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Tag: "neutralize" at biology news

Exploring the dark matter of the genome

...other functional elements, such as small RNAs that neutralize transposable elements, or transposons -- DNAs similar to viruses that hop around the genome and are capable of disrupting gene function. "Drosophila is ideal for studying genomics for many reasons, and especially for studying heterochromatin," sa...

New study suggests potential for a broadly-protective HIV vaccine

...ody to produce cross-reactive antibodies that will neutralize multiple viral strains. These results demonstrate ...body to produce cross-reactive antibodies that can neutralize multiple strains. USU Professors CAPT Gerald Quinnan, Jr., M.D., USPHS, and Christopher Broder, Ph.D...

A cherry on top: Tart cherries may alter heart/diabetes factors

... on which a higher reading means better ability to neutralize damaging free radical molecules produced in the body during metabolism. The rats that received cherries had higher antioxidant capacity, indicating lower oxidative stress in their bodies, than those that did not. In addition to blood measures, the...

Scientists unveil piece of HIV protein that may be key to AIDS vaccine development

... specific antibody, known as b12, that can broadly neutralize HIV. "Creating an HIV vaccine is one of the great scientific challenges of our time," says NIH Director Elias A. Zerhouni, M.D. "NIH researchers and their colleagues have revealed a gap in HIV's armor and have thereby opened a new avenue to meeting ...

Can engineered immune cells stop AIDS?

...help the immune system produce antibodies that can neutralize the virus," says Wang. "If we can design a modifie... and 2F5. Wang says these antibodies are known to neutralize the virus. "In laboratory tests, we remove harmful genes coding for the HIV virus and engineer t...

Chemicals in brown algae may protect against skin cancer

... when eaten, these compounds get to skin cells and neutralize the cancer-causing oxygen radicals that are produced by UV exposure." Laboratory research has shown that BAPs are strong antioxidants and may have anticancer properties. For this study, Stoner and his collaborators used a strain of hairless m...

Tiny Tampa Bay fish key to evolution of immune system

...te defensive system of its own, with features that neutralize what we're trying to do to it," Ostrov said. "For example, if we're trying to create a vaccine against a specific pathogen such as anthrax, smallpox or bird flu, we have to take into account the defensive measures those and other organisms might have...

New research identifies gene important for nicotine's effects on the brain

...tion of nerve cells, the better we will be able to neutralize its effects on behavior". Picciotto suggests that future research focus on signaling pathways inside nerve cells and understanding which pathways are really important for nicotine addiction as opposed to other types of abuse. Picciotto's research...

Experimental vaccine protects mice against deadly 1918 flu virus

...reated a technique for identifying antibodies that neutralize this virus, a tool that could help contain future pandemic flu strains. These findings are important, the researchers say, to understanding and preventing the recurrence of the H1N1 influenza virus that caused the 1918 pandemic and to protecting agai...

Pilot study successful in taming allergic reactions to food

... system’s production of antibodies that attack and neutralize allergens, Burks said. The seven subjects in t...this will further reduce their sensitivity or even neutralize the allergy altogether. The second study focuses on children who are allergic to peanuts, to see ...

What animals can tell us about hemorrhage, organ transplants and aging

... prevent reactive oxygen species (ROS) generation, neutralize them, or repair the damage it causes, would live the longest, the theory goes. Buffenstein's research with naked mole rats, the longest-lived rodent known, may cause physiologists to modify this theory. Metabolic rate. In theory, the higher the sp...

Analysis of breast-cancer gene role offers promising target

...mab (Herceptin) by adding a second drug seeking to neutralize the uPAR gene. "One major avenue of investigation would be to develop an antibody that prevents uPAR from binding to a molecule called uPA that can activate uPAR," Dr. Uhr said. ...

Orange, grapefruit juice for breakfast builds bones in rats

...or orange juice - mixed with sodium bicarbonate to neutralize acidity - was given to the rats each morning. "They drank it with no problem, every morning," Deyhim said. "They drank more fresh juice than I did during that period." Deyhim said the juice study was followed by a similar test with orange and grape...

Scientists discover why cornea is transparent and free of blood vessels, allowing vision

...od vessel growth) by acting as a "sink" to bind or neutralize the growth factors sent by the body to stimulate the growth of blood vessels. The cornea has long been known to have the remarkable and unusual property of not having blood vessels, but the exact reasons for this had remained unknown. These results...

U of M researchers discover genetic key to treating deadly fungal infections

...y researchers have discovered that C. albicans can neutralize an antifungal drug by modifying one of its own chromosomes. The cell duplicates one arm of chromosome 5 and deletes the other, replacing it with the duplicate arm. The altered chromosome is known as an "isochromosome." The effect of the duplication i...

Researchers find molecular 'brake' to cell death

...gh an accidental release, the nucleotide pool will neutralize the CC so that the cell can stay alive," he says. "So, in a way, it takes a large amount of CC to convince the cell that the damage is real, and that is what you see when cardiac cells die after a heart attack, for example." This finding has direct ...

Faults in newly discovered breast stem cells may lead to tumours

...d. Then a drug will be designed to engage with and neutralize the faulty feature of the stem cell. Further research is now under way on excised human breast tumours to confirm the findings derived from the mouse model. The research team is from the WEHI Group of the Victorian Breast Cancer Research Consortium...

Scientists force viruses to evolve as better delivery vehicles for gene therapy

...s are primed with antibodies to quickly tackle and neutralize it, thwarting any attempt at gene therapy. UC Ber...ly 1,000 times the level of antibodies required to neutralize the wild virus. By sequencing the survivor strains, the researchers discovered that the capsid prot...

High resolution 'snapshots' detail dynamics of a cocaine antibody

...bodies have shown some promise in their ability to neutralize cocaine toxicity, but their binding ability is sev...mmunopharmacotherapy has been proposed as a way to neutralize the drug outside the central nervous system- basically soaking up the drug before it has a chance to...

New cellular flaw found in some virulent breast cancers

...said Sicinski, it is difficult to design a drug to neutralize the action of a protein like cyclin D1. In the most recent experiments, the research team's objective was to determine precisely which of cyclin D1's several different functions was responsible for causing breast cancer. By creating laboratory mi...

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