VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum
...r absorption is significantly greater than that of neutral cisplatin, as well as other multi-nuclear platinum compounds. The enhanced uptake into cancer cells takes advantage of weak molecular interactions on the cells' surface. These results underscore the importance of the new compound's "non-covalent" int...How plants avoid feeling the burn
...her could control whether the biomolecule was in a neutral state or in the charged state (the oxidized state), while simultaneously measuring the electron transport through a single molecule. "The importance of this result is not only for understanding natural systems and photosynthesis, but also for the......aces or scenes. One oddball was simply a different neutral image, one was a different image that required the researchers to press a button, one was an emotional image, and one was a distinctly novel image. In fMRI, harmless radio signals and magnetic fields are used to measure blood flow in brain regions, w...Gene linked to rare disease activates fat breakdown
...mportant for fat breakdown, but its involvement in neutral lipid catabolism remained unexplained," Zechner said. "The discovery that CGI-58 acts as a very potent activator offers a new picture of how stored fat is broken down in adipose and other tissues." The finding solves a puzzle first raised in 2001 wi......ions of different types are detected in a crowd of neutral faces, researchers have demonstrated that male angry faces are a priority for visual processing ?particularly for male observers. The findings are reported by Mark Williams of the Massachusetts Institute of Technology and Jason Mattingley of the Univ...Mirrors in the mind: New studies elucidate how the brain reflects onto itself the actions of others
...etrated by one's self or by others) as essentially neutral in ownership. These findings inform our understanding of the motor system's role in social cognition, and support previous suggestions that the motor system may have strongly influenced developments in human social evolution. ...Climate change creates dramatic decline in red-winged black bird population
...ed. The North Atlantic Oscillation had returned to neutral values. "We found that the harem size [the number of female birds per male] had rebounded to 2.06 which is less than expected, but it did go up. We are currently measuring the length of the breeding season to see if that has changed, affecting the se...Pheromone from mother's milk may rapidly promote learning in newborn mammals
...neutral" odor and subsequently testing whether the neutral odor alone would later elicit the typical food-searching behavior in the pups, the researchers were able to show that the pheromone is indeed effective at promoting the ability of the newborns to learn the significance of new odors. The researchers s...Researchers identify neurons that assign value during learning
... a particular stimulus that would otherwise have a neutral influence on behavior. For example, if an animal s...tribute attractive or aversive values to so-called neutral stimuli, such as odors, in the course of associative learning? Past work had indicated that certa...New brain-chemistry differences found in depressed women
...ulties. They also had their brains imaged during a neutral emotional state. Just before the brain scans, the women also had their blood tested to measure levels of two hormones that are released in response to stress. The depressed women were then prescribed an antidepressant drug and reported regularly ...Huddling and a drop in metabolism allow penguins to survive the South Pole cold
...e emperor penguins during rest within their thermo neutral zone, of about 37.5°C to 38°C. This temperature range corresponds to the core temperature recorded at mid-pairing (from 37.1 to 38.1°C). A core temperature reduction during the pairing period to 36.5°C and a mean core temperature of 36.7°C (when aver...'The eyes have it' -- Autism research yields surprising results
...the eyes and mouth were either ‘freeze-framed?in a neutral expression, or animated and expressive. By showing a sequence of different combinations, they were able to gauge which aspects of the face were used by the autistic children to ‘read?someone’s mental state ?and how successful they were. In the sec...Coated nanoparticles solve sticky drug-delivery problem
...s that were attracted to water, and they had a net neutral electrical charge," said Samuel K. Lai, a Johns Hopkins chemical and biomolecular engineering doctoral student from Canada and Hong Kong who was lead author of the journal article. "We thought that if we could coat a drug-delivery nanoparticle with a......ful things. Distracting information is refused and neutral information may enter. In the event of tiredness, ...as got nothing to do with mango and is therefore a neutral word. Quicker The test revealed that the study subjects remembered distracting words less w......ful things. Distracting information is refused and neutral information may enter. In the event of tiredness, ...as got nothing to do with mango and is therefore a neutral word. Quicker The test revealed that the study subjects remembered distracting words less w...'Juiced-up' battery fueled by sugar could power small portable electronics
...ful things. Distracting information is refused and neutral information may enter. In the event of tiredness, ...as got nothing to do with mango and is therefore a neutral word. Quicker The test revealed that the study subjects remembered distracting words less w...Mine runoff continues to provide clues to microbial diversification
...rganisms to survive. A pH level of 7 is considered neutral and most proteins prefer pH levels between 5 and 7. In addition, the water from the mine often exceeds 120 degrees Fahrenheit. Because of their simpler makeup, the Banfield Laboratory established these communities as a model system in the mid-1990s. ...Traumas like Sept. 11 make brains more reactive to fear
...s to activate the amygdalae relative to looking at neutral faces," said Ganzel. "So we were looking to see if people who have had a very bad experience would have more response to this relatively mild everyday stimulus." Indeed, the amygdalae of those who were close to the twin towers were significantly mo...A frown or a smile? Children with autism can't discern
...eries of faces depicting angry, fearful, happy and neutral expressions. In half the faces, the eyes were averted; with the other half, the faces stared back at the children. With the typically developing group, the researchers found significant differences in activity in a part of the brain called the ven...... an alpha-helix. Under normal tissue conditions of neutral pH, the water-soluble form is favored. At acidic pH, the transmembrane alpha-helix predominates. An earlier paper from the same groups shows that at low pH, pHLIP can move cell-impermeable molecules across a cell membrane, where they are released...