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Tag: "normal" at biology news

Molecule that destroys bone also protects it, new research shows

...ne loss caused by periodontal disease, compared to normal mice. "What’s the difference between an autoimmune disease like RA and periodontal disease" Periodontal disease is an infectious disease, and as with most infectious diseases, white blood cells of the innate immune system called neutrophil...

UCLA AIDS Institute researchers find a peptide that encourages HIV infection

...monkeys have all three. "Here's a peptide whose normal structure allows it to protect against viruses, yet if you make the same peptide and place its amino acids in a reverse order, that lets the virus in," Lehrer said. "We would like to learn why it happens, but at the moment there's no explanation for ...

World's leading scientists announce creation of 'Encyclopedia of Life'

...over things so numerous or vast they overwhelm our normal vision." Scientists began creating individual web pages for species in the 1990s. However, Internet technology needed to mature to allow fast and efficient creation of a comprehensive Encyclopedia. While specific Encyclopedia of Life efforts, in...

Percutaneous aortic valve replacement safe, successful in high-risk patients

...rta in a direction opposite, or retrograde, to the normal flow of blood. Once the catheter is properly positioned in the opening of the aortic valve, it is pulled back to release the CoreValve, a self-expanding stent-like frame with the new tissue valve attached to its core. As it expands, the CoreValve cov...

Study offers clues to 'Broken Heart Syndrome'

...within a few weeks. Heart function was found to be normal in 29 of 30. Dr. Regnante said that long-term follow-up will be critical to improved understanding of Takotsubo cardiomyopathy. In addition, he and his colleagues are gathering information on patients who have intravascular ultrasound during card...

Scientists develope a new model of artificial canine skin

...d an artificial canine skin model, very similar to normal skin, which is useful for research and which repre... follows the same pattern of expression as that of normal canine skin, even forming a basal membrane, which also maintains the characteristics of conventional...

DNA-damage test could aid drug development

...rsor cells to proliferate and differentiate in the normal way, dividing four or five times before losing the...the toxic agents than were the cultured cells from normal mice, further confirming the results. With the new assay, "instead of testing one chemical and on...

Sleepless for science: Flies show link between sleep, immune system in Stanford study

...y the same light and temperature conditions as the normal flies. They looked at flies that were defective in one of two genes, called "timeless" and "period". They found that the loss of either gene's function made the flies more sensitive to bacterial infections and these sick flies died significantly f...

Herpes infection may be symbiotic, help beat back some bacteria

...Chronic virus infections may in part define what a normal human immune response is," says Virgin, who is the Edward Mallinckrodt Professor of Pathology and Immunology. "We may need to think about that as we consider the implications animal model results hold for human diseases." Scientists have recognize...

Effect on breast tumors of DNA alternations in 3 genes described

...lation is a process that causes genes that promote normal cell growth to produce proteins that cause malignant behavior, or unregulated cell growth. Until now, data has been very limited regarding the mechanism and causes of hypermethylation, especially for hypermethylation in breast cancer. The purpose of...

First demonstration of new hair follicle generation in an animal model

... a way that has less scarring and includes all the normal structures of the skin, such as hair follicles and oil glands, rather than just a scar,?explains Cotsarelis. By introducing more wnt proteins to the wound, the researchers found that they could take advantage of the embryonic genes to promote hair...

Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys

... the dopaminergic cells (that usually exist in the normal brain but in lower quantities). Amongst these trophic factors is the GNDF (Glial Cell-derived Neurotrophic Factor). Cells extracted from the carotid body have been used as a source for dopaminergic cells in the treatment of Parkinson's disease in ...

Gene thought to assist chemo may help cancer thrive

...3 were still alive after five years. Patients with normal p53 displayed only a 30 percent survival rate. The...had a much better survival rate than those who had normal p53. In the study, researchers took malignant and benign ovarian tumors straight from the operati...

Peanut allergies overstated, study finds

...are allergic. "If the child is able to tolerate normal amounts of peanut every day then the result of any peanut allergy test is irrelevant." Allergy practitioners may need to interpret results of allergy tests in the context of their own practices, the researchers found. "If there is a positive re...

Executable biology -- Computer science sheds light on animal development

... our understanding of cancer metastasis as well as normal development. Traditional biological models give a fairly static picture of cellular processes, and this limits understanding of the details involved. Biologists and computer scientists from the EPFL (Ecole Polytechnique Federale de Lausanne) and ...

Switching genes to overdrive improves muscular dystrophy symptoms in mice

...y in cells. PGC-1alpha is also required for the normal operation of genes that control the development of...ed PGC-1alpha activity performed almost as well as normal mice on the first day; their performances decreased on the second day, but they still did better tha...

Fast and slow -- How the spinal cord controls the speed of movement

...example, medical researchers need a template for a normal spinal cord in order to know if nerves are re-growing normally, Fetcho said. In Parkinson’s disease, researchers believe that a neurotransmitter released by brain cells may contribute to activating a system of nerves and muscles that allow for fas...

Revealing the machinery underlying the 'plastic' juvenile brain

...critical period. For example, children deprived of normal visual stimulation during an early critical period...the researchers exposed the animals to episodes of normal light and analyzed the response in the genetic machinery of the visual cortex in each animal's brain...

Brain maps online

...enable better understanding of the organization of normal brains, and could help researchers in identifying fine morphological and chemical abnormalities underlying Alzheimer's, Parkinson's and other neurological diseases, Mikula said. To make the maps, the researchers started with sections of brain mou...

Discovery of 'master switch' for the communication process between chloroplast and nuclei of plants

...a way that the plant won’t completely suppress its normal metabolisms and activate all of its stress metabolisms when faced with a lot of stress. If you want to generate a plant that is more tolerant, you need to deal with these two things." Added Koussevitzky: "We’re trying to put the signaling pathways ...

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