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Tag: "obese" at biology news

Hormone helps mice 'hibernate,' survive starvation

...hown to lower blood glucose levels in diabetic and obese mice. FGF21, in turn, stimulates the use of stored fats as energy and causes torpor. In properly fed mice, FGF21 is not normally active; however, when the researchers introduced FGF21 into these mice, the animals’ metabolism changed. “When mice...

How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of 'fullness'

...e up with a practical weight loss solution for the obese person without his having to feel hungry. For this development, Yaniv Linde, a 32-year-old Ph.D. student of Prof. Chaim Gilon in the Department of Organic Chemistry at the Hebrew University, has been named a first place winner of a Kaye Innovatio...

In mice, drug protects against diabetes and atherosclerosis

...unity takes place even if the animals are severely obese or have high amounts of cholesterol and consume dangerously fatty foods. Use of the compound not only appears to prevent the development of these diseases, but also to reverse the symptoms of these illnesses in mice. "To have this chemical in hand...

Fat fish put obesity on the hook

... increased from 5.0% to 17.4%. Being overweight or obese increases the risk of many diseases and health conditions, including, but not limited to: hypertension, dyslipidemia, type 2 diabetes, coronary heart disease, stroke, gallbladder disease, osteoarthritis, sleep apnea and respiratory problems, and some...

BMI not accurate indicator of body fat

...ople. "Is a BMI of 25 for overweight and 30 for obese the right ones to use with 20- to 29-year-olds in terms of disease risk?" he asked. "Maybe it could be as simple as this: If you're a regular exerciser or an athlete, maybe 28 is overweight for you and 33 is considered obese." BMI, said Pivarnik, ...

In obesity, brain becomes 'unaware' of fat

Critical portions of the brain in those who are obese don’t really know they are overweight, researchers...bolism, published by Cell Press. These findings in obese mice show that a sensor in the brain that normally detects a critical fat hormone—causing a cascade ...

New player in commitment to life as a fat cell

...ributing factor to other symptoms commonly seen in obese individuals, including high blood levels of uric a... compared to their normal littermates. Genetically obese mice exhibited increased XOR activity and urate in the adipose tissue. Urate is a salt derived from ...

20-year study shows significant rise in childhood obesity, especially among girls

...ng girls were much more likely to be overweight or obese than boys. For example, in 2002 the average ten...ents have a tendency to under-report the weight of obese children and are less likely to take part in studies. "Despite high levels of parental education ...

Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight

...p in the research will be to determine whether the obese phenotype observed in the EP3 receptor deficient mice is dependent on the lack of EP3 in the central nervous system and/or peripheral organs, as EP3 is expressed in both locations. The research has interesting implications for scientists' underst...

Major link in brain-obesity puzzle found

...hat were treated to make extra SH2B1 didn’t become obese or lose their ability to respond to leptin signals even after being fed a high-fat diet that caused those effects in other mice. “Obesity, whether in mice or humans, is the product of an altered balance between energy intake and energy use. The i...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...used a single compound to increase the lifespan of obese mice, and found that the drug reversed nearly all ... mice). "The "healthspan" benefits we saw in the obese mice treated with resveratrol, such as increased insulin sensitivity, decreased glucose levels, heal...

Eating protein boosts hormone that staves off hunger

...e food intake by a third in both normal-weight and obese people when given by injection. "We've now found...emained elusive. In a study in normal-weight and obese people, the researchers now show that enhanced-protein meals stimulate greater release of PYY than e...

Dragonfly's metabolic disease provides clues about human obesity

..."What we're finding in insects is that they become obese when parasites cause inflammation that affects metabolism," said Marden. "That seems akin to what's happening in humans when they get type-2 diabetes. It's not because there's been a change in the genetic composition of the population. it's because...

For super-obese patients, duodenal switch beats gastric bypass

...tric procedure that can be applied to all severely obese patients, we have generally recommended the duoden...possibly the duration of weight loss." The super obese make up only a fraction of the U.S. obesity pandemic, but their ranks are increasing faster than any...

Higher levels of obesity associated with greater health risks

The health risks for women who are extremely obese may be underestimated as a new study indicates the...r plateaus as body weight increases throughout the obese range. Kathleen McTigue, M.D., M.S., M.P.H., of the University of Pittsburgh, and colleagues conduc...

Gut microbes' partnership helps body extract energy from food, store it as fat

... M. smithii in the gut microbial community vary in obese versus lean individuals." Gordon says the results emphasize the need to consider the nutrient value of the foods we consume in the context of the digestive capacity of our individual gut microbial communities. To help address such questions, Gordon ...

Diabetes hits 275 Australians each day as pandemic spreads

...000 people progress from being overweight to being obese (nearly 600 people daily) 400,000 adults develop hypertension, and 270,000 adults develop chronic kidney disease. The Australia-wide study was conducted by the International Diabetes Institute over the last 15 months and is the first to have meas...

Some people would give life or limb not to be fat

...eight, 21 percent were overweight, 21 percent were obese and 14 percent were extremely obese. Implicit att...tive attitudes than heavier people. Obese and very obese people exhibited only an implicit anti-fat bias, not an explicit one. "The fact that even obese ind...

Sleep deprivation doubles risks of obesity in both children and adults

... with an almost a two-fold increased risk of being obese for both children and adults. Early results of a...ference over time and a greater chance of becoming obese over time. Professor Cappuccio says: "The 'epidemic' of obesity is paralleled by a 'silent epide...

Chewing up a key regulator of fat synthesis keeps mice lean despite a high-fat diet

...ted from fatty liver disease, a serious problem in obese individuals with insulin resistance," says Montminy. Our body's ability to store fat requires the activity of the enzyme acetyl-coenzyme A carboxylase, or ACC. When we fast, the body starts to burn fat while simultaneously shutting down ACC through ...

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