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Tag: "noticed" at biology news

Loss of stem cells correlates with premature aging in animal study

...ers deleted ATR in the tissues of adult mice, they noticed that the mice showed signs of premature aging, such as hair graying, hair loss, and osteoporosis, within three to four months. To be able to renew itself, most tissues have a reservoir of specific adult stem cells. These stem cells don’t divide a...

Runners -- Let thirst be your guide

...gh most cases are mild enough so that they are not noticed by the athletes themselves. “The tragic aspect of the deaths that have occurred from EAH is that these are healthy young people who otherwise would have lived normal, long lives,” says Verbalis, who is also Chief of the Division of Endocrinology a...

Salk scientists hammer out a pathway that promotes muscle cell survival in mice

...n muscle tissue was unknown. Then, the researchers noticed that mice lacking CREB activity in their muscle cells also had a genetic brake, called histone deacetylase (HDAC), stuck in place. Without loosening the brake by a chemical modification process known as phosphorylation, muscle-specific genes could no...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

...e expected antibody response, the researchers also noticed something unexpected. The vaccine enhanced another type of immune response known as cellular-mediated immunity (CMI). CMI allows the immune system to identify, target and kill cells that have already become infected, something antibodies can not do...

Need oxygen? Cells know how to spend and save

...ction at normal oxygen levels. Semenza's team noticed that one particular component of the COX protein complex, COX4, comes in two different forms, COX4-1 and COX4-2. Under normal oxygen conditions, the cells' mitochondria contain mostly COX4-1. The researchers suspected that COX 4-2 might be the active...

Antifungal drug kills TB bug

... at the bug and its DNA content in more detail, we noticed it had some unusual characteristics. In particular, we noted the presence of a very large number of enzymes called P450s, which are usually associated with more complex organisms. "In humans, P450s oxygenate molecules in the body and are essential...

Liver regeneration may be simpler than previously thought

... The results were unexpected. The researchers noticed that only a few proteins were common to both processes. Proteins called transcription factors, which affect DNA in the cell's nucleus, were highly involved in the development of embryos' livers but not in adult liver regeneration. Instead, proteins t...

Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight

...e still did not develop fever, but the researchers noticed that these mice were gaining weight. "The experimental mice were clearly getting heavier than their wild type litter mates, the control mice," says Sanchez-Alavez. "We realized there was something interesting going on with these animals, so we st...

New species declared: Clouded leopard on Borneo and Sumatra

...new species. “It’s incredible that no one has ever noticed these differences.? The new clouded leopard species is generally darker than the mainland species, has small cloud markings, many distinct spots within the cloud markings, grayer fur, and a double dorsal stripe. Clouded leopards from the mainland ...

Einstein's tea leaves inspire new blood separation technique

... an explanation to this phenomenon in 1926 when he noticed that tea leaves collected at the center of the bottom of a stirred teacup instead of being expelled outward. The tiny chamber of blood, like the teacup, is a cylinder of liquid that is rotated at the top while the base remains stationary. To satisf...

Statin plus cancer drug deliver combo punch to brain cancer cells

... them a long life." When the Hopkins researchers noticed that Bcl-2 and hedgehog expression increased in tandem in medulloblastoma cells, they tried adding hedgehog-blocking cyclopamine to the cells and found that Bcl-2 production dwindled and tumor cells died off. Lead author and pathology fellow Eli ...

Bacterial response to oxidation studied as toxin barometer

...est waste in wastewater treatment plants. When she noticed that the useful organisms were being put out of commission by various toxins in the water, she and a student went to a conference of microbiologists who work with stress systems. “We saw a connection between what they were seeing in food processing a...

Genes and genius: Researchers confirm association between gene and intelligence

...ed at three regions of DNA along the gene and also noticed influences on intelligence. In this new study, however, researchers tested multiple genetic markers throughout the gene. "If we look at a single marker, a DNA variation might influence IQ scores between two and four points, depending on which var...

Low levels of neurotransmitter serotonin may perpetuate child abuse across generations

...n brain processes that regulate emotions. We also noticed that about half of the babies exposed to abuse became abusive parents, whereas the other half did not. This is also the case in humans as not all abused children grow up to be abusers." In order to study the possible effects of early abuse on brain...

Gene key to taste bud development identified

...ng other sites. As they worked with the mice, they noticed that specific areas on the tongue and in the back of the mouth lit up, in addition to areas in the esophagus. Further studies, Hogan said, confirmed that SOX2 was present in high amounts during the development of taste buds. In another set of exper...

OHSU researchers demonstrate how white blood cells cannibalize virus-infected cells

...and fluorescently labeled infected cells when they noticed that the T-cells also began to glow with the fluorescent dye. Further investigation revealed that the CD8+ T-cells, often referred to as "killer" T-cells, were literally ingesting parts of the virus-infected cells that they were attacking. Slifka...

Chronic jet-lag conditions hasten death in aged mice

...etween jet lag and mortality by something they had noticed in an earlier, unrelated study: A surprising fraction of old (but genetically altered) rats exposed to a six-hour advance in their light cycle died after the shift in schedule. In the new work, the researchers examined the mortality link in earnes...

Nobel Laureate finds 'elegant' explanation for DNA transcribing enzyme's high fidelity

... of the work, we saw something that had never been noticed before?additional protein density beneath the matching nucleotide,?Kornberg said. The team traced that protein density back to a portion of the polymerase II enzyme: the trigger loop. “Of the 14 crystal structures now reported in which the trigge...

Bones at the nanoscale

...s, and less than a fifth of the strain is actually noticed in the mineral phase. The soft structures form a single rigid unit at the next level and so on, enabling the tissue to sustain large strains. This is why the brittle apatite remains shielded from excessive loads and does not break. The results als...

Researchers link ocean organisms with increased cloud cover and potential climate change

...ally. "While looking at the satellite pictures, I noticed that cloud properties over large phytoplankton blooms were significantly different from those that occurred away from the blooms," recalled Meskhidze, now an assistant professor in NC State's College of Physical and Mathematical Sciences. The Sout...

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