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Tag: "novo" at biology news

First demonstration of new hair follicle generation in an animal model

...er can regenerate large portions, but it is not de novo regeneration; some of the original liver has to remain so that it can regenerate.) In this study, researchers found that wound healing in a mouse model created an “embryonic window?of opportunity. Dormant embryonic molecular pathways were awakened...

Blood sugar's manufacture limited by building blocks' supply

...hortage, a condition known as hypoglycemia. The de novo synthesis of glucose depends on the availability of a substrate molecule that comes from an amino acid. The researchers found that mice with a targeted deletion of KLF15 display severe hypoglycemia after an overnight fast. They further found evide...

Cells selectively absorb short nanotubes

...in the critical goal of reducing health risk by de novo engineering of the nanotubes themselves." ...

Pathway toward gene silencing described in plants

... make the DNA accessible for methylation by the de novo cytosine methyltransferase, DRM2. A paradoxical aspect of the pathway is that siRNAs direct DNA methylation but DNA methylation is also required for the production siRNAs. "It's a circular pathway. You have to produce the siRNA in order to have t...

Fat's fate depends on its source

...iet should include an adequate source of fat. "De novo synthesis of fat is an energy-expensive process whose role in adult mammals is poorly understood," said study senior author Clay Semenkovich, of Washington University School of Medicine. "The current study supports the notion that the source of fats ...

B cells are required for development of epithelial cancer associated with chronic inflammation

... K.E., Korets, L.V., and Coussens, L.M. (2005). De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7, 411?23. www.cancercell.org ...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...rentially expressed in ALL cells that exhibited de novo cross resistance to four widely used antileukemic ...ovide new insights into the biological basis of de novo multiple-drug resistance and illuminate potential new targets for overcoming this cause of treatment...

Institute for Systems Biology Symposium Addresses Need for Better Computational Tools

...vices, outlining current efforts to run Rosetta de novo structure prediction on World Community Grid, and ...nknown function in over 60 complete genomes via de novo structure prediction. Other presenters included keynote speaker Dr. Nathan Myhrvold, Founder of Inte...

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