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Tag: "necessary" at biology news

Wisconsin scientists grow critical nerve cells

...k by an idea: Why not apply a chemical known to be necessary for a later stage of neuron development to a much earlier step in the process? The hunch paid off and turned out to be the final piece of the puzzle. The discovery, says Zhang, demonstrates that human stem cells do not necessarily differentiate in ...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...erferon effect. Further functionalanalyses will be necessary to map the molecular mechanisms in detail.Besides the Rheumatology Clinic at Uppsala Akademiska Hospital,hospitals in Umeå and Lund, in Sweden, and several hospitals in Finlandas well as one hospital in Reykjavik provided the project with DNAsamples ...

Novel technology detects human DNA mutations

...terest. Once that base pair is located, it is then necessary to determine if either of the bases is mutated (i.e., has SNPs). Nanosphere's technology can rapidly, easily, and accurately interrogate both bases in the pair to determine if they are homozygous (i.e., both are mutant or normal) or heterozygous (i.e...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...rograms that regulate stem-cell differentiation is necessary for harnessing this potential. ### This work was supported by grants from the National Institutes of Health. Epstein's coauthors are Deborah Lang, Min Min Lu, Li Huang, Kurt A. Engleka, Maozhen Zhang, Emily Y. Chu, and Sarah Millar from Penn; and S...

Timing is everything: First step in protein building revealed

...re and then releases a factorknown as eIF1, a step necessary to let it continue reading the assemblyinstructions. Even though yeast are the most primitive relatives ofhumans, the protein-building machinery, or ribosomes, of each are quitesimilar. "Theidea is to really know at the molecular level how life is p...

Plants, animals share molecular growth mechanisms

... protein strings, called actin filaments, that are necessary for cellular growth, said Dan Szymanski, agronomy associate professor and lead author of the study. Knowledge of the biochemical reactions involved in this process eventually may allow researchers to design plants better able to protect themselves fr...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

...onkeys and humans, Langstonstresses that it may be necessary for far more DA neurons to surviveand for that survival to be long lasting in order to render thisapproach as a useful therapy in humans.Langston highlights that "clearly the study reported here will advanceresearch aimed at validating the use of ste...

New Technique for Tracking Gene Regulators

...entation andbiological and computational resources necessary to sequence the entirehuman genome, identify all functional genes, and help transfer thisinformation and related technology to the private sector for thebenefit of society (see DOEgenomes.org).Related Links * John Dunn's web site * Brookhaven B...

Gene therapy converts dead bone graft to new, living tissue

... as a kind of "calcium bank." If calcium, which is necessary for such important functions as maintaining the brain and heart, runs low, cells called osteoclasts dig out the calcium from our bones. This is why doctors encourage post-menopausal women to take calcium supplements, so that the body doesn't raid the...

Gene variations explain drug dose required to control seizures

...enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to find the dose ...

U-M scientists find genes that control growth of common skin cancer

...archers found that sustained expression of Gli2 is necessary forthe continued growth of these tumors. When Dlugosz and colleaguesturned Gli2 off, the BCC tumor cells stopped growing and wereeliminated by a programmed cell death process. These results areconsistent with previous work from other labs studying di...

Highly adaptable genome in gut bacterium key to intestinal health

...seat at the table. The bacterium also produces the necessary utensils to break different types of carbohydrate chains into 'bite-sized' pieces; the utensils are a variety of enzymes directed at different types of carbohydrates." When a set of germ-free mice were fed a simple-sugar diet--instead of a complex-c...

Scientists discover unique microbe in California's largest lake

..." Wood explains. "Untilrecently, we thought it was necessary to use visible light to produceoxygen through photosynthesis, but now we know there are at least threeorganisms that can do this using infrared radiation as well."All three of these organisms are closely related species ofAcaryochloris, but the other...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

...aid. "The presence of growth hormone and IGF-1 is necessary for maintenance of cognitive function and prevention of cartilage degeneration," Sonntag and his colleagues reported in an article in Endocrinology, published on-line today. But the hormones also increase cancer and other diseases that limit lifespan...

Bird Brains Show How Trial and Error May Contribute to Learning

...rebrain that seems to generate the trial and error necessary to master sophisticated motor skills, such as singing in birds or speech and sports in humans. "It means this part of the brain is important for instructing or allowing changes in the song," said Mimi Kao, first author of a paper in the February 10,...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...iscovery. "Maybe the target protein has a good and necessary role in 10 interactions, but the 11th is the only one we would need to eliminate," said Ideker. "What we really want are drugs that interfere with just that one disease-causing interaction." Systems biologists such as Ideker say their ultimate goal ...

X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power

...o thinking it is flying freely through the air, is necessary to produce a stable pattern of wing motion and enabled the team to capture X-ray images at different stages of muscle contraction. By combining the technologies, the researchers could reconstruct a ‘movie?of the molecular changes in the powerful musc...

Applied Biosystems Introduces Advanced Gene Expression Service Provider Program

...nce scientific research while helping them achieve necessary return on investment, was announced today in advance of this weekend’s annual World Microarray Congress in Vancouver, Canada. The Applied Biosystems Expression Array System forms the technical platform for the program and can be optionally bundled w...

Harnessing microbes, one by one, to build a better nanoworld

...nce scientific research while helping them achieve necessary return on investment, was announced today in advance of this weekend’s annual World Microarray Congress in Vancouver, Canada. The Applied Biosystems Expression Array System forms the technical platform for the program and can be optionally bundled w...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...e. He also stressed the interdisciplinary approach necessary to face the challenges related to stem cell research. "Embryonic stem cells have the power to develop into every type of human tissue," said Witte, who also is a professor of microbiology, immunology and molecular genetics, and a Howard Hughes Medica...

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