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Tag: "nitric" at biology news

Statin treatment improves spatial memory in mouse models of Alzheimer's

...n this study, Dr. Morcos found that nNOS (neuronal nitric oxide synthase) levels were significantly higher i...he cortex. nNOS is responsible for the release of nitric oxide, a substance that causes dilation of the blood vessels in the brain, which eventually will inc...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

...e researchers have shown that specialized forms of nitric oxide called SNOs may be the key to a problem that...esearchers believe that the presence or absence of nitric oxide or SNOs determines whether these receptors continue to function properly. This action is contr...

Premature births may be linked to seasonal levels of pesticides and nitrates in surface water

... and pesticides can disrupt endocrine hormones and nitric oxide pathways in the developing fetus," he said. "I believe this work may lay the foundation for some of the most important basic and clinical research, and public health initiatives of our time. To recognize that what we put into our environment...

Fat overrides effects of vitamin C

...ds by converting the nitrosating species back into nitric oxide (NO). However, NO diffuses rapidly to lipids, where it reacts with oxygen to reform nitrosating species. The presence of lipids therefore overrides the protective effect of vitamin C against the formation of harmful compounds....

Studies force new view on biology of flavonoids

...hat flavonoids increase the activation of existing nitric oxide synthase, which has the effect of keeping blood vessels healthy and relaxed, preventing inflammation, and lowering blood pressure ?all key goals in prevention of heart disease. Both of these protective mechanisms could be long-lasting compar...

Erectile dysfunction in diabetes is due to selective defect in the brain

... erection. The investigators also examined central nitric oxide (NO within the PVN) which plays an important role in the neurotransmission of normal penile erection. Penile erection is a behavioral response that occurs in response to the administration of N-methyl-D-aspartic acid (NMDA) within the PVN. ...

Flavanols in cocoa may offer benefits to the brain

...ralleled by an increase in the circulating pool of nitric oxide, a critical molecule in the circulatory system that helps dilate blood vessels and keeps them pliable. Hollenberg fed flavanol-rich cocoa to healthy volunteers who were over age 50 and observed a “striking blood flow response?that evolved ove...

Active ingredient in common Chinese herb shown to reduce hypertension

...to measure arteriolar diameter and peri-arteriolar nitric oxide concentration. Results Tanshinone IIA...circulation via enhanced expression of endothelial nitric oxide synthase. The topical application of tanshinone IIA at one ¦Ìg/ml and five ¦Ìg/ml caused signi...

It's in your head: The brain's own globin defends you from shock and stroke

...uggest that neuroglobin is more likely to usher in nitric oxide to protect neuron survival and recovery in areas where oxygen supply is reduced. "Understanding that our brains have a hemoglobin-like molecule in our head that protects and helps restore function in the brain is an important step toward hel...

Heart smart: new drug improves blood flow

...kage occurs, the cells lining the arteries produce nitric oxide to signal to the arterial muscles that they need to dilate the artery and allow more blood through. But free radicals destroy a key enzyme that allows the arterial cells to respond in this way, so the signal doesn't get through. However, the ...

Need to pull an all-nighter?

... from new research showing that preventing the gas nitric oxide from building up in the brain may ward off t...r previous observations about sleep and finds that nitric oxide production in a specific region of the brain ?the basal forebrain ?is both necessary and suffi...

'Erectile dysfunction' drugs heighten natural anti-cancer activity

...team says boosted levels of the chemical messenger nitric oxide appear to dampen the effects of a specialize...rello and his colleagues found that tumors exploit nitric oxide-producing immune cells to create a sort of "fog" that keeps them hidden from white blood cells...

Plant-derived molecules, genetic manipulation point to future chemoprevention methods

...nhibited inflammation in a number of ways: halting nitric oxide production, blocking cyclooxygenase and nitric oxide expression, curbing proliferation and inducing apoptosis in human lung cancer cells. They t...

Therapeutic role found for carbon monoxide

...oth muscle cells: It was relying on a second gas, nitric oxide (NO), for assistance. "When we first start...ls must be present ?and be able to generate NO via nitric oxide synthase [NOS3] -- in order for CO to induce the death of the smooth muscle cells and reverse ...

Gene therapy prevents the onset of diabetic symptoms in mice

...id by one-third since its high point in the 1960s, nitric acid from automobiles has not significantly declined. This research was supported by the National Science Foundation and the Hubbard Brook Ecosystem Study. ##...

Acid rain causing decline in sugar maples, say researchers

...id by one-third since its high point in the 1960s, nitric acid from automobiles has not significantly declined. This research was supported by the National Science Foundation and the Hubbard Brook Ecosystem Study. ##...

Study links high levels of nitric oxide to infertility and sperm DNA damage

...eh Hospital, Hamadan, Iran, said: "In recent years nitric oxide (NO) has been recognised as a molecule that ... there were significantly higher concentrations of nitric oxide in the seminal plasma of infertile patients than in healthy men. High concentrations of NO wer...

Ammonia-loving archaea win landslide majority

...s the measured amounts of greenhouse gases such as nitric oxide and nitrous oxide are not produced by bacteria, but by a very different group of organisms, namely archaea," said Schleper. "But it is not clear, if and in what amounts the archaea form these gases as byproducts. This is only known from some of...

Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's

...ase, overproduction of free radicals, specifically nitric oxide (NO), causes inhibition of PDI by a reaction called S-nitrosylation, thereby reducing PDI's neuroprotective benefits. This data provides the first molecular link between NO free radicals and protein misfolding, which is currently thought to be...

Brain's own cannabis compound protects against inflammation

... suppresses the production of inflammation-causing nitric oxide, which would otherwise cause brain injury. The researchers concluded that the release of AEA in injured brain tissue might act as a "gatekeeper" and an important "negative-feedback loop within the CNS [central nervous system] immune system nee...

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