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Chemists create 'Superbowl' molecule; May lead to better health

...mpounds such as [the anticancer drug] taxol in the near future," he says, but cautions that the superbowl molecule has not yet been tested in animals or humans. Until then, no one knows yet when this experimental molecule will actually enter the consumer market, but any useful application is likely to tak...

Man and mouse share genome structures

...pectedly, they also found tags idling over regions near genes. The researchers think these sites have important regulatory functions, because the methylation patterns are similar in comparable portions of the mouse genome. Until now, they'd been missed by more standard genome analysis tools. Most excitin...

Timing is everything: First step in protein building revealed

...icals. Whentwo fluorescently labeled molecules are near one another, thefluorescent chemicals subtly interact, which changes the color orwavelength of light that is given off. If the distance between thefluorescent molecules changes, the color of the emitted light changesas well.The researchers successful...

Researchers Uncover Key Step In Manufacture of Memory Protein

...poor long-term memory. Dr. Loh added that, in the near future, an understanding of the chemical mechanism she and her colleagues deciphered in the current study may provide insight into long-term memory deficits. She explained that other researchers have learned that some human beings lack normal CPE due...

The secret to longevity in tubeworms

...rements of sulfide and sulfate fluxes in the water near the vents do not match the observed tubeworm colony size and individual longevity, leading Cordes et al. to propose that L. luymesi also uses its roots to release sulfate back to the microbial consortia from which it draws its sulfide. Without this r...

Found: Missing sequence of the human Y chromosome

...e DNA sequence: a 554-kilobase-pair genomicsegment near the centromere of the human Y chromosome. This sequencecontains eight putatively active genes that could be implicated insex-associated height differences and gonadal tumor development. Thispericentromeric gap was one of the few holes remaining in t...

The secret lives of whales

...pical regions while males travel globally and feed near the poles. “For example, of the roughly one million sperm whales killed by whalers in the Antarctic Ocean, only one was a female,?says Payne. Ocean Alliance is testing its samples for 30 different pollutants. “Some of these are endocrine disruptors ...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

...ever there is another cell type in the environment near thebacterium, such as a human blood cell. They discovered how thesebacteria know when other cells are present, and respond accordingly.In the laboratory, the team found that Enterococcus releases twosubstances into the environment. One substance stic...

Researchers reveal the infectious impact of salmon farms on wild salmon

...ile salmon was 73 times higher than ambient levels near the farm and exceeded ambient levels for 30 kilome...ass and build resistance. The location of the farm near the natal rivers undermines this natural coping strategy. The field study also discovered a new cau...

New Clues Add 40,000 Years to Age of Human Species

...17 issue of the journal Nature. The fossils, from near the town of Kibish, are far more ancient than rese...sil human remains found at the Omo River to an age near 195,000 years ago, say the researchers, an age that agrees with estimates from genetic studies for t...

Same mutation aided evolution in many fish species, Stanford study finds

...ne local species the group collected from a stream near Fresno. Perhaps mutations in the two other genes cause problems for the fish in addition to reducing the number of armor plates, Kingsley said. Most of these fish evolved independently from marine ancestors that are covered head to hind fin in body ...

New studies suggest airborne SARS transmission is possible

...y, from Hong Kong, shows patients in hospital bays near a SARS patient had a much higher infection rate than patients in distant bays, consistent with the possibility of airborne SARS transmission, according to an article in Clinical Infectious Diseases. Both articles are published in the journals' May 1 ...

Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed

... Maximum. But evidence from an ice core extracted near Siple Dome from 1997-99, along with other calculat...ded a picture of temperature and snowfall patterns near Siple Dome. The layers get thinner and thinner with depth, as more ice and snow piles up. But the th...

First real-time view of developing neurons reveals surprises, say Stanford researchers

...respond to images moving in a certain direction or near the left or right side of the visual field. What they found was a surprise. As soon as the neurons were old enough to respond to the LCD screen, they specifically fired when they sensed only one type of movement. When the tiny square moved left to r...

UCSD discovery may help extend life of natural pesticide

...will now be possible to monitor insect populations near fields where Bt is used and catch insect resistance in its early stages by looking for changes in glycolipids," said Aroian. "If changes are detected, switching to another pesticide, perhaps even another variety of Bt that works through a different m...

Scientists identify new model Of NK cell development

...n throughout the lymph nodes, but rather localized near special sites called parafollicular regions, rich in T cells and NK bright cells. "We thought this was pretty interesting because we know that in order for these NK precursor cells to grow and differentiate, they need one of two cytokines, interleuk...

Scientists solve structure of key protein in innate immune response

...ure shows that CD14 has a large hydrophobic pocket near its amino terminus," says Dr. Lee. "We propose tha...fere with LPS signaling cluster in a separate area near the pocket suggesting that the areas around the pocket are important in LPS transfer. Not only do t...

Scientists find fossil proof of Egypt's ancient climate

...d life. Evidence for the hominin presence abounds near the lake in the form of Middle Stone Age artifacts such as stone scrapers and blades. "The artifacts provide a record that people were coming to the lake," said Smith. "Genetic evidence suggests that 100,000 to 400,000 years ago was a critical time ...

Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments

... up by the middle muscular layer of the heart wall near the injection site. Inside the cell, the DNA encoded VEGF-2 expresses itself which in turn stimulates the growth of new blood vessels by promoting the proliferation of endothelial cells in the heart. New blood vessels are required to provide oxygen-...

Protein offers way to stop microscopic parasites in their tracks

...s, which are able to clip off sections of proteins near the surface of the cell membrane. Using other rhomboid proteases as guides, Brossier identified genes for five rhomboid proteases in Toxoplasma. Scientists showed that the parasite used at least four of those genes to make active proteases. When the...

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