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Tag: "nuclei" at biology news

Cytoplasm affects the number of vertebrae in carp-goldfish clones

...triguing findings in cloned offspring created when nuclei from one genus of fish were transplanted to enucle...r genus of fish. The seven offspring, cloned from nuclei of common carp and egg cytoplasm of goldfish, were virtually identical to the nuclear donor species,...

Color-blind method opens new doors in DNA sequencing

... sequencing, scientists first extract DNA from the nuclei of cells and through a painstaking series of bacterial cloning and/or polymerase chain reaction (PCR) steps, reduce its length to a manageable size of thousands of nucleotides. Using natural replicating enzymes, the DNA is tagged with four fluorescen...

Nano-Probes Allow an Inside Look at Cell Nuclei

...loped a way to sneak nano-sized probes inside cell nuclei where they can track life's fundamental processes,...biologist can image long-term phenomena within the nuclei of living cells," says Fanqing Chen of Berkeley Lab's Life Sciences Division, who developed the tech...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...cumulation of a protein called beta-catenin in the nuclei of these cells. Kaestner's group had earlier published research on a transcription factor called Foxl1 that is also expressed in the colon, but in a different layer of cells, adjacent to the epithelium, called the mesenchyme. They had seen that mice...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...e tens of thousands of stretches of DNA within the nuclei of cells we call our genes. One thing that has become clear in the last several decades, however, is that while our genes contribute to human health and disease, it is not always the genes themselves that matter, but rather how the genes are control...

Double triumph in stem cell quest

...method starts with an existing human ESC line. The nuclei containing the DNA of the ESCs are removed by spinning them in a centrifuge. Verlinsky would not reveal the details of his technique, but other teams glue cells to a surface and spin them until the denser nucleus is forced out. Then the team take ce...

Cellular Defects in Premature Aging Disease are Reversible

...rotein. Without lamin A holding them together, the nuclei of progeria cells become wrinkled and misshapen. I...geria cells were restored to normal; visually, the nuclei lost their wrinkles and lobes and returned to a natural ellipsoid shape, and the expression of other...

Of mice and men's (and women's) contraceptives

...organisms, ranging from bacteria to humans. In the nuclei of developing germ cells, MSY2 enhances synthesis of a select group of messenger RNA (mRNA) molecules and transports them from the nucleus into the cytoplasm. There, MSY2 proteins stabilize the mRNAs, which are used to make new proteins. Many of thes...

Scientists generate patient-specific stem cells, Science study says

...ersity in Seoul, Korea and colleagues replaced the nuclei from donated oocytes with nuclei from skin cells from male and female patients, ranging in age from 2 to 56, who had spinal cord inju...

SuperLigands - a database of ligand structures derived from the Protein Data Bank

...ersity in Seoul, Korea and colleagues replaced the nuclei from donated oocytes with nuclei from skin cells from male and female patients, ranging in age from 2 to 56, who had spinal cord inju...

Scientists succeed in cloning human embryos from eggs matured in the lab

...chniques, they injected into the empty oocytes the nuclei taken from somatic cumulus1 cells (i.e. non-germ cells) of another person ?a process known as non-autologous nuclear transfer. After time for nuclear re-programming the oocytes were artificially activated by incubation in a medium containing calcium ...

Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005

...chniques, they injected into the empty oocytes the nuclei taken from somatic cumulus1 cells (i.e. non-germ cells) of another person ?a process known as non-autologous nuclear transfer. After time for nuclear re-programming the oocytes were artificially activated by incubation in a medium containing calcium ...

Researchers devise new technique for creating human stem cells

...e human stem cells. SCNT involves transferring the nuclei of adult cells, called somatic cells, into oocytes in which scientists have removed the nuclei. The researchers said that -- while the technique might one day be used along with SCNT, which involves the use of unfertilized human eggs -- technical hu...

Sugar helps control cell division

...that removes the sugar from proteins ended up with nuclei that didn't look right under a powerful microscope. Instead of being disseminated fairly uniformly through the entire nucleus, the genetic material of these cells was bunched up, giving the contents of the nucleus a "wrinkly" appearance. Exactly wha...

Molecular trigger for Huntington's disease found

...vide a molecular mechanism linking disturbances of nuclei and mitochondria in HD." Byoung-Il Bae, Shuichi Igarashi, Masahiro Fujimuro, Nishant Agrawal, Yoichi Taya, S. Diane Hayward, Timothy H Moran, Christopher A Ross, Solomon H Snyder, Akira Sawa: "p53 Mediates Cellular Dysfunction and Behavioral Abnorma...

Scientists find a maturity gene in fly

...e receptors, which in turn attach to genes in cell nuclei to switch the genes on or off. Nuclear hormone receptors are found in all animals, including flies and humans, and are linked to maturation. "So concluding that nuclear receptors are critical for the timing of onset of maturation [in flies] is a log...

MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools

...e receptors, which in turn attach to genes in cell nuclei to switch the genes on or off. Nuclear hormone receptors are found in all animals, including flies and humans, and are linked to maturation. "So concluding that nuclear receptors are critical for the timing of onset of maturation [in flies] is a log...

Scientists get first glimpse at how plants, most animals repair UV-damaged DNA

...ons that lead to diseases such as cancer. In cell nuclei that contain photolyase, the enzyme forms a water-filled pocket with the right shape and size to accommodate the dimer for the repair. Normally, the enzyme wouldn't be able to reach the dimer, which is hidden inside the coiled DNA molecule, Zhong sai...

Research casts doubt on circulating stem cells

...in fact able to detect green-fluorescent stem cell nuclei in the muscle fibre for several months after the b...he next step was to find out whether the stem cell nuclei were actually producing muscle proteins. Here, the results were negative: "If at all, very few nucle...

Mouse genome much more complex than expected

... the genes. The DNA encyclopedia is stored in the nuclei of the cells. If the body is to produce a specific protein, the appropriate page of the encyclopedia is copied (rewritten or 'transcribed'). Only the copies can leave the cell nucleus. They consist of a DNA-like material known as mRNA. Each mRNA cont...

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