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Tag: "needed" at biology news

Discovery of T-cell 'traffic control' boosts new drug promise

...ate into the blood and onto tissues where they are needed to fight infection. In a key experiment, Goetzl's and Rosen's labs showed that by chemically displacing S1P, its natural braking effect is released, stimulating T cell traffic into lymph nodes. Because this also blocks S1P's chemotactic influence, m...

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

...between women and men. Cultural programs are also needed for reshaping gender roles, such as educating more women about safe-sex practices, use of condoms, lessons on negotiating safe sex, and awareness campaigns about where to seek testing and treatment. Quinn says that women are different when it comes ...

'Sinkers' provide missing piece in deep-sea puzzle

...might be delivering to the seafloor, Robison first needed to find out how common they were. For ten years (f...ime. To complete their study, the scientists also needed to know how much carbon each sinker transported to the seafloor. But first they had to collect some ...

Molecular miners find pain relief drugs from the sea

...Pharmaceuticals to synthesise gram amounts of ACV1 needed for the planned human clinical trials for diabetic neuropathy. "With an increasing age demographic in our society the need for more effective pain suppressing compounds is a priority. ACV1 may fill this unmet need," Associate Professor Livett says. ...

Microbe has huge role in ocean life, carbon cycle

...1 recycle organic carbon - producing the nutrients needed for algal growth. "Ultimately, SAR11 through its sheer abundance plays a major role in the Earth's carbon cycle," Giovannoni said. "Quite simply, this is something we need to know more about. SAR11 is a major consumer of the organic carbon in the oc...

York scientists warn of dramatic impact of climate change on Africa

...of plants to climate change. Dr Lovett added: "We needed a method that would help fill in gaps in knowledge. The technique we used is called a genetic algorithm because it works in a similar way to the effect of evolution on chromosomes ?the programme combines different variables in lots of different ways ...

AACR Favors 'full spectrum of stem cell research biology'

...sed only as precursors to the differentiated cells needed to replenish damaged tissue. In light of the recent cloning of patient-specific human embryonic stem cells by researchers in South Korea, AACR Science Policy and Legislative Affairs Committee Chairman William G. Nelson V, M.D., Ph.D., pointed to the...

UIC developing drug for SARS

...tion of a long chain of proteins, all of which are needed for the virus to propagate. Two enzymes, or protea...hain to release the individual proteins, the parts needed to assemble a mature virus. These two proteases -- called 3CLpro and PLpro -- are UIC's targets for...

Opiates Better Than Sedatives For Treating Newborns In Withdrawal

...y reduce withdrawal severity, but more research is needed using a higher initial dose of opiate, and to examine the effects of phenobarbitone on infant development. In the 1999 U.S. National Household Survey on Drug Abuse, 3.4 percent of pregnant women reported illicit drug use in the past month, which acc...

Researchers discover new route to hemoglobin synthesis

...y reduce withdrawal severity, but more research is needed using a higher initial dose of opiate, and to examine the effects of phenobarbitone on infant development. In the 1999 U.S. National Household Survey on Drug Abuse, 3.4 percent of pregnant women reported illicit drug use in the past month, which acc...

Hospitalizations because of chicken pox down dramatically since implementation of vaccine

...s ago. However, nationally representative data are needed to more accurately monitor the impact of the varicella vaccination program. The Council of State and Territorial Epidemiologists has recommended that states now begin to conduct case-based surveillance," the authors conclude. (JAMA. 2005; 294:797?02...

Breakthrough in micro-device fabrication combines biology and synthetic chemistry

...om microshells do not have the specific properties needed for device applications, such as electrical conductivity, biocompatibility, thermal stability, and chemical compatibility. According to the study's lead author, Kenneth Sandhage, "By demonstrating that biologically derived structures can be chemical...

From a Few Wild Ancestors, a Citrus Cornucopia

...issue containing the essential genetic information needed to start new citrus plants. The citrus genebank -... were redundancies and gaps in the collection that needed to be sorted out,?says Krueger, “and some specimens had even been mislabeled.?Mistakes are costly fo...

Stem cells bring fast direct improvement, without differentiation, in acute renal failure

... novel therapeutic interventions that are urgently needed to treat this common, devastating and costly human...e seen in these experiments, long-term studies are needed to prove that no adverse effects occur after in vivo administration of adult MSC. * Also to be ...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...tive chain reaction that follows. In essence, they needed a way to plug up the receptor and found such a device in a gene encoding the IL-1 receptor antagonist, or IL-1 Ra. Because it was the first trial of its kind and safety was a key concern, the protocol was designed so that the gene would be delivered...

Genomics researchers discover protein deficit that causes drug toxicity

...cids -- that results in the absence of the protein needed to properly metabolize thiopurine drugs. In patients with the genetic defect, instead of helping heal, a standard dose of thiopurine drugs can cause fatal bone marrow destruction. Though Mayo Clinic researchers described this genetically variable res...

Genes linked to treatment resistance in children with leukemia

... the future, a simple blood test may be all that's needed to make that determination. "This research showcases a new direction for cancer treatment ?personalized chemotherapy based on the genetics of the patient," said Mary Relling, Pharm.D., St. Jude faculty member and lead study author. "In our study, se...

Single gene is genetic switch for fly sexual behavior

...ion, and licking, but a single gene is all that is needed to produce this complex behavior, according to new research published in this week's issue of the journal Cell. The gene encodes the Fruitless protein. Male and female flies carry different versions of the fruitless protein, as a result of sex-speci...

Molecular mechanism of feather formation found

...o ongoing down-regulation of normal Shh expression needed to form the barbs. Harris and colleagues used a similar experiment to test whether Shh could up-regulate its own expression during barb formation, and found that it could. Similarly, they found that regional expression of Shh led to detectable up-re...

Learning how SARS spikes its quarry

...ese findings give us the beginnings of information needed -- if a new virus were isolated -- to make predictive guesses about infectivity, so that we can better give advance warning." He also noted that laboratory studies indicate that the fragment of the spike protein they used could provide the basis of...

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