Confocal imaging promises early detection of skin cancer
...anufacture costs ?by stripping away everything not needed for skin diagnosis, redesigning optical components and producing a user-friendly design. “We can cut these costs by a factor of ten, resulting in a 20,000-euro machine that is affordable for many outpatient centres.?/p> Trials at two university h...Cellular Defects in Premature Aging Disease are Reversible
...rder to achieve a potential therapeutic effect, we needed to completely eliminate the mutant protein," said Scaffidi. The NCI researchers designed a chemically stable DNA oligonucleotide ?a short DNA sequence that the cell wouldn't be able to degrade ?that would bind to the mutant splice site and prevent t...Man-made wetland's effectiveness similar to natural marsh
...itsch said. But about 10 to 25 times that many are needed in the Mississippi watershed region in order to see a significant reduction of nitrogen levels in the Gulf. ...Of mice and men's (and women's) contraceptives
...cise order of synthesis of many essential proteins needed to create functional gametes. We think the absence of the MSY2 protein causes problems in the timing of sperm or egg development. We're working hard on understanding this mechanism." A similar human equivalent of MSY2, Contrin, has been identified b...wFleaBase: the Daphnia genome database
...ciplinary research program to create the resources needed to study genes that affect ecological and evolutionary success in natural environments. Description These tools include the genome database wFleaBase, which currently contains functions to search and extract information from expressed sequenced tags,...Discovery clarifies role of peptide in biological clock
...in Arts & Sciences, has discovered that VIP is needed by the brain's biological clock to coordinate daily rhythms in behavior and physiology. Neurons in the biological clock, an area called the suprachiasmatic nucleus (SCN), keep 24-hour time and are normally synchronized as a well-oiled marching band c...Designing vaccines by computer
...formation to create a theoretical model of what is needed for one of these fragments to trigger an immune response. They can then employ computers to search for similar sequences in the thousands of sequences now available. When the search finds something promising it can be experimentally tested to see if ...Mouse with designer liver has enhanced glucose tolerance, insulin response
...und an elevated level of Akt/PkB kinase, an enzyme needed for insulin signaling, and elevated activity of IRS proteins. There was no activation of another enzyme, Erk, which is elevated in normal liver in reaction to insulin stimulation. Dr. Feng concluded that the function of Gab1 in normal liver cells is ...Microscopes at microscopic size
...reatment by reducing the number of hospital visits needed for tests. The initial research has led to the creation of a spin-out company, BioStatus Ltd, supported by a BBSRC Small Business Research Initiative grant. BioStatus has developed the research to refine the fluorescent probe technology and also to ...Radio-tracking associated with 'dramatic shift' in water vole sex ratio
...io-collars and sex ratio, although further work is needed to establish a causal link. According to Moorhouse and Macdonald: "We would expect any such effect to be species-specific, but our results will alert those studying other small mammals to look for similar associations. Our findings are a reminder tha...Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes
...igestive components of the pancreas, which are not needed to treat diabetes, develops after cross-species transplantation of such primordia. Even the endocrine part of the pancreas, where insulin is made, is different. "There are no structures similar to the islets of Langerhans, only individual endocrine...Pair of cancer genes found to drive both cell migration and division
...es already known to control cell movement are also needed for proper cell division. They report their findings in the April issue of Developmental Cell. The researchers discovered that the two genes are required for a dividing cell's halves to separate, raising the possibility that interfering with them co...Asymptomatic HIV babies could use earlier treatment
...ropriate for everyone.?/p> Clinical trials are needed to determine if every infected newborn should be treated or if some subsets of infants will benefit more than others, Maldonado explained. In the meantime, the findings emphasize the importance of testing pregnant women for HIV and watching for signs...Beneficial Beetles Battle Pesky Saltcedar
...etle. Besides disrupting the natural surroundings needed by native plants, birds, fish and other forms of life, saltcedar plays havoc with farm roads and fields. For example, when rivers and streams overflow their banks, saltcedar bushes can trap natural flood debris, blocking waterflow and causing new, er......ofitable option if the quantities of the substance needed are small or if the growth can be optimised in combination with other reared organisms. Nicole de Voogd's research was funded by NWO. ...$5.1 billion would save 6 million children
... of child death were available to all children who needed them. Universal coverage levels from 2000 for drugs and other materials, delivery of treatment, program management and support were calculated to obtain the average cost to save a child's life. The cost of some of the interventions, such as vaccines ...Research may provide new link between soft drinks and weight gain
...researchers say that further studies in humans are needed to determine if high-fructose corn syrup in soft drinks is directly responsible for the current increase in human obesity. ...New miniaturised chip dramatically reduces time taken for DNA analysis
... and thickness as a fingernail and reduce the time needed to identify DNA chains to several minutes or a few...oratories, but until now the experimental measures needed were not suitable for in situ analysis. By using the new sensors developed by UAB scientists, the ti...Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show It's Snot
...chronic sinus infection patients far exceeded that needed to damage the nasal and sinus membranes and make them more susceptible to infections such as chronic sinus infection. To conduct this investigation, Dr. Ponikau and fellow researchers collected specimens from 22 consecutive Mayo Clinic chronic sinus......ents a significant advance because the results are needed both for nature conservation planners and those en...e least explored by botanists. Greater efforts are needed in future to discover more about the plant life they contain. The project was conducted as a compone...