Tag: "neglected" at biology news

Finding Cures For Tropical Diseases: Is Open Source An Answer?

..."open source" approach todiscovering new drugs for neglected diseases.They call their approach the Tropical Diseases Initiative(www.tropicaldisease.org), or TDI. "We envisage TDI as a decentralized,Web-based, community-wide effort where scientists from laboratories,universities, institutes, and corporations ca...

Study reveals dramatic difference between breast cancers in US and Africa

...of one year. That should give you some idea of how neglected this continent is by cancer researchers." The Breast Cancer Research Foundation and the National Women's Cancer Research Alliance funded the study, which was presented April 18, 2005, at the 96th annual meeting of the American Association for Cancer...

A new way to share models of biological systems

...erently than the real organism, we know that we've neglected an important component of the system. Quantitative models can also reveal previously unappreciated properties of complex systems, paving the way towards new drug treatments. This approach, known as 'computational systems biology,' is becoming increas...

Compound might defeat African sleeping sickness, clinical trial beginning this month

...discover and develop drugs for poorer countries or neglected diseases, Tidwell said. "We have been able to red...did in Africa inspired Olson to work on deadly but neglected illnesses, she said. "What goes 'round, comes 'round," Olson said. "We have a real opportunity with...

Fragment of yellow fever virus may hold key to safer vaccine

...ns in northern Europe. "Yellow fever research was neglected because the vaccine was so effective," ter Meulen said. "Medical science works in cycles. As soon as the problem is solved, the caravan moves on. Once the disease comes back, people realize they are lacking certain information." To learn more about ...

A New Era Of Hope For Neglected Diseases

...period when very few therapies were introduced for neglected diseases, which kill around 3m people a year and c...o delivering safe, effective, affordable drugs for neglected diseases. In a linked editorial, entitled "A New Era of Hope for the World's Most Neglected Disease...

A New Era of Hope for the World's Most Neglected Diseases

...ve designated a group of 13 tropical infections as neglected diseases (Kala-azar (leishmaniasis), African Sleep.... Hence, only 13 new drugs have been developed for neglected tropical diseases since 1975, and they have garnered little international attention compared with “t...

Teasing out tissue from blood

...ollege London says most stem cell researchers have neglected the idea of de-differentiating adult cells in favour of using embryonic stem cells. However, he warned there could be problems with using adult cells,because they have suffered years of genetic damage. "With embryonic cells, they're fresh, and not co...

DNA to the defense

... for research into new control strategies for this neglected disease. The current study underscores this parasite's reputation as a master of adaptation, devoting unprecedented resources to avoiding immune attack. Since the VSG coat appears to prevent access to other non-variable parasite proteins, such capa...

Public Library of Science to launch new, open access journal on neglected tropical diseases

...st open access journal devoted to the world's most neglected diseases. PLoS Neglected Tropical Diseases ( www...l discuss the journal during a panel discussion on neglected diseases on September 21 at the Clinton Global Initiative's annual meeting in New York. The panel w...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

...their own expertise and capacity. "Though largely neglected by the field of regenerative medicine to date, we suggest that developing countries could potentially benefit from advances in regenerative medicine to address the epidemic of non-communicable disease and other pressing health needs," the authors say...

Increase in drug development for killer diseases is not enough

...Group, The George Institute, argues that drugs for neglected diseases are increasingly being developed partly d...ill be discussing the rise of drug development for neglected diseases and the role of PPPs at a major international conference, organised by the ESRC Innogen Cen...

Biologists call for better choice of model organisms in 'evo-devo'

...ect new models specifically to illuminate hitherto neglected general themes within evo-devo.". In other cases, new model organisms are chosen on the basis of how well they are thought to represent a particular ancestral organism. In connection to this practice, the researchers point to ‘basal bias?as anothe...

Inhibiting blood to save the brain

...Experimental Medicine. "Blood proteins have been neglected as a therapeutic target, but this research shows that a blood clotting factor is an important player in MS." MS is an inflammatory disease that affects the central nervous system, causing symptoms such as loss of balance and muscle coordination...

Tracing broken wiring in stroke patients

... more impaired the patients were in perceiving the neglected region of their visual field, said the researchers. Such findings, they commented, show that "FC MRI is a promising new tool for the investigation of brain-behavior relationships in patient populations. It makes no demands on the subject other tha...

Potent possibilities for parasite attack

...imited resources." Leishmaniasis is one of the neglected diseases that desperately need new research, as WHO/TDR notes: "Treatment of visceral leishmanisis by first-line drugs is long (4 weeks), given systemically, and expensive (US$120–150)". The affordable drugs have been in use for more than half a cent...

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