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Tag: "numbers" at biology news

Man and mouse share genome structures

...n structure of the two shortest human chromosomes, numbers 21 and 22, containing about two percent of the human genome. They also sampled additional regions in both the human and mouse genomes, finding similar patterns along equivalent chromosomal regions, even where the underlying DNA sequences are differen...

Jump-starting T Cells In Skin Cancer

...es causes tumor regression without expanding large numbers of vaccine-specific killer T cells. Pierre Coulie...ic T cells after vaccination did not require large numbers of vaccine-specific T cells. Although it is not known how these tumor-specific cells get activated,...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...esearchers found no difference in pancreas size or numbers of pancreatic beta cells, which produce insulin. But cultures of the beta cells revealed the answer: the undernourished mice had an abnormal way of responding to glucose. "They were somehow 'programmed' to secrete a limited amount of insulin later i...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

... stem cells andresulted in the generation of large numbers of DA neurons. In theircurrent JCI study, Jun Takahashi and colleagues generated neurons frommonkey embryonic stem cells and exposed these cells to FGF20, a growthfactor that is produced exclusively in the area of the brain affectedby Parkinson disea...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

... of people are taking protease inhibitors, and the numbers who experience these unexpected side effects are very low -- much less than 1 percent." Co-investigator Michael Ackerman, M.D., Ph.D. agrees that the benefits of the drugs far outweigh the risks. "Our findings should not jeopardize the availability ...

U of M researcher examines newly emerging deadly disease

...uperantigens (bacterial toxins that activate large numbers of T cells), often leading to death due to hypertension and shock. Purpura fulminans has been identified in five cases in the Minneapolis-St. Paul, Minn., metropolitan area during 2000-2004, as described in the April 1, 2005 issue of Clinical Infecti...

Scientists discover the cellular roots of graying hair

...rodents aged and their hair beganturning gray, the numbers of stem cells diminished in proportion to theloss of color. The scientists were surprised to observe that, at thesame time and the same rate, differentiated, pigmented melanocytes wereshowing up in the follicle at the location where the stem cellsres...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

...rodents aged and their hair beganturning gray, the numbers of stem cells diminished in proportion to theloss of color. The scientists were surprised to observe that, at thesame time and the same rate, differentiated, pigmented melanocytes wereshowing up in the follicle at the location where the stem cellsres...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

...rodents aged and their hair beganturning gray, the numbers of stem cells diminished in proportion to theloss of color. The scientists were surprised to observe that, at thesame time and the same rate, differentiated, pigmented melanocytes wereshowing up in the follicle at the location where the stem cellsres...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

... genes appear to be turned on in groups by massive numbers of tags. HOX genes also are deeply involved in cancer, making the findings particularly important. Some of the proteins that regulate HOX genes are capable of causing or suppressing tumors. Technological breakthrough Bernstein has been studying ch...

Taking Aim With Nanoparticle PEBBLEs

...he PEBBLEs a bit more before trying them on larger numbers of rats, and PEBBLE-based cancer treatments for people are a long way off. But "there's no doubt," said Kopelman, "that nanoparticles such as PEBBLEs can do a fantastic job for therapy, diagnostics and a combination of the two." Kopelman's collabora...

Genetically modified natural killer immune cells attack, kill leukemia cells

...ed because researchers were not able to grow large numbers of these immune cells in the laboratory, and becau... "By developing a technique for cultivating large numbers of NK cells from a small blood sample, we made it practical to consider them a potential treatment a...

Placenta Is A Rich Source Of Blood Stem Cells

...we may learn how to grow blood stem cells in large numbers for clinical application.'' Blood stem cells are ...od stem cells appeared in the placenta early, with numbers peaking mid-gestation. Only the fetal liver, where blood stem cells are known to expand tremendously...

Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra

...es on the islands. Mostly arctic foxes and smaller numbers of red foxes were introduced to more than 400 islands. Byrd, who has been involved in restoration efforts in the Aleutian islands since 1971, said most of the islands had major breeding colonies of seabirds before the arrival of foxes. There are abo...

Researchers trace evolution to relatively simple genetic changes

...ill exist in the ocean fish. So we collected large numbers of ocean fish with complete armor, and we found a very low level of this genetic variant in the marine population." So, he said, "the marine fish actually carry the genes for this alternative state, but at such a low level it is never seen;" all the...

Octopuses occasionally stroll around on two arms, UC Berkeley biologists report

...ill exist in the ocean fish. So we collected large numbers of ocean fish with complete armor, and we found a very low level of this genetic variant in the marine population." So, he said, "the marine fish actually carry the genes for this alternative state, but at such a low level it is never seen;" all the...

Development of portable infectious disease detector

... microscopic channels to move and manipulate small numbers ofcells reliably. In the process, the group has ap...that can determine the biologicalactivity of large numbers of compounds with extreme rapidity and socould have a major impact on the drug discovery process.Fif...

Research Gives Hope For Liver Damage

...hampton said: "We arefacing a huge increase in the numbers of patients with advanced liverfibrosis (scarring) and cirrhosis (end stage scarring of the liver).Currently, we have no effective treatment for liver cirrhosis which isassociated with internal bleeding, liver failure and the development ofprimary li...

MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

...used to study realcellular systems, where the huge numbers of potential species andreaction channels makes things very difficult."Computer simulations can be powerful tools in contemporary molecularbiology research, aiding scientists in analyzing data and in testinghypotheses with simulated outcomes before t...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...cell," Handgretinger said. "So if we extract large numbers of sjTRECs from T cells in the blood of a patient about to undergo a stem cell transplant, that's a good sign. It means the patient's thymus is a good T-cell factory." Handgretinger is the senior author of the Blood report. The St. Jude team tested...

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