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Tag: "nanoparticles" at biology news

Researchers make nanosheets that mimic protein formation

How to direct and control the self-assembly of nanoparticles is a fundamental question in nanotechnology. Univ...e we know how to manipulate the forces between the nanoparticles and their ability to self-organize, it will help us in a variety of practical applications from ligh...

Electric jolt triggers release of biomolecules, nanoparticles

...f burst of electricity to release biomolecules and nanoparticles from a tiny gold launch pad. The technique could someday be used to dispense small amounts of medicine on command from a chip implanted in the body. The method also may be useful in chemical reactions that require the controlled release of extremely ...

U-M researchers use nanoparticles to target brain cancer

... designed to kill brain cancer. What's more, these nanoparticles can be used to image and track tumors as well as d...a drug called Photofrin along with iron oxide into nanoparticles that would target cancerous brain tumors. Photofrin is a type of photodynamic therapy, in which the ...

Nanoparticle assembly enters the fast lane

...rchers found a way to control the assembly of gold nanoparticles using rigid, double-stranded DNA. Their technique ...d in the laboratory is capped onto individual gold nanoparticles and customized to recognize and bind to complementary DNA located on other particles. This process f...

Sandia researchers discover way to see how a drug attaches to a cell

...sing light to grow a nanometer-sized particle. The nanoparticles can then be imaged with electron microscopy to reveal the location of the drug receptor molecules on the cell," Shelnutt says. "This type of nanotagging technique might be used in non-biological applications as well - such as finding flaws in semicon...

Scientists win grants to develop $1,000 genome sequencing technology

...s, with one fragment of DNA attached to individual nanoparticles in the arrays. The investigators will attempt to demonstrate that more than 1 billion individual DNA molecules can be sequenced simultaneously....

Scientists design simple dipstick test for cocaine, other drugs

...ng some of the gold nanoparticles. The red-colored nanoparticles then migrate along the membrane, where they are captured by the streptavidin and form a red line. The intensity of the line is an indicator of how much of the targeted molecule was in the sample solution. So far, the researchers have successfully d...

NHGRI aims to make DNA sequencing faster, more cost effective

...with sub-micrometer dimensions for ordering single nanoparticles and DNA molecules. The investigator will attempt to demonstrate that more than 1 billion individual DNA molecules can be sequenced in massive parallel though a process involving cyclic sequencing by ligation, a process where an enzyme is used to join...

Gold nanoparticles prove to be hot stuff

Gold nanoparticles are highly efficient and sensitive "handles" for biological molecules being manipulated and tracked by lasers, but they also can heat up fast--by tens of degrees in just a few nanoseconds--which could either damage the molecules or help study them, a...

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

... UC San Diego have discovered that iron-containing nanoparticles being tested for use in several biomedical applica...ent for mammals and most life forms and iron oxide nanoparticles were generally assumed to be safe," said Sungho Jin, a professor of materials science at UCSD and se...

Coated nanoparticles solve sticky drug-delivery problem

...Johns Hopkins researchers have found a way to coat nanoparticles with a chemical that helps them slip through this ...getting through. We've found a way to keep helpful nanoparticles from sticking to mucus, and we learned that the openings in the mucus 'mesh' are much larger than mo...

Nanoparticles for delivery of prostate cancer treatment

... produce than adenoviral vectors," said Garen. The nanoparticles will have a tag on their outside that binds to the tumor blood vessels. After binding, they are taken up by the cells and unload the gene that codes for the Icon, allowing the cells to produce and secrete the Icon. "The key is to have an efficient...

Nanoparticles can track cells deep within living organisms

... St. Louis, living cells gobbled up fluorine-laced nanoparticles without needing any coaxing. Then, because of the ...ickline, M.D., and Gregory Lanza, M.D., Ph.D., the nanoparticles could soon allow researchers and physicians to directly track cells used in medical treatments using...

Buckyballs used as 'passkey' into cancer cells

...discovered a new way to use Rice's famed buckyball nanoparticles as passkeys that allows drugs to enter cancer cells. The research appears in the Jan. 21 issue of the journal Organic and Biomolecular Chemistry. All living cells defend themselves by walling off the outside world. Cell walls, or membranes, form ...

Nanotechnology shows promise as next wrinkle fighter

...e University chemical engineer has discovered that nanoparticles can stop thin polymer films from buckling and wrin...odermabrasians to lasers to Botox injections ? and nanoparticles are poised to join the war by warding off dreaded buckles in human skin. Ilsoon Lee, an assistant ...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...rotect it from the body's defense mechanisms. The nanoparticles accumulate mainly in the lungs, particularly in the tumors, where the genes repeatedly express FUS1 tumor-suppressing proteins. Lung cancer is the leading cause of cancer death in the United States, causing 160,000 deaths annually. About 80 pe...

Scientists create dual-modality microbeads to improve identification of disease biomarkers

...taneously or sequentially add optical and magnetic nanoparticles into the beads. Adding magnetic nanoparticles allows the use of a magnetic field to attract and easily remove the beads from a liquid sample. "...

Dual gene therapy suppresses lung cancer in preclinical test

Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human n...rcher on the project. The genes wrapped in the nanoparticles were p53, a well-known tumor suppressor that works by causing defective cells to commit suicide and ...

Cancer tip -- Nanoparticles can damage DNA, increase cancer risk

...hers at the University of Massachusetts say. Such nanoparticles are currently in use in electronics, cosmetics, an...al by conventional filtering techniques. When nanoparticles find their way into cancer cells, they can wreak havoc, according to Sara Pacheco, an undergraduate ...

Rapid, Low-Cost DNA Testing

...rbs on negatively charged citrate ions on the gold nanoparticles while double-stranded DNA does not. Given that both single-stranded and double-stranded DNA are (nominally) negatively charged, this proven phenomenon intrigues the research group. The new assay determines whether a fluorescently-tagged short prob...

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