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Tag: "nanoparticle" at biology news

DNA Molecules Used To Assemble Nanoparticles

...r, more efficient way to produce a wide variety of nanoparticle drug delivery systems, using DNA molecules to bind... is notoriously difficult and time-consuming. The nanoparticle system used by Baker's lab is based on dendrimers, star-like synthetic polymers that can carry a vas...

Novel technology detects human DNA mutations

... of the versatility of our proprietary ClearReadTM nanoparticle technology," said William Moffitt, Nanosphere's President and CEO. "This study and the use of nanoparticles to dramatically increase sensitivity in our other proprietary applications -- such as bio-barcode for ultra sensitive detection of proteins --...

Tiny particles could solve billion-dollar problem

...rt base, pure palladium nanoparticles and a hybrid nanoparticle developed by Wong that consists of a gold nanoparticle covered with a thin coat of palladium atoms. As metal particles get progressively smaller, a higher...

Scientists develop new color-coded test for protein folding

...s color when a protein molecule attached to a gold nanoparticle folds or unfolds. The new technique, which works o...mplicated proteins," Zare said, noting that a gold nanoparticle sensor could turn out to be a quick and inexpensive way for doctors to identify antibodies and other...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...en add a second ingredient that consists of a gold nanoparticle core surrounded by hundreds of identical DNA strands, which serve as hundreds of "bio-bar-codes" the researchers can detect at the end of the test. Ultimately, the gold-DNA particles and magnetic particles sandwich the biomarker targets. A magnet se...

Nanoparticles offer new hope for detection and treatment

...., professor of medicine, are co-inventors of this nanoparticle technology. The effectiveness of the nanoparticles...hat make it especially interesting as a target for nanoparticle therapy. Melanoma has a horizontal phase, when it spreads across the skin surface, and a vertical ph...

Nanoparticle Breast Cancer Drug Approved by FDA

...ineered using a proprietary process (protein-bound nanoparticle technology) to create tiny particles (nanoparticles 100th the size of a red blood cell) in which the active chemotherapeutic drug, paclitaxel, is bound to a naturally occurring protein called albumin. By using this nanotechnology, the active compone...

MIT engineers an anti-cancer smart bomb

... cells unscathed. MIT researchers have designed a nanoparticle to do just that. The dual-chamber, double-acting,...eding the tumor then collapse, trapping the loaded nanoparticle in the tumor, where it slowly releases the chemotherapy. The team tested this model in mice. The do...

Using nanoparticles, in vivo gene therapy activates brain stem cells

... and cell types. A key advantage of the UB team's nanoparticle is its surface functionality, which allows it to b...orescent marker gene, demonstrating the ability of nanoparticle technology to deliver effectively genes to specific types of cells in the brain. Using a new optica...

Breakthrough: Scientists create world's tiniest organic particles

...thods for fabricating transistors with the organic nanoparticle world," said Bruce Boucher, president of Liquidia. "It is truly a revolutionary discovery." ...

'Smart' nanoprobes light up disease

... called "quenching" that involves tethering a gold nanoparticle to the quantum dot to inhibit luminescence. The tether, a peptide sequence measuring only a few nanometers, or billionths of a meter, holds the gold close enough to prevent the quantum dot from giving off its light. In their test system, the Rice te...

NJIT study shows nanoparticles could damage plant life

A nanoparticle commonly used in industry could have a damaging ef...atts, is the nature of the interaction between the nanoparticle and the root of the seed. "What is the mechanism of the interaction between the particle and the roo...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...by varying the size of the core and the shell. A nanoparticle combined with a hormone and cell-killing peptide i...d a molecular complex, combining LHRH with a 10 nm nanoparticle ?superparamagnetic ironoxide ?and a cell-killing peptide drug, Hecate. Leuschner and her co-worker...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

...eled model drug within them, in order to visualise nanoparticle uptake into target cells. The nanoparticles in question were designed for attachment to aptamers so that the binding properties of aptamers for targeting could be preserved. Additional design criteria consisted of the development of nanoparticles tha...

