed picture of the effect of the protein microenvironment on the affinity of ionizable amino-acid residues for protons. The findings, reported in the Dec. 15 issue of Nature, are expected to be welcome news for chemists and biophysicists, bot......ght think it would be difficult for a terrorist to obtain genes from the smallpox virus, or a similarly vicious pathogen. Well, it's not. Armed with a fake email address, a would-be bioterrorist could probably order the building blocks of a deadly biological weapon online, and receive them by post within we...Olfactory system detects pheromones that control reproduction
...he researchers could use the pseudorabies virus to obtain a detailed look at all of the neurons that were connected to each other. "Our conditional tracing studies showed a major projection to LHRH neurons from the main olfactory epithelium and the structures that comprise the primary olfactory complex," s...