First technology to remove prions that cause vCJD from blood launched
...one from the suffering we had to endure." She also notes that although we should hope for the best, we must prepare for the worst and take every measure available today to safeguard the blood supply. Pall Corporation developed the Leukotrap Affinity Prion filter to help blood authorities around the world ...Potential Drug Target For Treating Cocaine Abuse Found
...ter without inhibiting the transporter by itself," notes Eric Nestler, chair of psychiatry at the University of Texas Southwestern Medical Center in Dallas. "This article reports early studies with just such a compound." Although the results are preliminary, this breakthrough shows that it may be possible...Researchers report new pro-inflammatory role for anti-inflammatory enzyme
...o act principally in an anti-inflammatory manner," notes Dr. Hobbs. "The results of our study show clearly that eNOS can also act in a pro-inflammatory manner and accelerate host-defense in response to pathogenic stimuli." This discovery may eventually lead to new treatments for septic shock and other inf...Silence the gene, save the cell: RNA interference as promising therapy for ALS
... time produce another normal form of the protein," notes Patrick Aebischer, EPFL President and a co-author ...rference-mediated gene silencing in an ALS model," notes Raoul. Because the normal form of the SOD1 protein may be necessary for the survival or function of...First frozen egg baby born in Canada
...n who wish to delay childbearing to do so safely," notes Dr. Tan. After 30 years of age, a woman's fertility declines and the rate of spontaneous abortion increases significantly. The risks of chromosomal abnormalities, such as Down's syndrome, are also higher in babies produced by older women. Finally, cu...GeneNotes - A novel information management software for biologists
...nvironment for users to surf the Internet, collect notes for genes/ESTs, and retrieve notes. GeneNotes is supported by a server that integrates gene annotations from many major databases (e.g., HGNC, MGI, etc.). GeneNotes uses the integrated gene annotations to (a) identify genes given various types of gen...Scientists discover how plants disarm the toxic effects of excessive sunlight
...en and defend itself from this toxic substance. He notes that the response mechanism is likely highly conserved across species from microbes to plants and humans - and therefore very applicable to other fields of study. For example, too much sunlight can actually be harmful to plants, because the heighten...Bird Brains Show How Trial and Error May Contribute to Learning
...ut a tiny burst of electricity would show up a few notes later as a change in volume or pitch at a particular time in the song. The variations are usually too subtle for human ears, Kao said, but sensitive recording equipment can detect them. The systematic trials were possible with the aid of a computer ...MetaChip provides quick, efficient toxicity screening of potential drugs
...artners use measures to prevent HIV transmission," notes NIAID Director Anthony S. Fauci, M.D. "If effective, microbicides would be a valuable woman-controlled means of slowing the pace of the HIV/AIDS epidemic," Dr. Fauci adds. The first volunteers were enrolled this week at sites in Durban, South Africa...International trial of two microbicides begins
...artners use measures to prevent HIV transmission," notes NIAID Director Anthony S. Fauci, M.D. "If effective, microbicides would be a valuable woman-controlled means of slowing the pace of the HIV/AIDS epidemic," Dr. Fauci adds. The first volunteers were enrolled this week at sites in Durban, South Africa...New SARS Protein Linked To Important Cell Doorway
...ty to isolate the virus and grow it in a culture," notes lead author Daved Fremont, Ph.D., assistant professor of biochemistry and molecular biophysics and of pathology and immunology. "Now we can take these viral genetic sequences, which can be attained very rapidly, and get a head start on detailed bioph...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
...ferent things involves which genes are turned on," notes Bradley Bernstein, a pathologist at Harvard Medical School. He is also a research associate at the Broad Institute of Harvard and M.I.T., where a complex analysis of packaging of two entire human chromosomes was done for the first time. Besides Bern...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...Behavioral Qualities of Pan and Peter Pan Epstein notes that this research is conceptually new since he suggests that a single gene can both tell a cell what it should become and restrict its fate by preventing differentiation. The ability of a single biochemical factor or complex of factors to have this ...Elusive HIV shape change revealed; Key clue to how virus infects cells
... that inhibit the shape change," says Harrison. He notes that some HIV inhibitors already in development se...nter a cell before the immune system can "see" it, notes Harrison. "We can now compare the bound and unbound forms and try to understand whether there are a...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
...re tumors get started in the mice with extra IGF2, notes Feinberg. "In the mice, loss of imprinting of IGF...an Longo, M.D., of the National Institute on Aging notes that the mice with both double IGF2 and the APC mutation should be a useful animal model to evaluate...