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Tag: "negative" at biology news

Enzyme delivered in smaller package protects cells from radiation damage

...at such high doses of radiation may have long-term negative effects on healthy tissues and organs, such as the kidney, liver and thyroid gland. Based on previous studies showing that intravenous gene therapy delivery of the enzyme manganese superoxide dismutase (MnSOD) could protect mice from whole body i...

Brain inflammation may be friend, not foe, for Alzheimer's patients

... of evidence that inflammation plays a potentially negative role in Alzheimer’s disease,” said O’Banion. “But much of the evidence comes from experiments with cells in a dish or postmortem human tissue, not from living organisms in which disease progression is closely monitored. “People have talked for a l...

ASU research shows connection between testosterone, dietary antioxidants and bird coloration

...n originally thought. They appear to fight off the negative impacts that testosterone can have on an animal’s health. The researchers, Kevin McGraw an assistant professor in ASU’s School of Life Sciences and Daniel Ardia, of Franklin and Marshall College in Pennsylvania, focused their work on zebra finche...

Mutating the entire genome

...en gene in a designed manner,” Capecchi says. “The negative side is, it takes work and money to do that.” The new method is “a cheaper way of knocking out a gene as well as regulatory sequences.” Capecchi says it now costs about $10,000 to genetically engineer a mouse with a particular gene or other DNA s...

Putting feelings into words produces therapeutic effects in the brain

...ople don’t do this to intentionally overcome their negative feelings; it just seems to have that effect. Popul...a alarm center response in the brain that triggers negative feelings. Creswell, who conducted the mindfulness research as an advanced graduate student of psy...

A frown or a smile? Children with autism can't discern

...ressions, the brain may quiet down, because when a negative gaze is averted, it is no longer seen as a direct threat. “Gaze has a huge impact on our brains because it conveys part of the meaning of that expression to the individual. It cues the individual to what is significant,?Davies said. While the re...

New bacteria test could improve quality of fruit and vegetable juice

...ng methods are utilized, some of which yield false negative results. This has complicated international trade. Japan, along with other developed countries, has a zero tolerance for this bacterium in imported juices, Lin said. He said identification is a challenge because spoilage can be diffi...

Heavy multivitamin use may be linked to advanced prostate cancer

...sity Hospital in Denmark, discuss the positive and negative health effects of antioxidant supplements. “Lawson [and colleagues] add to the growing evidence that questions the beneficial value of antioxidant vitamin pills in generally well-nourished populations and underscore the possibility that antioxidant s...

Executable biology -- Computer science sheds light on animal development

...e of two cellular signaling pathways, as well as a negative feedback loop that had not been described before. These kinds of models hold great promise for future exploration of a variety of biological systems, explains lead EPFL researcher and biologist Dr. Jasmin Fisher. "Once a robust model has been bui...

Researchers find link between food odors and lifespan in fruit flies

...?in fruit flies, just the smell of food can have a negative effect on longevity. Scientists have known for de...?in fruit flies, just the smell of food can have a negative effect on longevity. Scientists have known for decades that restricted dietary intake can increas...

Scientists identify pancreatic cancer stem cells

...d. The difference is in one marker, CD24, which is negative in breast cancer and positive in pancreatic cancer, according to Simeone. "These studies suggest that several stem cell markers may be shared by cancer stem cells in different tumor types, such as CD44 and CD133, but it is possible that each tumo...

Risk of HIV transmission highest early in infection

...cted may not know it, and will probably often test negative by conventional antibody screening. Hence, we must do a much better job of identifying recently infected people if we are to be able to counsel them to modify high-risk sexual behavior and desist from transmitting the virus.? He suggested the deve...

Transfusion expert urges wider use of filtered blood

...lls from transfused blood reduces the chances of a negative reaction by the host immune system. In 1998 the University's Strong Memorial Hospital was among the first hospitals in the country to begin using leukoreduced blood for all cardiac surgery cases. Since then, the hospital has extended its leukoreducti...

In obesity, brain becomes 'unaware' of fat

... “Previous studies have suggested that SOCS-3 is a negative regulator of leptin,?Cowley said. “As animals become bigger and fatter and leptin increases, SOCS-3 may rise to decrease the signal. It seems that in obesity, SOCS-3 might end up overriding the [leptin] signal completely.? When the amount of fat in...

Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising

...e deep penetration of jets into the skin, creating negative reactions of nerves and capillaries. The pulsed mircrojets engineered by the researchers combine high velocity (more than 100 meters per second) with very small jet diameters (between 50 and 100 micrometers), delivering only 2 to 15 nanoliters of li...

Fascinating spider silk

...n the protein are deprotonated, which gives them a negative charge. This charge weakens the interactions between the hydrophobic, lipophilic regions of the proteins, which are necessary for oligomerization. "Our insights form a foundation for the establishment of an effective spinning process for the produ...

Scripps research study shows humans and plants share common regulatory pathway

..."In this hypothesis, the target protein would be a negative regulator of immune responses." Future studies, Ulevitch said, will focus on the extensive literature that exists describing the R protein dependent immunity in plants to better understand human NLR pathways, especially those dependent on Nod1. ...

Tropical forests -- Earth's air conditioner

...e deforestation, and accounts for the positive and negative climate effects of tree cover at different latitudes. The result, which appears in this week’s early online edition of the Proceedings of the National Academy of Sciences, makes a strong case for protecting and restoring tropical forests. "Tropica...

The penalty of having a sister -- why sibling sex matters for male saiga antelopes

...ase in birth weight is likely to have an amplified negative effect on male reproductive fitness in species where competition amongst males for mates is very high." The saiga antelope provides scientists with an ideal opportunity to investigate the effects of mixed-sex twin litters on size and development, ...

Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell

...ical processes, and--when perturbed--can result in negative outcomes such as tumor formation. Understanding how live cells function is therefore invaluable for molecular and cellular biologists, and advanced techniques to visualize cells in action are of great importance. The current issue of Cold Spring Har...

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