UT Southwestern researchers find gene mutation that leads to 'broken hearts'
...ng animals and to detect cardiac defects that have never been described before", said Dr. Zhe Han, research instructor and co-first / co-senior author of this study. ...Drug discovery team to explore newly discovered deep-sea reefs
...ears that play important ecological roles, but has never before had the chance to explore this area. From ...ey goal is to find and collect organisms that have never been seen, which happens on almost every one of the Harbor Branch team's expeditions. Other organism...Rehydrate -- your RNA needs it
...hing similar had been seen in protein enzymes, but never before in RNA enzymes. The earlier finding, published in PNAS two years ago, suggested that information about changes in distant parts of the ribozyme travels through some sort of network to the core of the molecule, where chemical reactions take ...Montreal researchers identify defects of immune cells
...o be the leading cause of candidiasis, however, it never had been directly demonstrated. Now, they become designated targets for the development of novel treatments not only for candidiasis but other mucosal infections." "Secondary infections are the major cause of morbidity and mortality in people infec...Johns hopkins researchers find link between cell's energy use and genome health
...enetics at Hopkins and author of the study. "We've never seen anything that can turn off that many genes in a cell at once." The unexpected finding linking both gene usage and energy management machinery is "like finding out that an enzyme that breaks down food in the stomach also helps you remember tele...NASA technology helping injured US troops
...the stability to do squats and knee raises I could never do before." Physical therapists at Kindred Hospital of Greensboro, N.C., have discovered yet another use for the technology. "We use SAM with bariatric patients ?individuals who are remarkably overweight," said Mark Castleberry, Director of Rehabil...Adult stem cells are touchy-feely, need environmental clues
... environment might limit the fate of stem cells, I never really thought that it would be sufficient to direct cell fate," said Lee Sweeney, a coauthor of the study and chairman of Physiology in Penn's School of Medicine. "When I saw Adam's first images, I was stunned to see that the physical environment a...Healthy coral reefs of Madagascar resisting damage from climate change
...at's out there before we lose biodiversity that we never even knew existed." ...African parasite makes component of fat differently from all other organisms
...o get the myristate from its human host because we never could see any evidence that it could make the fatt...now we found that it uses a biochemical pathway we never knew to look for." They learned about this new fatty acid-making pathway by hunting the trypanosom...How plants avoid feeling the burn
...blem, Fisher had to attempt an experiment that had never been done before for any biomolecule: to control the charge of the biomolecule while measuring its ability to hold a current. By holding a carotenoid under potential control, Fisher could control whether the biomolecule was in a neutral state or in...First human study confirms that immune cells can be a primary cause of bone loss in gum disease
...ated presence of B and T lymphocytes. Since it has never been reported that any bacteria per se invade and resorb bone independent of osteoclast activation, RANKL expression by T cells and B cells proves to be one of the major stimuli of osteoclast precursor cells and, hence, bone loss through periodontal ...Newly identified protein complex sheds light on axon growth mechanism
...erised UNC-69, a previously known protein that had never been characterised. By studying mutants lacking unc-69 they show that the protein is widely expressed in the C.elegans nervous system and is required for normal axon development. Hengartner and colleagues then show that UNC-69 physically interacts w...A more powerful and efficient engine for rice: the C3-C4 challenge
...or the rice plant," Dr. Sheehy added. "But we have never really got under the hood and tried to improve the engine, or the photosynthetic efficiency, of the rice plant. It's going to be an enormously complex and difficult challenge, but we think that with all the new knowledge we have about the rice plant ...Malaria, potato famine pathogen share surprising trait
...oster. "These are very different pathogens, and we never realized that there might be some similarities between them." Kamoun says not to worry ?there's no chance that the potato pathogen will jump to humans, nor is it likely that the malaria parasite will start infecting plants. However, he said it's fe...Mice lacking key immune component still control chronic viral infections
...ase isn't known yet, but it's worth noting that we never would have even known to look for them if it weren't for our ability to study genetically altered mice," he says. ...Chocolate, wine, spicy foods may be OK for heartburn, Stanford study finds
...se for patients with milder heartburn symptoms who never walk into the doctor's office for advice." The cause of the conundrum lies in the nature of the studies that have been done. They generally looked at whether a particular food decreased the pressure exerted by the sphincter or increased the acidity ...UGA study explains peaks and troughs of dengue epidemics
...d wane over a period of several years, but they've never been quite sure why. With the incidence and range ...ing the factors that influence these epidemics has never been more important. A new study by researchers at the University of Georgia suggests that a brief...In a technical tour de force, Salk scientists take a global view of the epigenome
...tty dramatic. There are hundreds of genes that you never see expressed except in methylation mutants," says Ecker. Almost a third of Arabidopsis' ~ 26,000 genes were methylated in some manner, and where they were methylated determined the effect. As in mammals, methylation in regulatory regions next to ......tic as to what might be found," he said. "We would never have looked for this class of virus if it wasn't for the virus chip." Importantly, the researchers found that prostate cancers in which both copies of the RNASEL gene were crippled by mutation showed much more frequent XMRV infection than did those ...