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Tag: "neural" at biology news

Wisconsin scientists grow critical nerve cells

...believes, may be that they are one of the earliest neural structures to emerge in a developing embryo. With ...ise timing. To start, the Wisconsin team generated neural stem cells from the embryonic stem cells. They then transformed the neural cells into progenitor cel...

Neuronal 'traffic jam' marks early Alzheimer's disease

...t produced Alzheimer's-like plaques and subsequent neural degeneration. The scientists' analyses of the neurons in those mice revealed clear defects, said Goldstein. "What we saw quite early in the life of those animals -- well before any plaque deposition -- were obvious axonal defects," said Goldstein. "...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...h signaling is known to beimportant in a number of neural cell fate determination anddevelopmental processes, and is conserved in species from human toroundworm. In all processes in which it participates, Notch signalingshows the ability to sense a small change in cell fate and amplify it,acting as a sort o...

Research on Worms Yields Clues on Aging

... affect aging partly throughtheir influence on the neural system involved in the insulin signalingpathway and partly through an independent mechanism, according toKornfeld."Our experiments show there is an important connection between neuralfunction and longevity," Kornfeld says. "We're continuing this line...

Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

...um offers powerful feature detection, committeesof neural networks, committees of SVMs and committees of Bayesianclassifiers that are more suitable to the intermediate or advancedresearcher."This new release illustrates our commitment to supporting andadvancing the GeneLinker products. The feature sets in e...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...),which previous research suggests plays a role in neural development,"says Reinisch. "Fluctuations in PKA m...ns of this enzyme may affect neuraldevelopment and neural connections by activating or inactivating otherproteins.Demonstrating that clam embryos are affected...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

...),which previous research suggests plays a role in neural development,"says Reinisch. "Fluctuations in PKA m...ns of this enzyme may affect neuraldevelopment and neural connections by activating or inactivating otherproteins.Demonstrating that clam embryos are affected...

New research questions basic tenet of neuron function

...s thought to play a role in the development of the neural circuitry in the brain and body, while activity-dependent release is responsible for functions such as learning and memory. ...

Vital step in cellular migration described by UCSD medical researchers

...oted that alpha4 integrins are widely expressed in neural crest cells, immune system leukocytes (such as T cells), striated and smooth muscle, and neurons. For this reason, they believe the mechanism used by alpha4 integrins to localize Rac activity may participate in a wide variety of cell migratory and pa...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...troduction can provide insight into how to protect neural cells. This is showing us a new way to approach the problem.?/p> Parkinson's disease is caused by the death of brain cells that produce a vital chemical known as dopamine, which carries messages that tell the body how and when to move. In tests w...

New insight into people who 'see' colors in letters and numbers

...p, they theorize, by a failure of the "pruning" of neural connections between the areas in the developing br... are using the condition to gain insights into the neural basis of perception. In their experiments with synesthetes who report seeing colors when they view ...

Bird Brains Show How Trial and Error May Contribute to Learning

...yzed the relationship between song and the natural neural activity of LMAN during the two types of male finch song, the performance-quality song directed at females, accompanied by some posturing and feather plumping, and the experimental solo variations, called "undirected," akin to singing in the shower. ...

Key Trigger Of Opioid Withdrawal Symptoms Found

...tworks of neurons in the brain is the basis of all neural activity. Transporter molecules are the proteins that retrieve neurotransmitter molecules from the spaces between neurons after they trigger nerve impulse, to reload the neuron for its next signaling burst. Bagley and her colleagues also discovered ...

Gene therapy for Parkinson's disease moves forward in animals

...troduction can provide insight into how to protect neural cells. This is showing us a new way to approach the problem." Parkinson's disease is caused by the death of brain cells that produce a vital chemical known as dopamine, which carries messages that tell the body how and when to move. In tests with 31...

Stem cells from brain transformed to produce insulin at Stanford

... transplanted into humans. Kim thought that human neural stem cells may be one way to sidestep the more pro...aken together, this evidence suggested to Kim that neural stem cells may be able to produce insulin. Despite Kim's informed hunch, the fact that it worked is...

UCSD-Salk Team Show Protein’s Gene-Silencing Role In Development of Nervous System

.... The phosphatases are required for maintenance of neural stem cells and for silencing expression of neuronal genes in non-nervous system tissues. Published in the January 28, 2005 issue of the journal Science, the study found that the phosphatases, called small carboxyl-terminal domain phosphatases (SCPs)...

Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive

...we found several brain areas where the strength of neural activity changed with the length of the romance. E...It may be produced, instead, by a constellation of neural systems that converge onto widespread regions of the caudate where there is a flexible combinatorial...

Brain-mapping technique aids understanding of sleep, wakefulness

...and his research group new hope for navigating the neural network. The technique involves genetically engin...o apply the technique in order to study a specific neural pathway. They introduced the tracer into mice so that it was expressed only in orexin neurons, which...

Brain Scans Reveal How Gene May Boost Schizophrenia Risk

...standing of schizophrenia because it clarifies the neural mechanism for a well-established risk gene." Also participating in the NIMH brain imaging study were: Dr. Daniel Weinberger, Philip Kohn, Dr. Bhaskar Kolachana, Shane Kippenhan, NIMH; Dr. Aideen McInerney-Leo, Dr. Robert Nussbaum, National Human Gen...

Cerebral navigation: How do nerve fibers know what direction to grow in?

... mice had abnormal axon projections and defects in neural circuitry formation. The second paper demonstrates the role of a protein called ephexin1 in axon guidance. By itself, ephexin 1 promotes axon growth; neurons from mice genetically modified to lack ephexin1 had significantly shorter axons. But when e...

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