Simulations unravel outer membrane transport mechanism
...s the outer membranes of Gram-negative bacteria is not a simple task. The cells must be selective in what substances they take up, and the outer membrane contains no energy-generating machinery to power the job of hauling large molecules inside. The new study examined an outer membrane transport syste...New study reports hotel guests at risk from carbon monoxide poisoning
...e 1989, their use in hotels, motels and resorts is not widespread. In fact, while every guest room in the...er of reported incidents of poisoning per year has not decreased over this 15-year interval…While the risk of CO poisoning from a one-night stay to an indi...Crammed with charged DNA, pressure rises inside virus
...nation of positively charged ions, the virus could not force all of its DNA into the capsid.” The researchers discovered that the forces in the capsid are slightly higher than predicted by theoretical calculations. They say this may be because the packed DNA is less ordered than assumed in the calcul...Snoring in children might be an allergic type disease
...f more serious sleep-disordered breathing, so it’s not necessarily a harmless condition,” Dr Marshall added. “In adults habitual snoring is seen as being caused by anatomical problems in the airway or obesity. But in children it seems that snoring is much more closely related allergy and inflammation”. ...CSIRO scientists join fight to save 'Tassie devil'
...ssie devil to survive the DFTD threat was crucial, not just because it is a major tourism attraction but also to ensure devils continue to play the vital role they have in maintaining Tasmania’s environmental balance. Other collaborators include: the Department of Primary Industries and Water (DPIW) ...A new plant-bacterial symbiotic mechanism promising for crop applications
... The first observation was that the bacteria did not penetrate the roots of its host-plant by the hairs. It took advantage of “crack zones” comparable with wound areas. The set of results obtained from subsequent work, seeking to identify the genes involved in producing the unknown signal molecule that...Hormone helps mice 'hibernate,' survive starvation
... and causes torpor. In properly fed mice, FGF21 is not normally active; however, when the researchers introduced FGF21 into these mice, the animals’ metabolism changed. “When mice were given this hormone, their metabolism appeared as if they were starved, even after they had just eaten,” said Dr. Klie...Research team identifies new Alzheimer's gene
...xtremely rigorous criteria to determine whether or not their volunteers had Alzheimer’s. For instance, the study included more than 1000 brain donors confirmed to either have Alzheimer’s disease or be free of the disorder at autopsy. This study resulted in a comprehensive set of high-quality data to be m...How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of 'fullness'
...he average for mice of their size and age who were not being given the compound. The peptide has been patented in Europe and the U.S., and a commercial firm, Bioline RX Ltd. Of Jerusalem has purchased development rights from Yissum, the Hebrew University’s technology transfer company, and is current...Envisat captures first image of Sargassum from space
...y productivity. "The 709 band used by MERIS is not present on other ocean-colour sensors. It was essential to our detecting Sargassum," Gower said. "The MCI index has allowed us to find so many interesting things, including Sargassum and Antarctic super blooms. It really gives us a new and unique vie...Dirty snow may warm Arctic as much as greenhouse gases
... on emissions can prevent further warming but does not produce immediate cooling....Largest synthetic gene ever built offers insights into anti-malarial drug resistance
... gene PfNHE likely contributes, and this turns out not to be as vital as PfCRT. Now, based in part on this study, they know that PfMDR1 is dependent on mutated PfCRT, and probably doesn't act independently. "The contribution of PfMDR1 to anti-malarial drug resistance is important, but much smaller th...Loss of stem cells correlates with premature aging in animal study
...had an overwhelming amount of DNA damage and could not contribute to tissue renewal; nevertheless, the 10 to 20 percent of cells that escaped ATR deletion were able to reconstitute tissues in the engineered mice, at least initially. “Think of aging as a slow loss of stem cells, a deterioration of po...Pesticides choke pathway for nature to produce nitrogen for crops
...n is reduced. If this natural fertilizer source is not replaced by increased application of synthetic nitrogen fertilizer, then crop yields are reduced and/or more growing time is needed for these crops to reach the yields obtained by untreated crops. We feel that this is a previously unforeseen factor c...Caribbean frogs started with a single, ancient voyage on a raft from South America
...ral America. The scientists speculate that it may not be coincidental that these ancient and successful ...er and insect food for frogs," Hedges said. It is not likely that the frog species dispersed simply by swimming because frogs dry easily and are not very ...Study shows big power of small RNAs, not just proteins, in halting cancer
...ion among different CSHL research laboratories has not only found that p53 can arrest the growth and even eradicate cancers, but we’ve revealed something very surprising about what makes this pathway so powerful,” said Hannon. CSHL research published by Nature earlier this year, concluded that even in th...Studies to find better ways to preserve human eggs, ovarian tissue under way
...ional cryopreservation freezes the liquid part but not the cells inside. Liquid freezes and the water ins...age 18-42 that would be discarded because they are not adequate for in vitro fertilization. They also are retrieving and maturing eggs from cow ovaries don...Millions of children denied drug that costs less than $3 a year
...y healthcare delivery system, which should provide not only reliable supplies of drugs, with adequate facilities for storage and dispensing, but also educational programmes for health practitioners and the general population, he concludes....In mice, drug protects against diabetes and atherosclerosis
...nsume dangerously fatty foods. Use of the compound not only appears to prevent the development of these d...hough Hotamisligil cautioned that experiments were not designed to look for such effects rigorously. While it is not certain that the experimental compo...... find the CPAP device cumbersome, many patients do not use it consistently or for long enough periods while sleeping. In the current study, for example, patients used CPAP on average about 5 hours a night. The researchers found that although daytime sleepiness could be improved after 4 hours to 6 hours ...