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Tag: "normal" at biology news

HIV dementia alarmingly high in Africa

...avioral and motor disabilities that interfere with normal daily life and in extreme cases lead to total disa...e infection. Treatment can even restore completely normal cognitive function to some of those affected. The study looked at 178 subjects in Kampala, Ugand...

Common cold virus may kill breast cancer cells

...rapy and radiation treatment, which also impact on normal body cells. "In theory, the virus is able to sele...er cells, including breast cancers, whilst leaving normal cells unaffected," she said. Debilitating symptoms associated with conventional treatments (such a...

Decoy pill saves brain cells

...eptor, mGluR1?, the situation is even worse. Under normal conditions, this receptor is neuroprotective. However, calpain truncates it and makes it neurodegenerative in such a way as to start a positive feedback loop that leads to ever-higher levels of calcium and continuous calpain activation. In additio...

Prion disease treatable if caught early

...to discriminate novel objects in their cage and on normal burrowing behavior. In both cases, deficits in those abilities appeared early in the disease. Also, studies of the animals?brain tissue revealed a parallel impairment of signaling among brain cells. However, when the researchers manipulated the an...

White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells

...und that white blood cells in these mice overwhelm normal defenses of cancer cells. In a report in Cancer I... cancers in ordinary mice and also protected those normal mice from what should have been lethal doses of highly aggressive new cancers. But while pursuing...

Researchers show that veins stiffen as we age

...pressure are stiffer than the veins of people with normal blood pressure. Two doctoral students, Erin Delaney and Megan Wenner, are assisting with this portion of the research, which will examine both young and older adults with high blood pressure. While high blood pressure is all too common among older ...

A potential biological cause for sudden infant death syndrome

... brain so that the baby doesn't asphyxiate. "A normal baby will wake up, turn its head, and start breathing faster when carbon dioxide levels rise," explains Kinney. But in babies who die from SIDS, defects in the serotonin system may impair these reflexes, the researchers believe. Kinney previous...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...be used to return severely failing hearts to their normal function, potentially removing the need for heart transplantation, according to new research. The mechanical devices, known as Left Ventricular Assist Devices (LVADs), are currently used in patients with very severe heart failure whilst they await t...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...lifespan of a variety of species by reducing their normal food consumption by 30 to 40 percent - a diet known as calorie restriction. Through this research, scientists identified Sir2 as a key contributor to life extension. Without Sir2, for example, fruit flies see none of the benefits from either calorie...

Antibiotic inhibits cancer gene activity

...ound that siomycin A induced cancer cells, but not normal cells, to commit suicide in a process called apoptosis. The new screening technique, Gartel said, gives researchers a rapid way to find agents that target oncogenes -- genes believed to cause cancer. He said siomycin A, the first compound found wit...

How fish mend a broken heart

...itor cells can restore cells lost in the course of normal organ function or after minor injury but cannot regenerate after major damage or removal of structures. "It is believed that the capacity for regeneration is an ancestral condition that has occasionally been lost in the course of vertebrate evoluti...

Osteoarthritis may be sign of faster 'biological ageing'

...the unstable molecules produced as a by-product of normal bodily processes, as well as external factors, such as tobacco, alcohol, and sunlight. Osteoarthritis is the most common form of arthritis, with the hands being one of the sites most often affected. Its frequency rises dramatically with age, but it...

New study aims to stop sepsis in its tracks

...percent of them die. Sepsis occurs when the body's normal reaction to an infection goes into overdrive, causing widespread inflammation and dramatic changes in body temperature, blood pressure, breathing, and heart rate. It can lead to the malfunction or failure of several major organs. "The goal of this ...

Interaction between lymph and liver cells may affect immune response

...titis C. "As well as providing insight into the normal immune system, our observations might have implications for liver conditions associated with altered LSEC morphology and in particular those conditions associated with loss of fenestrations such as cirrhosis and old age," the authors conclude. "We ha...

Signal protein shows promise for blocking tumor promoters in skin cells

...ains of mice with high levels of Srcasm, which had normal skin, and other strains that over-expressed the Src-kinase called Fyn, which resulted in uncontrolled cell growth with thick, scaly, hairless plaques on the skin. These plaques, or lesions, resembled precursors of cancer. Breeding experiments with th...

Unique gene regulation gives chilly bugs survival advantage at bottom of the world

...teins and are therefore prepared to respond to the normal kinds of challenges that they face in the harsh Antarctic environment. But the adults produce these proteins only when directly confronted with an environmental challenge. "Clearly there is some kind of developmental switch that happens between the...

Why don't all moles progress to melanoma?

...sults of the U-M study ?involving melanocytes from normal human skin and biopsies of non-malignant human mol...alignant skin cells. "By comparing what happens in normal melanoctyes with what happens in melanoma, we may be able to come up with events that are specific f...

Living view in animals shows how cells decide to make proteins

...ptor 2 (FGFR2). This gene plays a critical role in normal mouse and human development, and the order in which its RNA is assembled can alter an animal’s development. As a model system to study, the scientists genetically created a "glowing" mouse. The mouse carried in its FGFR2 gene a green fluorescent t...

With fruit fly sex, researchers find mind-body connection

...result, these mutant females are not recognized by normal males and these mutant males are not recognized by normal females ?and none of the mutants can mate. So this makes it difficult for scientists to categorize t...

Chronic jet-lag conditions hasten death in aged mice

...tly higher death rates than did old mice kept on a normal daylight schedule over the same eight-week period....old mice. While 83% of old mice survived under the normal schedule, 68% survived under the backward-shift regimen and 47% survived under the forward-shift reg...

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