Cheaper, better disease treatments expected from faster approach to developing antibodies
...o treat human diseases that may not be possible to obtain otherwise." The results were published online Sunday, April 15, in Nature Biotechnology. Bacteria are easy to grow in an inexpensive broth. As a result, harmless forms of the bacterium E. coli have already been used as factories to produce ant...Lab research may one day lead to cancer treatment using patient's own immune cells
...searchers learn how to most effectively select and obtain the T cells for this form of therapy. In future use with humans, the cells would be grown in the cell processing facility located in the Iris S. and Bert L. Wolstein Research Building, which opened in 2003. The activated T cells would be reinfused ...Using dental X-rays to detect osteoporosis
...with an average age of 55 years were recruited. To obtain the “gold standard? the team measured bone thickness at the femur, hip, and spine, using the technique that is common for this kind of expensive examination (Bone Mass Density, BMD). In addition, one panoramic and two intra-oral radiographs were made...Chimpanzees found to use tools to hunt mammalian prey
...them with jabbing motions in an apparent effort to obtain lesser bushbabies (Galago senegalensis) from cavit...chimpanzees using the spear-like tools to find and obtain prey, the researchers observed that tool-crafting and associated hunting behavior was systematic and...Microfossils unravel climate history of tropical Africa
... The new proxy was used in this sediment core to obtain both a continental and a sea surface temperature record. A comparison of both records shows that ocean surface and land temperatures behaved differently during the past 25,000 years. During the last ice age, temperatures over tropical Africa were 21°...Novel computed imaging technique uses blurry images to enhance view
...trum light source and a spectral interferometer to obtain high-resolution, reconstructed images from the optical signals based on an understanding of the physics of light-scattering within the sample. "ISAM has the potential to broadly impact real-time, three-dimensional microscopy and analysis in the fie...Linheng Li Lab documents the development of cancer stem cells
...s to further characterize cancer stem cells and to obtain their molecular signature -- providing important insight into targeting these cells," said Robb Krumlauf, Ph.D., Scientific Director. "This is a fascinating new area of cancer research, and Linheng Li and his colleagues will continue to make importan...Scientists reveal structure of gateways to gene control
...ut the underlying architecture is the same." To obtain their high-resolution map, the researchers first isolated 322,000 nucleosomes from the 6,000 regions that control gene transcription in the DNA of baker's yeast, S.cerevisiae, an organism widely studied as a model of how human cells work. These prom...HIV dementia alarmingly high in Africa
... from the AIDs Information Center who were used to obtain normative data for the cognitive tests. In diagnosing HIV dementia, researchers looked at medical history and the results of a series of comprehensive neurological and neuropsychological tests and functional assessments. "Clearly, large-scale t...Global map shows new patterns of extinction risk
...s divided the planet up into small grid squares to obtain a really detailed picture of biodiversity. By looking at the numbers of endangered mammals, birds and amphibians in these squares, we have been able to see how this real picture varies from assumptions that have previously been made about global biod...Penn researcher shows that DNA gets kinky easily at the nanoscale
... called high-resolution atomic force microscopy to obtain a direct measurement of the energy it would take to bend lengths of DNA just a few nanometers long. The technique involves dragging an extremely sharp tip across the contours of the molecule in order to create a picture of its structure. With this...One-of-a-kind imaging probe reveals secrets useful for drug discovery
... make medicines. It also shows that scientists can obtain volumes of information from very tiny samples, whi... the component that is inserted into the magnet to obtain chemical information from the samples. Developed by scientists at the National High Magnetic Field ...German researchers develop first non-invasive test to measure skin aging
...collagen/elastin factor. The team was also able to obtain images of tiny swaths -- one-fifth of a millimeter wide -- of the proteins' fibrous matrices, showing the physical appearance of the dermis, the white lower-layer of skin that gets exposed in deep abrasions. Large variations appeared from patient ...Male contraception: One door opens, another closes
... the University of Washington, Seattle was able to obtain funding to test the drug's effect in seven healthy men. The result? Nothing--no effect on fertility, even at a dose high enough to cause diarrhea, stomach upset, and other unpleasant side effects. "We knew it was going to be either a strike out o...Molecular 'marker' on stem cells aids research, perhaps therapies
...iological marker will boost researchers?ability to obtain a purer, more homogeneous population of MSCs. That’s an important consideration, for example, in applications such as tissue engineering, where only bone-generating cells are needed. Such cells are being tested by a number of researchers for their ab...Sequencing of the oyster mushroom genome
...n, animal, vegetable and microbian), enables us to obtain an overall and more enriched picture of the evolution of life on Earth. In the second year of the project, the reading of the genome will be completed and the annotation of the genes perfected. In the end, all the information will be placed at th...New technique boosts size of proteins that can be analyzed
...d, heated and then bashed with gas molecules -- to obtain their pieces for the mass analysis. They are sprayed in an electric field where they pick up charges and are vaporized as they pass through a heated capillary. Then they are hit by air molecules in low-energy collisions to keep the protein from foldi...New technology to speed up research into Huntington's disease
...ses and were able to learn the correct stimulus to obtain a reward by day 10. The researchers also demons... they were able physically to touch the screen and obtain rewards, even though their responses were often incorrect). This indicates that their poor cognitive...From hot springs to rice farms, scientists reveal new insights into the secret lives of archaea
...ed by other microbes. Animals and people, in turn, obtain nitrogen by eating plants and other herbivorous animals. That was the dogma taught for decades in biology classes-until September 2005, when David Stahl of the University of Washington showed that bacteria do not have a monopoly on nitrification. ...Rising ocean temperatures, pollution have oysters in hot water
...emperatures and a common heavy metal are unable to obtain sufficient oxygen and convert it to cellular energ...han the unexposed group, but were either unable to obtain enough oxygen, convert the oxygen they obtained to energy, or both. The researchers drew this conclu...