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Tag: "nicotine" at biology news

Controversial drug shown to act on brain protein to cut alcohol use

Medicationagainst nicotine addiction is nowadays readily available. However, asimilar and equally dangerous addiction, alcoholism, can't yet becontrolled by drugs. Or can it be? Researchers from the University ofCalifornia in San Diego identified a natural compound able to blo...

Drug That 'Tags' Decision-making Areas Of The Brain May Aid

...to areas of the brain that havebeen implicated in nicotine addiction may help studies of people battling othe...vior,developed Nifrolidine to measure a subtype of nicotine receptors in theliving brain by using an imaging technique, positron emissiontomography, more common...

Chemists identify immune system mechanism for methamphetamine binges

...emist at Scripps. Other drugs of abuse, including nicotine and ecstasy (which is structurally similar to methamphetamine), might share a similar mechanism of action involving immune system recognition and a consequent rise in tolerance to the drug, Janda and his associates theorize. Tolerance refers to the c...

Brain Scan Study of Smokers Reveals Signature of Craving

...smokers quit." While scientists have thought that nicotine is the primary agent responsible for cigarette addiction, recent evidence suggests that conditioned responses to sensory cues also play an important role, McClernon said. Brain imaging studies of smokers have found increases in brain activity in resp...

OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies

...ious research by the Spindel lab demonstrated that nicotine is a key cause of these lung development problems. Specifically, nicotine crosses the placenta where it interacts with cells in the unborn infant's developing lungs. While p...

Nicotine triggers the same brain reward circuitry as opiates

...experiments with mice, researchers have found that nicotine triggers the same neural pathways that give opiate...t with the drug's reward. However, unlike opiates, nicotine does not directly activate the brain's opiate receptors, but activates the natural opioid reward pat...

Environmental tobacco smoke linked to behavior problems in children and pre-teens

...en's blood. Cotinine is a substance produced when nicotine is broken down by the body and can be measured in blood, urine, saliva and hair. It is considered the best available marker of environmental tobacco smoke exposure. Dr. Yolton found a relationship between cotinine levels and increases in acting out...

Researchers test new way to quit smoking

...staying smoke-free if they begin using replacement nicotine patches or gum in the weeks before they quit cigar...eir cigarettes and immediately replace them with a nicotine substitute, such as nicotine patches or chewing gum. But some recent small-scale studies have sugge...

Team discovers possible 'universal strategy' to combat addiction

...iences and Engineering Research Council, looked at nicotine and THC (the active ingredient in marijuana). However, Zhang says the results could also hold true for other drugs such as cocaine, heroin, and even methamphetamine. Zhang's U of S research team is part of the Neural Systems and Plasticity Research ...

Cigarette smoke blocks cell repair mechanism, University of Florida study shows

... the Journal of Biological Chemistry revealed that nicotine activates a protein in cancer cells that helps them live long, spread to new sites and grow resistant to chemotherapy. Narayan's team has previously studied cells that were exposed to the chemicals found in cigarette smoke yet did not die. In gener...

Nicotine exposure during development leads to hearing problems

...elieve they have evidence that not only implicates nicotine as the culprit, but also shows what the substance ...havior, and colleagues from UC Irvine, showed that nicotine exposure during the equivalent of a human's third trimester led to hearing-related cognitive problem...

Blood test predicts success of quitting smoking using the nicotine patch

... enable doctors to predict which smokers using the nicotine patch are likely to experience the least amount of...lood test, which is a measure of the rate at which nicotine is metabolized, may eventually be performed non-invasively using saliva or urine samples. "The ultim...

Quitting smoking improves lung function considerably

...moking and completed the six-week study, five used nicotine patches, one employed acupuncture and four quit without any aid. The researchers believe that their findings highlight the importance of smoking cessation for adults with asthma. ...

Dissecting the machinery of nicotine's reward

Understanding what makes people crave the high of nicotine is a key to developing treatment for this highly a...ing involves tracing the neural machinery by which nicotine switches on the brain's reward machinery. In an article in the June 15, 2006, Neuron, Jean-Pierre C...

Smokers invite to test vaccine against nicotine addiction

...e that enlists help from the immune system to keep nicotine away from the brain. The vaccine is designed to h...ed by Nabi Biopharmaceuticals to prevent and treat nicotine addiction and to help people quit smoking. Normally when a smoker inhales, nicotine is carried by th...

Smoking changes brain chemistry

... on the relationship between brain metabolites and nicotine dependence," said Okan Gür, M.D., from the Departm... six months later. Patients were encouraged to use nicotine patches during the initial six weeks of smoking cessation; however, only 36 of the patients complied...

Cigarette smoking impedes tendon-to-bone healing

...njury in rats, the research team found exposure to nicotine delays tendon-to-bone healing, suggesting this cou...ic conditions, but several studies have shown that nicotine interferes with healing of bone fractures and also inhibits bone fusion processes -- many spine surg...

Successful lung cancer surgery not enough to break nicotine dependence in many smokers

...nclude patients believed to be highly dependent on nicotine - so it included only patients who smoked within ...earch, the investigators hypothesized that greater nicotine dependence, a younger age, lower income, and a lower level of education would be associated with a g...

A new target for painkillers

...ls and are in the family of receptors activated by nicotine from cigarette smoking. Alpha9alpha10 nicotinic receptors are found in a variety of body tissues, including white blood cells and the dorsal root ganglia ?a group of nerve cells near the spine and involved in pain transmission. The new study sh...

Fruit fly study identifies gene mutation that regulates sensitivity to alcohol

...also altered the flies' sensitivity to cocaine and nicotine as well. Because this gene variant affected the behavioral response to substances of abuse, the researchers dubbed it white rabbit--a reference to the title of a 1960s song about drug-induced changes. "This study describes key molecular pathways...

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