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Tag: "neurofibromatosis" at biology news

Mouse brain tumors mimic those in human genetic disorder

...odel of braintumors common in the genetic disorder neurofibromatosis 1 (NF1)successfully mimics the human condition and...rry A, Hernandez MR, Gutmann DH. Naturalhistory of neurofibromatosis 1-associated optic nerve glioma formationin mice. Annals of Neurology, January 2005....

Potential treatments for neurofibromatosis

... and allergic reactions. Mast cells play a role in neurofibromatosis because they also are involved in blood vessel for...alled NF 1. In humans, NF 1 mutations resulting in neurofibromatosis occur in one in 4,000 births, equally affecting both sexes and all races and ethnicities. It is the ...

Anti-cancer drugs may hold promise for premature aging disorder

...ntly being tested in people with myeloid leukemia, neurofibromatosis and other conditions, might also provide a potential therapy for children suffering from Hutchinson-Gilford Progeria Syndrome, commonly referred to as progeria. A related study from Stephen Young, M.D., and colleagues at the University of California ...

Recreating 'Flowers for Algernon' with a happy ending

...tudied in mice bred to develop the disease, called neurofibromatosis 1 (NF1). The results proved so hopeful, that the Food and Drug Administration approved the use of the drugs in three clinical trials currently under review to test the effect of statins in children and adults born with NF1. The findings could hel...

Genetic fingerprints identify brain tumors' origins

... Approximately 15 percent of all PAs are linked to neurofibromatosis 1 (NF1), a genetic condition that causes childhood brain tumors and is a primary focus of Gutmann's research. However, the genetic basis for the majority of PAs is unexplained. In the new study, Gutmann led six laboratories in the most detailed ge...

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