30+ AIDS vaccine clinical trials in 24 countries, research occurring on every continent
...DS (UNAIDS) estimates that 4.3 million people were newly infected with HIV last year—bringing the total number of HIV-infected individuals to 40 million people worldwide. Explosive HIV epidemics also continue in Eastern Europe and Central Asia. Throughout the world, a preventive AIDS vaccine remains one of...Gut research yields new anti-cancer approach
...ments to confirm it. Study Details In the newly published study, researchers observed the effects of three compounds known from the literature to inhibit PPARgamma, T0070907, GW9662 and BADGE, on the ability of colorectal tumor cells to survive. High doses (10-100 ìM) of all three interfered with ...Human's ecological footprint in 2015 and Amazonia revealed
...he February issue of Frontiers, researchers review newly revealed changes in the Amazon rainforests and the ecosystem services they provide. The Amazon Basin is one of the world's most important bioregions, harboring rich array of plant and animal species and offering a wealth of goods and services to s...New compound prevents alcoholic behavior, relapse in animals by blocking stress response
A study of alcohol-dependent animals shows that a newly discovered compound that blocks chemical signals active during the brain’s response to stress effectively stops excessive drinking and prevents relapse. The new, synthetic compound, known as MTIP, also muted the anxiety that typically develops in r...Synthetic peptide targets latent papilloma virus infections
While a newly marketed vaccine promises to drastically reduce human papilloma virus (HPV) infections, the major cause of cervical cancer, a new discovery by University of California, Berkeley, researchers could some day help the millions of people already infected...A genetic 'gang of 4' drives spread of breast cancer
...r specific genes that propel metastasis. In the newly published experiments, the researchers also found that they could reduce the growth and spread of human breast tumors in mice by simultaneously targeting two of the proteins produced by these genes, using drugs already on the market. The researchers ...Research finds music training 'tunes' human auditory system
A newly published study by Northwestern University researchers suggests that Mom was right when she insisted that you continue music lessons -- even after it was clear that a professional music career was not in your future. The study, which will appear in ...Gene elevating breast cancer risk also causes prostate cancer
...vity. The next step was to set out to evaluate the newly detected PALB2 gene as a potential heritable breast cancer susceptibility candidate by screening for disease-related alterations. The results of this international research effort were recently published in Nature. The research first involved comp...Scientists discover new, readily available source of stem cells
...ound in the human body. The scientists believe the newly discovered stem cells, which they have named amniotic fluid-derived stem (AFS) cells, may represent an intermediate stage between embryonic stem cells and adult stem cells. They have markers consistent with both cell types. "It took this long to v...Technology reveals 'lock and key' proteins behind diseases
... version of the human proteins CFTR and MRP. These newly discovered protein interactors represent novel potential pharmaceutical targets. Through a series of biochemical and genetic tests, the researchers discovered that one of these interactors, Tus1p, regulates Ycf1p transporter function in a completely ...Early-stage sperm cells created from human bone marrow
...they did not develop further. Talking about his newly published research paper, Prof Nayernia, of Newcastle University, said : "We’re very excited about this discovery, particularly as our earlier work in mice suggests that we could develop this work even further. "Our next goal is to see if we can g...Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine
...r RPL8. Findings on the new cloning method and the newly identified tumor antigen will be published as a Priority Report in the April 15 issue of Cancer Research. The new antigen-cloning approach may allow scientists to design vaccines capable of directly stimulating helper T cells, aiding the developme...Wheat can fatally starve insect predators
A newly identified wheat gene produces proteins that appear to attack the stomach lining of a crop-destroying fly larvae so that the bugs starve to death. The gene's role in creating resistance to Hessian flies was a surprise to U.S. Department of Agricult...Ebola outbreaks killing thousands of gorillas and chimpanzees
...en ape social groups. The study provides hope that newly developed vaccines could control the devastating impact of Ebola on wild apes. Direct encounters between gorilla or chimpanzee social groups are rare. Therefore, when reports of large ape die-offs first surfaced in the late 1990s, outbreak amplific...New study may show how to forestall a fatal, virus-caused immune-system meltdown
...ilable now online, the scientists describe using a newly developed protein-scanning chip and a uniquely capable computer database to examine the activation and deactivation of more than a thousand proteins in cells from guinea pigs infected with two different strains of Pichinde virus. Guinea pigs infected...DNA ends: Common tool, different job
...llels between the conventional RPA complex and the newly discovered t-RPA complex. "Whereas the conventional RPA complex acts elsewhere in the genome to raise a red flag to attract the attention of the repair machinery," says Lundblad, "curiously, the t-RPA complex performs the exact opposite function ...Bats prey on nocturnally migrating songbirds
...rranean basin, such as the Iberian Peninsula. This newly recognized hazard adds to the numerous obstacles t...nt for fragile migratory passerines. Actually, the newly uncovered danger comes from the deep black sky, in the form of a 45 cm wing-spanned aerial-hawking m...Gene expression test reveals ER and HER-2 status of breast tumors
...ese tests to recommend treatment for patients with newly diagnosed stage I-III breast cancer. In the Lancet Oncology paper, they employed an Affymetrix microarray to gather estrogen receptor and HER-2 receptor gene expression data from 495 breast cancer samples from seven institutions. The samples incl...New cigarette designs don't offer lower predicted cancer risks
... out claims by tobacco companies that smoking such newly marketed "potentially reduced-exposure product" (PREP) cigarettes is safer. The study, appearing March 16 in the journal Cancer Epidemiology Biomarkers & Prevention, found that the predicted risks of lung cancer from PREP cigarettes is not meanin...New bird, bat species revealed by extensive DNA barcode studies
...organs in the body. But once it is there, like any newly stabilized species in different ecological niches, cancer is tough to get rid of. The former University of Alberta biologist has been working with DNA ?the molecule that carries our cells?genetic information ?ever since 1947, six years before its s...