New tool reveals secrets of migrating cells
...ht up. A certain energy or color of laser light is needed to make the dye, in this case green fluorescent pr... two photons of light, each photon half the energy needed to excite it, the dye can absorb them together and then fluoresce. The less energetic, long-waveleng...Decisions, decisions: Male or female?
...ide whether to eventually become the sperm or eggs needed later for adult reproduction," said Mark Van Doren...germ cells are one of the most ancient cell types, needed by every type of animal to reproduce," Van Doren said. "Their developmental program is very similar,...Study: Harmless virus kills some cancers
...said. "Although we suspect it is, more studies are needed to determine if the mechanism through which AAV2 destroys cancer cells is the same." Scientists often refer to cancer cells as deregulated, meaning they are no longer acting or communicating like normal, healthy cells. It appears that AAV2 is able t...The genetic origins of corn on the cob
...sa1. But we suspect that as the ear got larger, it needed special alleles of ramosa1 to prevent the extra rows from forming branches instead of kernels," says Martienssen. "There may have been other reasons for selecting an unbranched ear, including the interaction with other genes that were subsequently lo...$6.5 Million Grant for Microarray Center at Yale School of Medicine
...sa1. But we suspect that as the ear got larger, it needed special alleles of ramosa1 to prevent the extra rows from forming branches instead of kernels," says Martienssen. "There may have been other reasons for selecting an unbranched ear, including the interaction with other genes that were subsequently lo...New vaccine protects more effectively against tuberculosis
...is in adults. A more efficient vaccine is urgently needed for control of this global threat. Recombinant BCG, which express listeriolysin and is deleted for the urease gene, has been created and shown to stimulate far more efficacious protection against tuberculosis than the BCG vaccine currently in use. ...Drug Offers Alternative to Surgical Treatment After Miscarriage
...spiration group experienced treatment failure, and needed to undergo the procedure a second time. Complicati...cent said they would choose the drug again if they needed to, and 83 percent said they would recommend it to other women. Dr. Zhang noted that, because misop...Scientists discover that three molecules may be developed into new Alzheimer's drugs
... that several different medications will likely be needed to control it, said Kosik. The same is true for many other diseases –?from AIDS to cancer. "It is likely that we will need to strategically target different aspects of the disease and put them together." Kosik and his team chose to focus on the neur...Sleeping Sickness Epidemic Spreading in Uganda
...spiration group experienced treatment failure, and needed to undergo the procedure a second time. Complicati...cent said they would choose the drug again if they needed to, and 83 percent said they would recommend it to other women. Dr. Zhang noted that, because misop...Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
... that several different medications will likely be needed to control it, said Kosik. The same is true for many other diseases –?from AIDS to cancer. "It is likely that we will need to strategically target different aspects of the disease and put them together." Kosik and his team chose to focus on the neur...Improving the potential of cancer vaccines
...ntibody. "But you may also deplete the good cells needed for fighting cancer," said Wang. He and his group identified particular ligands (a special stretch of guanosine-containing DNA material) that can bind specifically to a particular receptor called human Toll-like receptor 8 and then turn off the supp...New protein vital for immune response is found in surprise location
...at MAVS binds with RIG-I, but more experiments are needed to determine just how MAVS functions within the cell. Other UT Southwestern researchers involved in the studies were lead authors Rashu Seth, a graduate student research assistant, and Dr. Lijun Sun, a postdoctoral researcher in molecular biology, a...Why are coyotes getting more aggressive?
...arted foraging in suburban areas, more research is needed to find out why and how to prevent potential conflicts with people. Curtis and his colleagues are launching a five-year study of coyote ecology and behavior in urban and suburban areas of New York state, thanks to a grant of $428,000 from the New Yo...Gene expands malaria's invasion options
...alic acid-independent parasites than in those that needed the sugar for cell entry. These results suggested that activation of the PfRh4 gene was required for the parasite to make the switch to sialic acid-independent invasion. Indeed, the team was able to find PfRh4 protein in sialic acid-independent ...OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies
... The scientists also caution that more research is needed in regard to determining the appropriate vitamin C dosage for humans. Finally, studies need to be conducted to demonstrate that giving pregnant women higher levels of vitamin C will not itself cause development problems. The ONPRC is a registered re...USC researchers determine mechanism of action of chemotherapy drug
...of cancer cells via disruption of critical enzymes needed for cell survival and replication. "We have increased the understanding of this drug's mechanism of action," Hacia said of the study, adding that it also may "provide support for the hypothesis that agents that disrupt metabolism and increase intrac...New type of rejection blocker protects kidneys after transplant
...s. More than half of cyclosporine treated patients needed anti-hypertensive medication compared to one-third of patients in the two belatacept groups. Over the past 20 years, drugs like cyclosporine (a calcineurin inhibitor) and prednisone (a corticosteroid) have been highly successful in overcoming organ...Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades
...gradation. Proper land use management policies are needed to protecting existing vegetative cover from overgrazing, over-exploitation, trampling and unsustainable irrigation practices. Finally, creating viable livelihood alternatives for drylands populations should become part of national strategies to com...Deep sleep short-circuits brain's grid of connectivity
...ransparent and may not always be in use. "What we needed to do was stimulate an area of the brain and see if it talks to another part. We have a tool to do that now," says Tononi, referencing one of only a handful of machines in the world capable of stimulating precise regions of the brain from outside the......ids which form the basis of proteins). Volunteers needed for phase 2 For phase 2 of the study, which is due to begin in September, ESA, the French space agency CNES and the MEDES Institute are looking for twelve new female volunteers from the European Union. " The international aspect of the selection pr...