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Tag: "newly" at biology news

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...o clinicians who are unsure whether to treat their newly diagnosed patients with surgery alone, he said. "This protein profile might be used to identify groups of patients who, independent of stage, should be offered adjuvant chemotherapy, and groups of patients who should not be offered chemotherapy," Ni...

Secrets of the sea yield stronger artificial bone

...ctor activates, prompting bone cells to invade the newly created pores. "Porosity will be created in situ to allow bone growth," says Tomsia. "When the polymer degrades, bone cells can proliferate into the porous ceramic scaffolding, allowing old bone to fuse with new bone. We provide the body with scaffo...

Study finds 60 new genes controlled by DNA snippet

...ated as exerting influence over a gene. Adding the newly confirmed segments to those already known, authors...t increase from the old definition. Of the genes newly found to be regulated by CArG-SRF, more than half encode for cytoskeletal or contractile proteins. P...

Newly discovered killer cell fights cancer

...ays Housseau. The blended cell turned out to be a newly identified actor on the immune system stage that retains all the molecular characteristics of both NK and dendritic cells. Probing further, Housseau scoured the surface of IKDCs to create a sketch of its molecular profile. He found that it produc...

Nano-particles effective in killing cancer with one-two punch of chemotherapeutics

...neering and Applied Science and a member of Penn's newly established Institute for Translational Medicine and Therapeutics. "Here we show that drug-delivering polymersomes will break down in the acidic environment of the cancer cells, allowing us to target these drugs within tumor cells." One key featu...

Scientists discover new genetic subtypes of common blood cancer

... genomic hybridization) to analyze samples from 67 newly diagnosed patients provided by Shaughnessy in Arkansas. The CGH technique compared the genomes of a normal blood cell with various myeloma cells in search of differences. The goal was to identify recurrent copy number alterations ?hotspots on the c...

Faults in newly discovered breast stem cells may lead to tumours

...rrent therapies. Under normal circumstances, the newly identified breast stem cell will produce healthy tissue. But it is believed that an accumulation of genetic errors, perhaps combined with external influences and a family predisposition, could cause the breast stem cell or a "daughter" cell to produc...

Liquid crystals show promise in controlling embryonic stem cells

... be killed in order to analyze the markers. "This newly devised cell culture system enables a new paradigm in stem cell research," says chemical and biological engineer and MRSEC Director Juan de Pablo. "Ultimately, we hope to use liquid crystalline materials to transmit desired sets of physical and chemi...

Bone and cartilage growth to blame for heart valve disease

...says principal investigator Nalini Rajamannan, MD, newly appointed director of the Center for Heart Valve Disease in the Bluhm Cardiovascular Institute of Northwestern Memorial Hospital and assistant professor of medicine, Northwestern University Feinberg School of Medicine, who examined diseased mitral an...

For the first time: Longevity modulated without disrupting life-sustaining function

...netics; since this signaling cascade including the newly identified protein is conserved across many species, including humans, these findings raise the prospect that one day it might be possible to medically tweak this pathway to slow aging and improve the quality of life without harmful consequences to t...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

... therapy and to the long-term success of HAART for newly infected people. By one estimate, about 50 percent of patients receiving antiretroviral therapy in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, people with an infection typically have a dive...

Computer simulation hints at new HIV drug target

... therapy and to the long-term success of HAART for newly infected people. By one estimate, about 50 percent of patients receiving antiretroviral therapy in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, people with an infection typically have a dive...

Viral 'fitness' explains different resistance patterns to aids drugs

...medications that were consumed, in turn, cause the newly resistant virus to become less fit. The type of medication also factors in. Differences in viral fitness of mutated resistant virus occur between different classes of antiretroviral drugs, said Bangsberg, who is an associate professor of medicine at...

Study shows that cells have a natural defense against HIV

... its RNA genetic material. The researchers exposed newly infected cells to the drugs and then measured changes in the amount of cDNA over time. These experiments showed that the cDNA was destroyed faster in cells with normal XPB and XPD compared to cells with mutant XPB or XPD. Cells with normal XPB prot...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...ave learned from years of population studies, with newly available technologies, developed with NIH support. These technologies reduced the cost of genotyping by more than 100-fold, making such a comprehensive effort affordable. Equally important, this effort will dramatically increase our understanding of...

New insights into neural tube defects

...ion the polarity of a cell is lost. Therefore, the newly formed daughter cells initially lack the information to direct them to migrate to the midline where they are needed for proper neural tube development. The report in Nature is the first to demonstrate that the polarity is restored to the daughter c...

Single microRNA causes cancer in transgenic mouse

...akes that happen. Still, the study suggests that a newly emerging class of artificially designed molecules (called antagomirs) may be able to block miR 155 expression and be an effective therapeutic strategy in patients with acute lymphoblastic leukemia or high grade lymphomas. ...

Thin tough skin, slow-growing gills protect larval Antarctic fish

...developing gills appear to be keys to survival for newly hatched Antarctic notothenioids, a group of fish whose adults thrive in icy waters because of antifreeze proteins (AFPs) in their blood. Such adaptations are important, researchers at the University of Illinois atUrbana-Champaign say, because the la...

Animal brains 'hard-wired' to recognize predator's foot movements, Queen's study suggests

...potential predator or prey is nearby. "Research on newly hatched chicks suggests that it works from very early on in an animal's development," says Dr. Troje. "It seems like their brains are 'hard wired' for this type of recognition." One impetus for starting this research several years ago was a questi...

Wrinkled membranes create novel drug-delivery system

...ng tissue. The solution, Chaieb said, might lie in newly discovered nanoparticles that can be chilled through magnetic cooling. Chaieb and colleagues at Illinois are exploring ways to coat the capsules with the nanoparticles. When exposed to a magnetic field, the nanoparticles would cool down and remove h...

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