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Tag: "nutritional" at biology news

Attacks of King George III's madness linked to key metabolism molecule

...bohydrate food. A biological explanation for these nutritional effects has been lacking. The Dana-Farber scienti... the cover of the August 26 issue of Cell that the nutritional component of porphyria involves a key master metabolic molecule, PGC-1 alpha, in cells of the liver....

Excess liver gene protects against high-fat diet

...etic alteration with opposite effects in different nutritional environments." The researchers examined lipid metabolism and atherosclerosis in mice with an approximately 3-fold increase in the concentration of LXRa receptors in their livers. The mice also lacked a second gene that made them particularly prone t...

NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses

... illustrate the interplay between genes and common nutritional and medicinal agents in development of cancer in the intestines. The drug they tested, sulindac, was a highly effective chemoprevention agent, the researchers say, because it worked to induce expression of the p21 gene, which they found put a firm s...

UNC launches study of liver injury caused by drugs

... by prescription and over-the-counter medications, nutritional supplements, alternative medicines and herbals. Funded by the National Institute of Diabetes and Digestive and Kidney Diseases, DILIN will be the first large-scale investigation of severe liver injury associated with drugs. Other DILIN centers alon...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

... Iron deficiency is the most prevalent and severe nutritional disorderworld wide, affecting more than 2 billion people. The most widelyrecognized symptom is anemia, in which too few red blood cells areproduced, and the body is deprived of oxygen needed for energymetabolism. Iron deficiency causes wide-ranging s...

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