New mechanism underlying pain found
...overed a new molecular mechanism that may underlie neuropathic pain. The clearer understanding of the root-cause of chronic neuropathic pain, and the preclinical validation of new targets for pharmaceutical therapies shown in this resea...Novel method reveals how menthol discovery could point towards new or improved pain therapies
...nsidered targets to treat chronic inflammatory and neuropathic pain indications. Understanding how small molecules such as menthol affect the function of these proteins could be crucial in designing future drugs that can either activate or block them." The study was released in an advanced online version by th...Master genetic switch found for chronic pain
...cally expressed in pain-receptor cells involved in neuropathic pain. When they knocked out the gene, they found that the normal development of such specialized nerve cells was impaired. The animals had lost ion channels known to be involved in reacting to painful heat or cold, as well as those involved in pain d...Scientists use gene transfer technology and common virus to block neuropathic pain
...irtually nothing you can do about it. It's called neuropathic pain, and it's a common complication of many disea...veloped a way to block the signals responsible for neuropathic pain. The secret to their success is based on a virus called herpes simplex or HSV ?the same virus t...Scientists use gene transfer technology and common virus to block neuropathic pain in animals
... you can do about it. David Fink, M.D.It's called neuropathic pain, and it's a common complication of many disea...veloped a way to block the signals responsible for neuropathic pain. The secret to their success is based on a virus called herpes simplex or HSV ?the same virus t...Molecular miners find pain relief drugs from the sea
...males, and later its effectiveness in treating the neuropathic pain associated with diabetes. From the Universit... human pain syndromes, including post-surgical and neuropathic pain," Associate Professor Livett says. "In addition, it has the unique property that it appears to...Scripps research scientists identify infertility molecule
...ew neurons -- in mice, and can also participate in neuropathic pain models. Wanting to go further, they created what is known as a knock-out mouse model for a specific LPA receptor. These are special mice that lack one or more particular genes of interest -- in this case, a gene that encodes a particular LPA re......adjunctive treatment for the symptomatic relief of neuropathic pain in adults with multiple sclerosis (MS). Canad...d for additional treatment options in the field of neuropathic pain in MS.?/p> Neuropathic pain Pain is a common symptom of MS occurring in up to 86 per cent o...