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Tag: "newer" at biology news

Scientists re-engineer a well-known antibiotic to counter drug resistance

..., including vancomycin and teicoplanin (a somewhat newer drug similar to vancomycin). Both showed a significant increase in binding ability-roughly 40 times more potent than today's version of the drug. The actual re-engineering was extremely challenging, Boger said, requiring not only a detailed molecular...

Penicillin, amoxicillin: Step aside for strep throat treatment

...ly aren't doing the job and aren't as effective as newer antibiotics known as cephalosporins. In results pr...26 children showed that even a short course of the newer drugs is more effective than the traditional 10-day dose of the older antibiotics. Pediatricians at...

Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies

...hemselves and dangerously narrow the passageway. A newer generation of stents releases drugs to counteract this renarrowing process, called restenosis, but the polymer coatings that initially hold the drugs to the stents may stimulate inflammation. The inflammation in turn leads to restenosis. Researchers...

Emerging staph strains found to be increasingly deadly and deceptive

...But the situation can become more serious with the newer community-acquired strains, says Dr. DeLeo. "We do not know why cases of community-acquired MRSA infections are increasing, let alone how they flourish," he says. But scientists do know the community strains can cause more severe forms of disease. M...

DDT-resistant insects have additional genetic advantage that helps resistance spread

...nsecticide can unexpectedly increase resistance to newer compounds subsequently introduced to try and overc... therefore have pre-selected for resistance to the newer pyrethroids. ...

MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools

... methods: conventional "knockout" technology and a newer method in which the gene was "silenced." By showing what happened when the gene was disabled, the researchers determined the normal gene has two key functions: * DHR4 determines when metamorphosis should begin, when the fly should begin changin...

Scientists find a maturity gene in fly

... methods: conventional "knockout" technology and a newer method in which the gene was "silenced." By showing what happened when the gene was disabled, the researchers determined the normal gene has two key functions: * DHR4 determines when metamorphosis should begin, when the fly should begin changin...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...itiating a clinical trial in human PAH. Similarly, newer drugs that inhibit Survivin, currently in trials in oncology, might also be directly applicable to PAH patients, Dr. Michelakis explains. The researchers are supported by the Canadian Institutes of Health Research and Canada Research Chair Program, ...

Tamoxifen-like drug suggests new ways to selectively block estrogen

...owth and increasing the risk of uterine cancer. A newer group of drugs, known as selective estrogen receptor down-regulators, or SERDs, have a more potent anti-estrogen effect, involving destabilization of the estrogen receptor, which leads to its degradation. GW5638 fits somewhere in the middle, acting ...

Stealth Worms May Improve Insect Pest Control

...soil insects." The formulations keep improving as newer isolates of nematodes are found, and there is a lot of commercial interest in matching nematodes to pests, Stock says. "Yet these nematodes are so powerful and pathogenic not in and of themselves, but because they live in symbiosis with bacteria," S...

NJIT Presidential Award winner takes stem cell research another step

..., which is the use of allograft tissue, as well as newer treatments such as combining allograft with stem cells." One day soon, as a result of Arinzeh's research, patients could be treated with off-the-shelf stem-cell therapies instead of drugs. In five years, say, a patient with a bone ailment would visi...

Imaging Lymph Nodes with Nanoparticles

...arioustypes of imaging, ranging from ultrasound to newer technologies such asmagnetic resonance imaging (MRI). All these methods have problems; someare very invasive, others are very time consuming, and none arecompletely reliable.However in one of the more exciting crossovers from chemistry intomedicine, ...

Bioartificial kidney under study at MCG

...of the kidney. In ICUs today, doctors may opt for newer continuous dialysis therapies in which patients with renal failure receive dialysis around the clock. With more standard intermittent therapy, patients get several hours of dialysis three to four times a week. Since kidneys are constantly working, i...

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