Study in Science holds promise for a new approach to drug therapy
...ling on the inside. Early studies suggest that the newly discovered "drug candidates" can provide better control of pathways involved in pain relief, inflammation and heart disease, while leaving healthy functions in place. "We believe we have discovered a new class of drugs that could make current drugs...New cellular flaw found in some virulent breast cancers
... interaction of a certain mutated oncogene and the newly described growth control flaw is seen in about 10 percent of breast cancers ?and the deadliest ones. The cancer results from a cascade of molecular events. The overproduction of a common protein, cyclin D1, hyperstimulates a growth switch, CDK4 kina...Newly discovered protein kills anthrax bacteria by exploding their cell walls
...boratory at Rockefeller University suggests that a newly discovered protein could be used to fight anthrax infections and even decontaminate areas in which anthrax spores have been released. "Anthrax is the most efficient biowarfare agent. Its spores are stable and easy to produce, and once someone inhale...Scientists one step closer to cancer vaccine
...ng a treatment for advanced tumour diseases." The newly published study is a continuation of an original discovery that first identified the TEIPP-T cell and that was presented in Ms Wolpert's doctoral thesis at Karolinska Institutet in 1998. The spread of tumours, or metastases, is the most common cause...Bocavirus infection may be associated with pneumonia in Thailand, especially in children
The newly identified human bocavirus was found in nearly 5 percent of pneumonia patients in rural Thailand, mostly in very young children. Researchers from the Centers for Disease Control and Prevention report their findings today at the International Confere...Researchers use dirt to stay one step ahead of antibiotic resistance
...tory studies of clinical situations. By screening newly developed drugs for resistance in soil bacteria, not only can pharmaceutical companies can gain a better understanding of what may emerge in the future as clinical problems, but sufficient warning can be given to hospital microbiology laboratories, p...Powerful technique for multiplying adult stem cells may aid therapies
...emselves, they died. When he mixed them with these newly discovered cells, they thrived. But how did these ...form to search for genes that were active in these newly discovered cells, but not active in similar neighboring cells. Some such genes, he reasoned, might e...Immune system response to viral DNA is unique
...tant question raised by these findings is how this newly described system avoids responding to genomic DNA that is contained within all cells. "If this 'tolerance' to self DNA were to break down, cells might mount an antiviral response against their own DNA," he said. "Further characterization of this pat...Terahertz imaging may reduce breast cancer surgeries
...e of Radiology. Researchers used light waves in a newly explored region of the electromagnetic spectrum--the terahertz region--to examine excised breast tissue and determine if the removed tissue margins were clear of cancer, with good results. This technology has the potential to eliminate the need for m...Common bacteria pirate natural mechanism to get inside cells
.... Daaka says. Receptors can either stay inside the newly created vesicle and be degraded or resurface to be activated once again. Bacteria and viruses also want inside cells and out of the direct line of fire of the immune system or treatments such as antibiotics for bacterial infections, Dr. Daaka says. ...Mining for gems in the fungal genome
...nown in this widely studied fungal species. The newly discovered secondary metabolite gene clusters are already beginning to yield potentially useful medical agents. The team found an anti-tumor agent never before seen in Aspergillus nidulans. "It's just one of many [secondary metabolites to discover]...Rice bioengineers pioneer techniques for knee repair
...s that aren't naturally found in the body. In the newly reported findings, Athanasiou and postdoctoral researcher Jerry Hu, using nothing but donor cells, grew dime-sized disks of cartilage with properties approaching those of native tissue. In a follow-up study due for publication soon, graduate student ...Three new species of lemurs identified
...istinct species within the former L. dorsalis. The newly identified species live in different geographic areas, separated by rivers, but show no obvious morphological differences. ...'Banana-jawed' fossil mammal linked to rare sound-producing skill
...ers, the Duke team measured tooth samples from the newly available fossils. "We looked first at molar teeth, which are used for grinding food, and found that all of them in our specimens were identical, so we were pretty sure they were from the same species," DeBlieux said. "But only half of the fossils h...Cortex matures faster in youth with highest IQ
...arch for gene variants that might be linked to the newly discovered trajectories. However, Shaw notes mounting evidence suggesting that the effects of genes often depends on interactions with environmental events, so the determinants of intelligence will likely prove to be a very complex mix of nature and ...New evidence questions the simple link between prion proteins and madcow disease
While newly published research confirms that under laboratory circumstances prion-protein can be absorbed across the gut, it also shows that this is unlikely to occur in real life. In addition, the results show that the places in the gut that do take up these di...Animal models show that anabolic steroids flip the adolescent brain's switch for aggression
...ggressive. Even after the drug was withdrawn, the newly vicious hamsters attacked, bit and chased the intruders. In fact, their aggressiveness measured ten times greater than that of control hamsters injected with oil only. Their full-blown aggression ?clearly drug-induced -- lasted for nearly two weeks...Sooner is better with cochlear implants, Stanford scientist shows
...ren with cochlear implants were able to meld their newly acquired hearing capability with their ability to read lips. In other words, did their brains process speech the same way as people who are born with the ability to hear? In the Dec. 5 online edition of the Proceedings of the National Academy of Sci...Researchers develop new method to help find deadly malaria parasite's Achilles heel
...port in the Nov. 3 issue of Nature a comparison of newly discovered protein-interactions in Plasmodium falciparum with protein interactions reported earlier in four other well studied model organisms -- yeast, a nematode worm, the fruit fly, and a bacterium that causes digestive-tract ulcers in humans. The...