Researchers use 'trickery' to create immune response against melanoma

...eled model drug within them, in order to visualise nanoparticle uptake into target cells. The nanoparticles in question were designed for attachment to aptamers so that the binding properties of aptamers for targeting could be preserved. Additional design criteria consisted of the development of nanoparticles tha...

Cellular scale drug delivery from the inside out

... achieve external control, Lin is using iron-oxide nanoparticle caps which can be manipulated by a magnetic field. In a simple demonstration of the principle, Lin holds a refrigerator magnet up to a liquid-filled glass vial containing human cervical cancer cells grown in vitro that contain nanospheres capped with...

Gold nanoparticles could improve antisense cancer drugs

... strands of antisense DNA to the surface of a gold nanoparticle (forming an "antisense nanoparticle") the DNA beco...ore effectively than DNA that is not attached to a nanoparticle surface (as in commercial agents). When compared to antisense DNA complexed with commercial agents ...

Immune cell communication key to hunting viruses, Jefferson immunologists show

...lls. What they found surprised them. While the nanoparticle specifically bound to the surface of T-cells with receptors recognizing the viral-MHC complex, the control ?a biosensor that carried the same MHC protein with a different peptide not recognized by the T- cells ?unexpectedly also binded almost as st...

MIT nanoparticles may help detect, treat tumors

...o "self-assemble" or stick together. The resulting nanoparticle clumps are too big to get back out of the gaps. Further, the clumps have a stronger magnetic signal than do individual nanoparticles, allowing detection by MRI. "We inject nanoparticles that will self-assemble when they are exposed to proteases ins...

Researchers make nanosheets that mimic protein formation

...ty of practical applications from light-harvesting nanoparticle devices to new drugs which can act like proteins, ...ion from bright green to dark red depending on the nanoparticle size, are made from cadmium telluride crystals, a material used in solar cells. The sheets are about...

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(Date:9/19/2014)... a species which over thousands of years has adapted to ... substance that makes the cold dangerous for you. , This ... , and the cold provoking substance, called nonylphenol, comes from ... is suspected of being a endocrine disruptor, but when entering ... worm,s ability to protect the cells in its body from ...
(Date:9/19/2014)... plants regulate their symbiotic relationship with soil bacteria ... the plant structure from leaves into the roots ... the roots. This collaborative study was conducted by ... the Graduate University for Advanced Studies (SOKENDAI), and ... Japan. , Legumes, an important plant family ...
(Date:9/18/2014)... A new GSA Bulletin study uses ... Rio Puerco and Chaco Wash in northern New Mexico, ... salt cedar and willow, investigators were able to precisely ... They then combined this data with aerial imagery, LiDAR, ... of these arroyos. , Arroyos are deep, oversized channels ...
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(Date:9/19/2014)... NH 9/18/14) A leading Dartmouth researcher, working with The ... a paper published today in the Journal of ... increase the risk of melanoma. , "For the first ... length of these telomeres play a part in the ... study Mark Iles, PhD, School of Medicine at the ...
(Date:9/19/2014)... September 19, 2014 According to a ... the embattled blood-thinner Xarelto, named as defendants in several ... Pleas, have moved the court to dismiss those suits ... have sufficient connection with Philadelphia.* The cases include, for ... (No. 140304328; Pa. Comm. Pls., Philadelphia Cty.), which was ...
(Date:9/19/2014)... 19, 2014 (HealthDay News) -- U.S. military troops deployed ... skin cancer, according to a new study. ... researchers revealed. In some cases, military personnel developed blisters ... color, shape or size of their moles since being ... risk factors for skin cancer, the study authors noted. ...
(Date:9/19/2014)... Sept. 19, 2014 (HealthDay News) -- Pregnant women who live ... or low birth weight babies, a new study suggests. ... Canada, and found that expectant mothers who lived in a ... a 20 percent lower risk of very preterm birth (before ... preterm birth (30 to 36 weeks). Babies born to ...
(Date:9/19/2014)... Sept. 19, 2014 (HealthDay News) -- The U.S. Food and ... on Thursday. Trulicity is part of a class of once-a-week ... with type 2 diabetes. "Trulicity is a new ... existing treatment regimens to control blood sugar levels in the ... director of the FDA,s Office of Drug Evaluation II, said ...
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